That would bee a fantastic breakthrough!, despite it being ancient knowledge, it's well known too just how slow on the uptake politicunts are.
But even in the context of actual, genuine inadvertent consumption of psilocybin mushrooms in an effective psychotropic dose surprising a would-be consumer of only wild fungi of food value as a delicacy, 'neurotoxin' is an awfully strong word to use, and IMO not in the least applicable. It might well panic someone, or make them vomit, possibly, if they really weren't expecting psilocybin mushrooms in with their plate of sulfur polypore, boletes, parasol, for some misadventurous ID related reason, or say, somebody found Weraroa, and without cutting them through, believed them to be tasty puffballs and fried them up.
But neurotoxin? no. Muscarine is a neurotoxin, although not to be concerned about in the levels found in Amanita muscaria, which actually contains only miniscule quantities. Lethal quantities are to be found in some Inocybe species though, although one of the more easily hospital-treatable mycotoxidromes, given it's responsive to atropine if required for bradycardia, etc.
Monomethylhydrazine-N-formylhydrazone (gyromitrin, a pro-drug form of toxic monomethylhydrazine, from false morels), that is a fucking neurotoxin, un-decarboxylated ibotenic acid, is, sure, or acromelic acid, bona fide card carrying nasty ass neurotoxin that causes LOOOONG lasting (years even) painful thermo-responsive allodynia via excitotoxic effects on ionotropic glutamate receptors, possibly kainate type, in the spinal cord, from Clitocybe acromelalga, and C.amnoelens. That sort of thing, is a fungal bloody neurotoxin, not psilocybin.
Even if it produces ill effects on someone, it isn't a poison, it's a bad response to the dynamic psychological effects of the substance, unpleasant to the subject. Or some GI squirrely guts due to the serotonin receptors present in the GI tract. But not a POISONING....
In terms of the good, the bad and the truly heinously virulent ugly motherfuckers of the mycological chemical world, psilocin/psilocybin is a veritable angel. You cannot compare a subjective panic response to a strange psychic effect, to actual, physical neurological damage, or things like cyclopeptide toxins which rip the liver to shreds, allenic norleucine that rapidly attacks the kidneys (Amanita smithiana fr.ex), the paraquat-esque bipyridyls from deadly Cortinarius webcaps that cause severe, very delayed kidney failure, or the rhabdomyolytic toxins from certain Russula (R.subnigricans) and Tricholoma flavovirens if eaten to excess in the latter case (formerly considered good eating, but T.flavovirens, syn. T.equestre, the man on horseback, or knight's shield, actually contains toxins that if multiple meals are eaten, and too much mushroom is consumed over a few days can result in severe rhabdomyolysis, and the Russula subnigricans, that is actually lethal, ripping apart muscle tissue from the inside, flooding the body with it's breakdown products that then shuts down the kidneys, in addition to directly attacking and damaging cardiac muscle tissue.
Psilocybin fungi aren't even in the running. No way, no how. Not unless you actually choke as you swallow them, is anyone going to die, save perhaps a little baby grazing and finding something like P.baeocystis, which I do recall, a long time ago, reading that a fatality occured. Still, one newborn infant, as a misadventure of the most tragic kind, does not a neurotoxin, or even a true poison make, IMO.
Some people are made sick even by things the rest of us eat. Honey fungi are an offender there, sulfur polypore sickens some who eat it, but I eat both, and I love sulfur polypore fritters in eggy bread batter, deep-fried. Yum.
