alwayswrming
Greenlighter
- Joined
- Jun 18, 2016
- Messages
- 8
Hello all,
Referring to an archived thread, I saw a few users mention that inducing Cyp3A4 (Cytochrome P450 3A4) and inhibiting P-gp (P-glycoprotein) can result in a more pronounced effect for patients on some form of bup/naloxone combination therapy (I currently take Zubsolv, but took Suboxone for many years before switching). I am curious if there are any members here who have confirmed this more recently than the 2010 thread I am referencing. If so, I am also curious what solutions are easily available over the counter, if any. My doc also prescribed Gabapentin/neurontin, which I have, at times, noticed a positive interaction, but not consistently.
Thanks for the feedback
Referring to an archived thread, I saw a few users mention that inducing Cyp3A4 (Cytochrome P450 3A4) and inhibiting P-gp (P-glycoprotein) can result in a more pronounced effect for patients on some form of bup/naloxone combination therapy (I currently take Zubsolv, but took Suboxone for many years before switching). I am curious if there are any members here who have confirmed this more recently than the 2010 thread I am referencing. If so, I am also curious what solutions are easily available over the counter, if any. My doc also prescribed Gabapentin/neurontin, which I have, at times, noticed a positive interaction, but not consistently.
Thanks for the feedback