2C-T-21 a retrospective summary
For the past 2 years or so I’ve taken 2C-T-21 at least 50 times. Probably a bit too much, but I thought I’d share some things I’ve noticed. I usually take 7-12 mg. Shulgin puts the dosage at 8-12 mg. Effects starts after 45-60 min, peaks around 2 h, starts do decline after 6 h and fully at baseline after 10-13 h.
The reason I’ve used it so much is because I find it easy to appear straight on it and that it is very benign in its side effects. Mydriasis is very slight. In the beginning – before I got some tolerance – I had some cathartic and therapeutic experiences which felt very good. Visually it only makes colors warmer if below 15 mg, maybe you can see some very slight movement in patterns and trees. It definitely enhances music, but not as much as LSD or MDMA. It is a tactile enhancer and great sexual enhancer – though it can make me too sensitive. I do get into a relatively mild psychedelic headspace, a bit like 10 mg 2C-T-2 or 15-17 mg 2C-B HBr. It is slightly energetic, but not in any forceful way. But it’s very nice to go for a walk or go biking during the first 4-5 hours. It has some empathogenic qualities and it makes social contact more rewarding.
The only negatives have been a bit of occasional mild diarrhea, occasional slight headache at the end (probably partly related to lack of hydration) and maybe some lasting ADD/short term memory effects – but that may also be related to my age (50+). Also, I don’t know how bad it is regarding 5-HT 2B agonism and potential to cause heart valve valvulopathy. As it is so benign, it is easy to take often.
Using it every week very slowly decreases the effect if dose is kept steady. With 2 weeks between doses I haven’t noticed any tolerance build up. I’ve tried to combine it with 2C-B but I didn’t find it synergetic. I got less effect of 2C-B than usual when I’ve taken 2C-B during the second part of 2C-T-21 trips, so there’s definitely some cross tolerance. It is possible to insufflate 2C-T-21, but dosage equipotent to oral administration is probably closer to 1/3 than 1/2. I’ve not taken dosages over 16-17 mg, but according to reports it starts to become more visual above 16-17 mg. But if I want visuals, I have many other substances better suited for that. 2C-T-21 combines well with a little alcohol, but seems to potentiate alcohol if larger amounts are drunk, which may result in the usual things too much alcohol can result in and really bad hangovers. Or it just makes you feel more sober until the effect declines and then the alcohol suddenly takes over and you find yourself more drunk than you thought you were.
In conclusion – a perfect substance to get some light and easy change of everyday consciousness, good for psychotherapeutic introspection and release of suppressed feelings and good for enhancing sex (first 6 hours or so). Too bad it is so rare. Probably an excellent substance for anxious people trying psychedelics for their first time.
