Study Red Maca May Reverse Prostatic Hypertrophy From AAS Use

CFC

CFC

Bluelight Crew
Joined
Mar 9, 2013
Messages
18,171
This isn't a recent study, but something I've been meaning to post for a while. I'd love a human study targeted at AAS-using athletes, but it's rodent stuff at the moment I'm afraid (and probably forever...).

Still, it might be of interest for anyone using AAS worried about prostate hypertrophy. Other more established 'natural' options include Saw Palmetto, but what's particularly interesting here is that the anti-hyperplasia effect, if treatment is commenced from day 1, appears to be stronger than with finasteride.




Effect of red maca (Lepidium meyenii) on prostate zinc levels in rats with testosterone-induced prostatic hyperplasia. (2012)​
​
​

Lepidium meyenii (maca) is a plant that grows exclusively above 4000 m in the Peruvian central Andes. Red maca (RM) extract significantly reduced prostate size in rats with benign prostatic hyperplasia (BPH) induced by testosterone enanthate (TE). Zinc is an important regulator of prostate function. This study aimed to determine the effect of RM on prostate zinc levels in rats with BPH induced by TE. Also, the study attempted to determine the best marker for the effect of RM on sex accessory glands. Rats treated with RM extract from day 1 to day 14 reversed the effect of TE administration on prostate weight and zinc levels. However, RM administered from day 7 to day 14 did not reduce the effect of TE on all studied variables. Finasteride (FN) reduced prostate, seminal vesicle and preputial gland weights in rats treated with TE. Although RM and FN reduced prostate zinc levels, the greatest effect was observed in TE-treated rats with RM from day 1 to day 14. In addition, prostate weight and zinc levels showed the higher diagnosis values than preputial and seminal vesicle weights. In conclusion, RM administered from day 1 to day 14 reduced prostate size and zinc levels in rats where prostatic hyperplasia was induced with TE. Also, this experimental model could be used as accurately assay to determine the effect of maca obtained under different conditions and/or the effect of different products based on maca.


https://www.ncbi.nlm.nih.gov/pubmed/21762188
 
All it's doing really is blocking the anabolic effect of test on the prostate, which is why it would be important to use it from the outset. It was less effective once growth had already started. So there's no indication it would dramatically attenuate any long-term harm caused - at least not from this study.
 
So, CFC my order from iherb has finally arrived, (in powder form) how much do you suggest for BPH..? The rat dose/kg seemed quite high in the above paper...

Saw palmetto on its own doesn't seem to help my condition..
 
CFC said:
This isn't a recent study, but something I've been meaning to post for a while. I'd love a human study targeted at AAS-using athletes, but it's rodent stuff at the moment I'm afraid (and probably forever...).

Still, it might be of interest for anyone using AAS worried about prostate hypertrophy. Other more established 'natural' options include Saw Palmetto, but what's particularly interesting here is that the anti-hyperplasia effect, if treatment is commenced from day 1, appears to be stronger than with finasteride.




Effect of red maca (Lepidium meyenii) on prostate zinc levels in rats with testosterone-induced prostatic hyperplasia. (2012)​
​
​

Lepidium meyenii (maca) is a plant that grows exclusively above 4000 m in the Peruvian central Andes. Red maca (RM) extract significantly reduced prostate size in rats with benign prostatic hyperplasia (BPH) induced by testosterone enanthate (TE). Zinc is an important regulator of prostate function. This study aimed to determine the effect of RM on prostate zinc levels in rats with BPH induced by TE. Also, the study attempted to determine the best marker for the effect of RM on sex accessory glands. Rats treated with RM extract from day 1 to day 14 reversed the effect of TE administration on prostate weight and zinc levels. However, RM administered from day 7 to day 14 did not reduce the effect of TE on all studied variables. Finasteride (FN) reduced prostate, seminal vesicle and preputial gland weights in rats treated with TE. Although RM and FN reduced prostate zinc levels, the greatest effect was observed in TE-treated rats with RM from day 1 to day 14. In addition, prostate weight and zinc levels showed the higher diagnosis values than preputial and seminal vesicle weights. In conclusion, RM administered from day 1 to day 14 reduced prostate size and zinc levels in rats where prostatic hyperplasia was induced with TE. Also, this experimental model could be used as accurately assay to determine the effect of maca obtained under different conditions and/or the effect of different products based on maca.


https://www.ncbi.nlm.nih.gov/pubmed/21762188
Click to expand...

Bump..
 
You must log in or register to reply here.
Top