What causes the major shitty after effect permanent .

[lemonman]

Hi,

I saw many reports of this.

They take the drug for a long time and then they have a bad trip, feel like they are dying, etc.. then they have a permanent feeling.
if they take the drug again, it just fucks them up...

what is the neuroscience behind this?.

thanks.

 

[JahSEEuS]

What drugs are we talking about?

 

[lemonman]

Dxm

 

[JahSEEuS]

I don't know much about what you speak of, but a quick google search turned this thread up.

http://www.longecity.org/forum/topic/61950-repairing-dxm-induced-damagereversing-dissociation/

I have experimented quite heavily many years ago. I found that the last time I took about 500 mgs I felt nothing and should stop.

When I was doing it on a weekly basis I would notice that I had difficulty focusing, remembering words, and mixing up words within my sentences. It was a very strange time in my life. That was about 10 years ago. The negative effects quickly dissipated when I stopped using it.

For me, Ketamine is still a pleasurable experience and every now and then I get the urge to see if DXM would work again. I had read stories that once it stops working, it stops for good.

 

[sekio]

I've always blamed this sort of effect on simple learned association. People naturally want to avoid the sort of experiences that produce anxiety/panic so once it happens once or twice on a drug it can be hard to not remember that sense of panic when you redose later.

Seems to happen more with psychedelics than anything else.

 

[sekio]

I've always blamed this sort of effect on simple learned association. People naturally want to avoid the sort of experiences that produce anxiety/panic so once it happens once or twice on a drug it can be hard to not remember that sense of panic when you redose later.

Seems to happen more with psychedelics than anything else.