2C-I or 'Smiles': The New Killer Drug Every Parent Should Know About

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shishigami

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http://shine.yahoo.com/healthy-living/2c-smiles-killer-drug-every-parent-know-234200299.html

Witnesses described the 17-year-old boy as "shaking, growling, foaming at the mouth." According to police reports, Elijah Stai was at a McDonald's with his friend when he began to feel ill. Soon after, he "started to smash his head against the ground" and began acting "possessed," according to a witness. Two hours later, he had stopped breathing.

The Grand Forks, North Dakota teenager's fatal overdose has been blamed on a drug called 2C-I. The night before Stai's overdose, another area teen, Christian Bjerk, 18, was found face down on a sidewalk. His death was also linked to the drug.

2C-I--known by its eerie street name "Smiles"--has become a serious problem in the Grand Forks area, according to local police. Overdoses of the drug have also be reported in Indiana and Minnesota. But if the internet is any indication, Smiles is on the rise all over the country.
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According data obtained by the American Association of Poison Control, half of those exposed to 2C-I in 2011 were teenagers. That statistic was before two fatalities and multiple overdoses were linked to the drug in North Dakota.

"The unfortunate thing is if kids who are overdosing on 2C-I go in to the hospital with a physical problem, a lot of times they can't test for it so it doesn't show up as a drug overdose," says Wold.

The fact that 2C-I is untraceable in tests makes it more of a challenge for doctors to treat. It also contributes to drug's growing popularity among high school and college-age kids.

"Synthetic drugs don't generally show up on drug tests and that's made it popular with young adults, as well as people entering the military, college athletes, or anyone who gets tested for drugs," Barbara Carreno, a spokesperson for the Drug Enforcement Agency, tells Shine.

2C-I may be undetected in drug tests, but it's effects are evident in emergency rooms.

According to James Mowry, the director of Indiana's Poison Control Center, 2-CI overdoses--on the rise in the state--and have been known to cause seizures, kidney failure, and fatally high blood pressure.
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While the drug's potential for overdose is apparent, the specific cases of fatalities are confounding. According to one site designed as a "fact sheet" for users, the dosage of the drug, which also comes as a liquid or a pill, is difficult to measure in powder form. When users snort the drug they could end up taking more than they realize, prompting an overdose. But in the case of Stai, the powder wasn't snorted, but melted into a chocolate bar and eaten.

Some speculate those "hobby chemists"--making the drug using powders shipped from China, acetone and plant-based materials--are to blame for concocting particularly strong or toxic batches.

"Anybody with a little money to front can import chemicals, mix, and sell it," says Carreno. "Many of these types of drugs were originally designed for research to be used on animals, not people." In fact, 2C-I was first synthesized by Alexander Shulgin, a psychopharmacologist and scientific researcher. He's responsible for identifying the chemical make-up of the so-called "2C" family, a group of hyper-potent psychedelic synthetics. In 2011, 2C-E, a twin sister drug to 2C-I, was blamed for the death of a Minnesota teenager and the overdose of 11 others.
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Sigh. I really like that part about Shulgin, failed to mention that he took them all as well.
 
Wow is this the first reported death from 2c-i? Alot of bullshit in the article though like its not hard to measure the powder with the proper scales.
God Damn it this piece of shit article is front page on Yahoo news. I just wrote the author a letter demanding a retraction but im not holding my breath. "smiles" 8(
 
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Seriously, where do they get these names for these drugs? I've never once in my life heard 2c-I referred to as "Smiles".

Is it pure ignorance? Are they just making this stuff up, or are people bullshitting them and skewing their sources?

It's really rather hilarious and angering at the same time.
 
Great to see they did their research. Christ. This kid overdosed on 25I. But hey, what difference does a benzylmethoxy group makes? Yawn.
 
why dont we just kill the people who write this shit? in my life theres far to many problems becose of these propaganda lies,will we just sit there and bitch about it doing nothing forever? when we say enough is enough and do something??
 
expected, its the news. the one comment that referenced pihkal got voted down. all you can do is push for a real drug education, or, really, any education is better than misinformation and lies
 
God a classic case of yellow jounalism. Acts like it's instant death and nothing else. No mention of the positive effects that are reason it's even used, nor that tylenol probably has killed more.
 
So this "hobby chemist" was making 2c-i in his apartment by combining powders shipped from China, acetone and plant materials. Shulgin must have updated the PIHKAL recipes in the latest edition. What a bunch of happy horseshit.

ISTR some talk that the kids who allegedly died earlier from 2c-e overdoses in Minnesota actually ODed on bromo-dragonfly (BDBF). That never set right with me. I can definitely see MDPV being sent accidentally as methylone or vice versa -- those are both chemicals which most of the big RC wholesalers are likely to have on hand. But I'd be very surprised if there's any big player in China or elsewhere who is keeping a large supply of BDBF on hand. (The original bromo deaths, IIRC, came about as a result of a mislabeled batch of 2c-b-fly which may have been a shitty synthesis. I'm not sure HOW someone could set out to synthesize 2c-e and end up with bromo-dragonfly instead.... ).

