N0 W4RN1NG
Bluelighter
- Joined
- Jul 16, 2008
- Messages
- 506
Hi guys, long time no post. Today I thought of something I really couldn't find an answer to.
I used to get WICKED "comedowns" from DA releasers and reputake inhibitors alike.
I have been on escitalopram 10mg for around a decade, along with a benzo and mood stabilizer (both usually switched after a year). Since I am incapable of "rolling", I quite enjoy stimulant binges. Usually plain old d-amphetamine, although methamp, adderall, fluorophenmetrazine, and even the odd propylhexedrine (shame me elsewhere, I already know I'm an irredeemable, shameless hedonist) make their appearance now and again.
Tried what is (putatively) a DARI or SNDRI the other day, 4F-PHP. Felt ok. Nothing like MDPV or aPVP, but similar to 4F-PVP, which I was one of the few who enjoyed.
I am quite, QUITE familiar with pyrovalerones, I have honestly done almost a quarter K of the original MDPV all to myself (over years), but that 4F-PHP brought me back - to what a comedown really is. It seems in my (ab)use of DA releasers, I have had absolutely NO comedowns over the past ~decade. I very rarely use NDRIs, so things like (m)ethylphenidate never interested me after I had a first taste, and I went through a phase with cocaine in my younger days, but for a long time now I have only been using DA releasers (barring my 2 years of insane MDPV use, which was so crazy that my "comedowns" were frequently cut short with a little "hair of the dog", if you catch my drift) and notices no comedown from them. So, call me stupid, but I am just putting this together now.
So, is there any known link to (prolonged) SSRI use muting the after effects of extreme DA-efflux? Perhaps it is not SSRI related, but an effect of ion channel mediation? (My mood stabilizers are always lamotrigine and/or oxcarbazepine - in yearly rotation) I am not complaining by any means, but when I see some of my friends in agony after a day or two "hard at work" I'd like to know if maybe there's a preventative measure that could be employed.
GOD IN HEAVEN I GET SO WORDY
TLDR: I get no comedowns, at all, from even the most heroic doses of DA releasers. I used to in the distant past, but not since being on an SSRI and mood stabilizer. NDRIs still give me comedowns.
Surely there is a mechanism to be explored here?
I used to get WICKED "comedowns" from DA releasers and reputake inhibitors alike.
I have been on escitalopram 10mg for around a decade, along with a benzo and mood stabilizer (both usually switched after a year). Since I am incapable of "rolling", I quite enjoy stimulant binges. Usually plain old d-amphetamine, although methamp, adderall, fluorophenmetrazine, and even the odd propylhexedrine (shame me elsewhere, I already know I'm an irredeemable, shameless hedonist) make their appearance now and again.
Tried what is (putatively) a DARI or SNDRI the other day, 4F-PHP. Felt ok. Nothing like MDPV or aPVP, but similar to 4F-PVP, which I was one of the few who enjoyed.
I am quite, QUITE familiar with pyrovalerones, I have honestly done almost a quarter K of the original MDPV all to myself (over years), but that 4F-PHP brought me back - to what a comedown really is. It seems in my (ab)use of DA releasers, I have had absolutely NO comedowns over the past ~decade. I very rarely use NDRIs, so things like (m)ethylphenidate never interested me after I had a first taste, and I went through a phase with cocaine in my younger days, but for a long time now I have only been using DA releasers (barring my 2 years of insane MDPV use, which was so crazy that my "comedowns" were frequently cut short with a little "hair of the dog", if you catch my drift) and notices no comedown from them. So, call me stupid, but I am just putting this together now.
So, is there any known link to (prolonged) SSRI use muting the after effects of extreme DA-efflux? Perhaps it is not SSRI related, but an effect of ion channel mediation? (My mood stabilizers are always lamotrigine and/or oxcarbazepine - in yearly rotation) I am not complaining by any means, but when I see some of my friends in agony after a day or two "hard at work" I'd like to know if maybe there's a preventative measure that could be employed.
GOD IN HEAVEN I GET SO WORDY
TLDR: I get no comedowns, at all, from even the most heroic doses of DA releasers. I used to in the distant past, but not since being on an SSRI and mood stabilizer. NDRIs still give me comedowns.
Surely there is a mechanism to be explored here?