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Thread: Taking 1Mg Naltraxone and breaking down to 1Mcg doses

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    Taking 1Mg Naltraxone and breaking down to 1Mcg doses 
    #1
    I am not good with math. I am able to obtain some 1Mg doses of LDN Naltraxone and I want to dilute them in water to utilize for ULDN at a dose of 1MICROgram. How would I go about doing this?

    Thank you for the help in advance.
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    #2
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    Basic Drug Discussion

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    1 milligram = 1000 microgram
    1 liter = 1000 milliliter

    So assuming you wanted to dose 1mL of liquid at a time, you would dissolve in 1 liter of water. For the volume of your dose to be 0.25mL you would dissolve in 0,25L.
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    #3
    So, for 1 Microgram of Naltraxone, I would take 1 Liter of Water, add 1Mg tablet to the water and take out 1ml of liquid? Is that correct?
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    #4
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    Jekyl Anhydride's Avatar
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    If you follow CoolWhip's ratio: Yes, 1ml would = 1Microgram, If you used a 1milligram pill. Even if it's a 30 or 50 mg pill the math is very similar, calculators help.

    I don't remember if the thread I replied to was yours, but here's some more info about ULDN:


    Ultra-low concentrations of naloxone selectively antagonize excitatory effects of morphine on sensory neurons, thereby increasing its antinociceptive potency and attenuating tolerance/dependence during chronic cotreatment.
    https://www.ncbi.nlm.nih.gov/pubmed/7479836
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