2c-b-fly plugging no effect

[orangelicker]

Hey, it has been awhile since I’ve been on these forums but here is my question (since I couldn’t find the info I need with any searching):

What would be the best way to consume about 20mg of 2c-b-fly? I obtained 3x10mg “tablets” just a little bigger than a “microdot” would be, and I figured rectal administration would give be the best absorption & effects. Imagined one 10mg crushed up & dissolved in a couple mL water would be similar to 20mg oral.

However, no effects were noticed. I can’t figure out why. I believe the vendor is reputable & that the tablets I got are what they should be, but it seems odd to me.

Is there something I’m missing? Should be active plugged, yes? Are these better taken orally? I have 2x10mg left, and I was planning on just taking the entire 20mg orally if that should be effective. Thanks

Also, I guess I did not consider that I am prescribed Cimbalta (duloxetine) for its SSRI antidepressant effects. This is probably why I had no effects. Does anyone have info for that? How long would I want to wait after not taking any ssri before taking the fly?

 

[Ballz_Trippington]

The SSRI you ate on most likely filled or nullified the effects of the 2C-B-FLY.
Also, did you test your pills with a reagent test kit to verify it is 2C-B-FLY???

Most psychedelics should work rectally.

 

[Volsam]

In my experience, 2C-B-Fly is very unpredictable when it comes to consistent dosing and especially in conjuncture with other drugs. It's pretty benign by itself and as for plugging ROA - I felt it less than when eaten, although the come-up was way shorter. It manifested itself fiercely in combination with a couple of 4-substituted tryptamines and some amino acids - it was out of control to say the least. By itself, without anything else, its pretty benign, up to 20mg oral but even cannabis may bring out the "beast" it seems.

I recommend taking it orally, personally the best trip on this substance was a combo of 15mg of 2C-B-Fly and 15mg of 4-AcO-MET, preloaded with Agmatine, Phenibut and Magnesium.

I also do not recommend to take a lot of 2C-B-Fly as it has a strong binding affinity to 5-HT-2B receptor (Ki values are 0.9nM for 2C-B-Fly compared to 30nm for LSD, 4.1nM for Fenfluramine, 3.9nm for DOB, 3.6nM for 6-APB) that might result in some negative cardiovascular event.
Ki values are from https://pdsp.unc.edu/databases/pdsp...=&KiLess=&kiAllRadio=all&doQuery=Submit+Query

Also, I guess I did not consider that I am prescribed Cimbalta (duloxetine) for its SSRI antidepressant effects. This is probably why I had no effects. Does anyone have info for that? How long would I want to wait after not taking any ssri before taking the fly?

At least a week, the longer the better. Stopping SSRIs might not be a good idea since it was prescribed to begin with - but it's your call.

 

[DMTShroom1986]

In my experience, 2C-B-Fly is very unpredictable when it comes to consistent dosing and especially in conjuncture with other drugs. It's pretty benign by itself and as for plugging ROA - I felt it less than when eaten, although the come-up was way shorter. It manifested itself fiercely in combination with a couple of 4-substituted tryptamines and some amino acids - it was out of control to say the least. By itself, without anything else, its pretty benign, up to 20mg oral but even cannabis may bring out the "beast" it seems.

I recommend taking it orally, personally the best trip on this substance was a combo of 15mg of 2C-B-Fly and 15mg of 4-AcO-MET, preloaded with Agmatine, Phenibut and Magnesium.

I also do not recommend to take a lot of 2C-B-Fly as it has a strong binding affinity to 5-HT-2B receptor (Ki values are 0.9nM for 2C-B-Fly compared to 30nm for LSD, 4.1nM for Fenfluramine, 3.9nm for DOB, 3.6nM for 6-APB) that might result in some negative cardiovascular event.
Ki values are from https://pdsp.unc.edu/databases/pdsp...=&KiLess=&kiAllRadio=all&doQuery=Submit+Query

At least a week, the longer the better. Stopping SSRIs might not be a good idea since it was prescribed to begin with - but it's your call.

Great info Volsam, I enjoy small doses of 2C-B-Fly but have decided never to combine with Alcohol again after having the most horrific experience the other weekend. I had a few beers and decided to drop 20mg, which was reckless of me anyway but having taken this about 11 times since it came back on the scene I thought why not. I had another 4 beers so my total was 8 pints. What happened about 4 hours in was one of the most painful headaches of my life followed by extreme vomiting for about 4 hours.

the headache was worse than any migraine and lasted from midnight to 6am. The thought of doing my self in felt like an option and I am a really happy guy who would never think that. I won’t be mixing alcohol again and I am disappointed in my self for drinking again after quitting for such a longtime, I have been dry since.

I know what I had was 2C-B-FLY as it has been tested and tried, I would like to think that my experience was the alcohol but from what you wrote above it may have been the 2C-B-FLY as well. I have also been taking skate liver oil to clean my pineal gland and have experienced a lot of headaches recently.

anyway just wanted to put this out there as I have also seen a similar reaction regarding the vomiting from a friend when ingesting with a small amount of alcohol. I know my actions were reckless and should know better.

I have seen posts from others on the forum who have used this with alcohol I am sure, but it seems my body doesn’t like it.

 

[Xorkoth]

Did you clear your bowels before you plugged? If you have feces in there they'll absorb the majority of the dose.

 

[orangelicker]

Haha thanks for the replies guys. Yep I pood beforehand I’ve been plugging stuff for years and years so I have experience

but anyway I have the 2 x 10mg lil pills left so i will probably take them both orally in a few weeks. Doctor is tapering me down now. I just don’t like the things I have read and don’t think it really does anything.