Short answer, it would help.
Fill-in answer: a Tramadol jackpot is like a ____________ made of irony.
Long answer, no one knows any more the actual etiology of SS, so who can say? The half-life of sertraline/Zoloft is like 22 hours, so you'd need at least five days to clear your system. Prozac/fluoxetine might be even longer, and I think is one of the case studies, where an adverse event happened like a month later. Meanwhile brain zaps, and throwing off your entire therapy with risk of dead-meds.
Why would you want to? Because it's better than hydrocodone, for you? And really, it sounds like most people put Tramadol as about as exciting as a Vicodin, anyway, but with a maximum daily dose you have to actually pay attention to.
(Some might argue that the risk of seizure is actually lower than the risk of addiction-triggering from a Vicodin script. I will leave the relative harm from either of those events happening as an exercise for our Bluelight work-study interns.
((I also still don't know the relative seizure risk for Tramadol, and am suspicious its for special-people anyway. I think bupropion is as high as 4% for the ~500mg/day dosing. I don't know if that's one in every 20 users, or 20 scripts, or if each time with that dose your risk is 1 in 20. But it fits with being in the Hexen family.
(((Ms. Love, if I may, and this is not to find fault with this thread per se, other than the info you seek is contained in your other threads already. In checking what your deal with Tramadol was, I noticed that of 19 threads started, 8 are presently closed; 1 was closed but reopened, and 1 should have been closed.
I know you have more closed threads than I've ever started, and more closed threads than I think I've closed as a "mod." The California Dept. of Motor Vehicles sends a cheerful note when you get two points on your license in two years, asking you to take a moment and reflect on your habits. Then again, maybe not the best advice, since I did reflect, right into a four-year hard suspension.