JohnBoy2000
Bluelighter
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- May 11, 2016
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Yes, which is why they generally don't tend to bother studying this kind of interaction. There's a lot of albumin.
That quote was made in relation to sertraline potentially displacing other highly albumin bound drugs
http://sci-hub.tw/https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0773.1996.tb00206.x
This paper however claims that - sertraline is mostly bound to alpha-1-acid glycoprotein, as oppose to warfarins albumin - which may explain why there is no interaction there, where it would be anticipated?
That also seems to the case for fluoxetine and paroxetine.
http://www.natap.org/2006/Glasgow/Glasgow_45.htm
This paper echoes that.