If the kids were actually taking an NBOMe, that would explain the overdoses: the NBOMes definitely can cause vasoconstriction in sufficient quantities. ISTR that the kids who died in Minnesota split a gram of "2c-e" between eight people or so and snorted it. 125mg of insufflated 2c-e would be one hell of a trip, and likely not a very pleasant one. 125mg of insufflated 25i-NBOMe could easily kill you or leave you with lasting damage. And while the NBOMes are famous for being orally inactive, I don't think I'd want to pour a gram of 25i-NBOMe into molten chocolate and then split the result with a friend. (Even 1% bioavailability would mean you just took the equivalent of 5mg of snorted 25I... yikes!)

Sadly, I expect to be seeing a lot more of these incidents. The NBOMes are extremely potent and very cheap on a dollars-per-dose basis: they also lack LSD's safety profile. And if someone gets a gram and decides to cut out some lines for his buds, or decides that if 2 tabs are good 20 will be even better, they are soon going to find that out.
 
Never heard of a death from 2c-i.
I have read of massive overdoses, 10x a regular dose, but nobody died from them.
But it is pretty hard to trust this reporter, so I still wonder if it really was 2c-i. If so, I wonder how much the kid took.
I can imagine someone snorting a fat half-gram line of 2c-i, due to lack of education, and that such an overdose might be responsible for a death.
 
definitely wasn't 2c-i, stupid journalist.

Adam Budge gave police an empty baggie labeled “25iNBOMe,”

Read more: http://www.drugs-forum.com/forum/showthread.php?t=188208#ixzz27ArDSOcN
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source: http://www.inforum.com/event/article/id/364865/

now 25i consumed orally in chocolate... i don't know, maybe some got in under the tongue and in the gums but how much did they really absorb? Maybe they just snorted the powder, as baking it in chocolate or whatever is pointless. The story just doesn't add up, if you are buying $100 worth of a psych, you don't end up consuming half of it for a trip, just not economically sound. Maybe the bag didn't even have 25i in it, who knows.

i've consumed very large doses of 2c-i and 25i, 2c-i seems benign but high dose 25i can get a bit frightening, certainly wouldn't push it.
 
slimvictor said:
Never heard of a death from 2c-i.
I have read of massive overdoses, 10x a regular dose, but nobody died from them.
But it is pretty hard to trust this reporter, so I still wonder if it really was 2c-i. If so, I wonder how much the kid took.
I can imagine someone snorting a fat half-gram line of 2c-i, due to lack of education, and that such an overdose might be responsible for a death.
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There's an Erowid report from somebody who IVed approximately 170mg of 2c-i thinking it was speed paste(!!!!). He survived the experience just fine, although I don't think plans to shoot 2c-i again.
 
Yeah I like how all these are "all parents should know about" articles. I dont know about you guys but I'll probably be the most informed parent lol "what did I tell you about using substituted cathinones!"

And hobby chemists making it out of china powders and acetone, someone slept in intro to chem :(
 
amanitadine said:
Great to see they did their research. Christ. This kid overdosed on 25I. But hey, what difference does a benzylmethoxy group makes? Yawn.
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I'm looking for where it says that it was 25I-NBOMe? Was there an autopsy result? The article says 2C-I.

fwiw 2C-I itself has been implicated in at least one really serious incident:

J Forensic Sci. 2009 Nov;54(6):1485-7.

Morbidity involving the hallucinogenic designer amines MDA and 2C-I.

Drees JC, Stone JA, Wu AH.

Department of Laboratory Medicine, University of California-San Francisco, San
Francisco, CA, USA.

A case is presented of a 39-year-old woman who suffered severe debilitation
because of a hemorrhagic stroke in the context of substance abuse. The patient
presented to the emergency room with rapidly diminishing mental status,
hypertension, and vasoconstriction; her friends provided a history of ingestion
of cocaine, 3,4-methylenedioxymethamphetamine (MDMA), and 2C-I, a novel designer
amine. A multi-targeted LC-MS/MS method for sympathomimetic amines and related
drugs in urine detected and quantified 2C-I and MDA, while ruling out MDMA. The
cause of the stroke was determined to be an underlying cerebrovascular
abnormality called Moyamoya, secondary to substance abuse. In clinical
laboratories, gas chromatography-mass spectrometry or liquid
chromatography-tandem mass spectrometry (LC-MS/MS) confirmation of a positive
amphetamine immunoassay is usually directed only towards amphetamine,
methamphetamine, MDMA and MDA. This report demonstrates the utility of testing
for a wider menu of compounds using LC-MS/MS in order to better characterize the
prevalence and toxicities of novel amines such as 2C-I.

PMID: 19878416 [PubMed - indexed for MEDLINE]
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^this was the kid who died back in June and there was all sorts of conflicting media reports at first regarding the circumstances. . The kids thought it was "mushroom powder", somebody stole it from somebody, yadada. . .but yeah, it was 25I, and somebody who should know better, toxicologist or coroner, reported such, and finished their sentence with " which contains the controlled substance 2C-I". Which is an interesting take on things!
 
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