N&PD Moderators: Skorpio | thegreenhand
Amphetamines interact and bind to the TAAR receptor.
But what would happen if you had a drug that binded only dopamine to the TAAR receptor?.
Amphetamines interact and bind to the TAAR receptor.
But what would happen if you had a drug that binded only dopamine to the TAAR receptor?.
Dopamine (and serotonin too) bind at TAAR1 and activate it, but weakly compared to other compounds. (ref)
https://www.researchgate.net/public...ated_Receptor_1_Modulation_of_Dopamine_SystemSeveral studies have demonstrated that TAAR1 knockout mice display a supersensitive dopaminergic system, while activation of TAAR1 can reduce dopaminergic hyperactivity
What do you guys think about the text below?. I thought that Stimulants activate TAAR1, if so why does the study below say this?
https://www.researchgate.net/public...ated_Receptor_1_Modulation_of_Dopamine_System