TheAppleCore
Bluelighter
- Joined
- Jul 14, 2007
- Messages
- 5,511
Previous psychedelic drugs taken include 2C-E, 2C-C, 25I & 25C-NBOMe, LSD & prodrugs, DMT, DPT, DiPT, 4-AcO-DMT, 4-HO-MET, 4-AcO-DET, 4-HO-MiPT, 4-HO-EPT, and 4-AcO-DPT. My most recent trip was four weeks prior.
~~~
For my first trial with 4-HO-MPT, I attempted to replicate the conditions of my previous trip on 4-AcO-DET as closely as possible, for two reasons. Firstly, that trip was a beautiful success. But I also wanted to make a controlled comparison between the two molecules, as 4-HO-MPT and 4-HO-DET are closely related, being roughly equipotent positional isomers. Well, let me start by saying that I was shocked by just how much can change with a simple rearrangement of the nitrogen tail.
In the spirit of science, I measured out 26 mg 4-HO-MPT fumarate, the molar equivalent of 30 mg 4-AcO-DET fumarate, the dosage of my last trip. The physical characteristics of my sample were somewhat unusual: it was dense, clumpy, and difficult to get into solution. Eventually I got it to dissolve in a glass of orange juice, dosed at about 9:00 P.M., and headed outside for a nighttime stroll through my neighborhood. The first definite effect occurred at only T+0:10. I'm going to borrow a sentence from Hamhurricane's report on base MPT from 2011 here:
As the drug kicked in, the scenery of my environment, without morphing in any obvious way, nonetheless became a sort of cartoony caricature of itself. Additionally, everything was rendered in richly saturated technicolor. Believe it or not, 4-HO-MPT's visual effects resembled methoxetamine more than any psychedelic I've taken. This outrageous Looney Tunes visual style was in stark contrast to 4-AcO-DET, which created more of a dignified, 19th century impressionism with a sepia color palette.
Like with many psychedelics, my social inhibitions were lowered. I walked past a group of kids hanging out and smoking weed by the side of the road, and instead of ignoring them like I usually would, I made eye contact, waved and said hello, and we had a little friendly exchange. It was heartwarming to have some small kinship with these complete strangers, with whom I probably had very little in common. I had a fleeting vision in which I saw humanity as one continuous ocean, and death as waves lapping over the shore.
T+0:40 -- I get back home, and play the piano for about twenty minutes, jamming in a spontaneous stream-of-consciousness flow. I played with spacey, trippy, almost tongue-in-cheek chords: a fitting soundtrack to the living animation that I had entered.
T+1:00 -- I'm now peaking, and I head into my bedroom. When I check the time, I'm startled that only an hour has passed. By this point, the full character of the drug is apparent. My mood was simply cheerful and lucid; for contrast, I find that 4-AcO-DMT presents some combination of awe, terror, and rapture; 4-AcO-DET creates a dreamlike, distant apathy. Beside the cartoon effect, open-eye visuals were minimal, consisting of only some minor pareidolia, and I didn't notice anything in the way of closed-eye visuals or auditory hallucinations.
However, by far the most bizarre and memorable aspect of the entire trip was the bodily sensation -- or lack thereof, I should say. From head to toe, simply put, I was numb. When I closed my lips, or touched my tongue against my palate, I felt like I'd just gotten a shot of novocaine at the dentist. If I crossed my legs, I couldn't feel them pressed up against one another. My whole body felt like it was made of clay, which was especially true if I tried to get up and walk around, as movement was somewhat stiff and effortful. While I enjoyed the music I was listening to (Savant - Vario), my hearing was slightly muffled, as if there were cotton balls stuffed in my ears -- I recall something similar happening on 1P-LSD.
T+1:05 -- I take my blood pressure, which reads 138/78 (typically I'm around 110/70). Significantly elevated, but nothing terribly alarming. My pulse had risen from its usual ~80 to 88.
I continue to enjoy the music, while deeply contemplating the nature of the drug, and my relationship with psychedelics in general.
T+1:50 -- I notice that the effect is now slightly diminished. It very smoothly and gradually wanes over the next few hours.
T+6:00 -- As I'm lying in bed to fall asleep, I'm pleasantly surprised by some nice closed-eye visuals: colorful, three-dimensional, abstract geometry. Apparently the hypnagogic state helped to kick in the visual aspect of 4-HO-MPT for me, despite having come down for the most part.
T+~12:00 -- I wake up having slept reasonably well, however I have a sore neck, apparently from sleeping in a poor posture. My body still feels partially numb in the morning. It could be a coincidence, but I can't help but wonder if the analgesic aspect of the drug blunted the physical sensations that would have otherwise signaled me to properly adjust my bodily position during the night. No other negative after-effects persist into the following day.
Summary
In retrospect, after now trying every combination of methyl, ethyl, and propyl 4-substituted tryptamines, I'm led to conclude that extending the alkyl chains on the nitrogen tail seems to have a largely subtractive effect, with the dimethyl substitution having more or less the full spectrum of activity, and bulkier molecules being more selective in various ways. However, I should stress that this is not to say that psilocin is the superior drug, because sometimes these subtractions are very useful. For example, the subdued emotional tone of 4-AcO-DET offers a fascinating opportunity to experience its powerful mind-bending and sensory effects in a rather calm and objective way. The methyl-propyl substitution is a stencil which occludes quite a bit, but what does manage to shine through is very cerebral, as illustrated by the visual aspects, which were't strictly visible, but simply known for no apparent reason. However, 4-HO-MPT does introduce something completely unexpected for me, which is an anaesthetic numbing and motor paralysis.
I think 4-HO-MPT's cerebral focus and cheerful, colorful mood could make for a potentially fantastic trip at higher dosages, but at 26 mg, I found it a bit lacking. I suspect that I'd probably need at least 50 mg, if not more, to really push the psychedelia to a point of satisfying fullness. I'd love to explore the substance at higher dosages, but I have a couple concerns about that. First, the bodily anaesthesia was already quite strong, and frankly I found it unpleasant as it was, let alone at double the dose. Second, I'm uncertain how the hypertension will scale with increasing dosage. If this compound had a more thorough history of human use with a reassuring safety record, I would be much more adventuresome about it, but I'm not one to play guinea pig, so I take these physical factors seriously. I think, if I continue to experiment, I will push forward in small increments, perhaps 5 milligrams at a time.
Until then, I eagerly await any forthcoming reports on the drug from other psychonauts. Stay safe and have fun!
substancecode_4hommt
substancecode_tryptamines
explevel_firsttime
roacode_oral
exptype_positive
~~~
For my first trial with 4-HO-MPT, I attempted to replicate the conditions of my previous trip on 4-AcO-DET as closely as possible, for two reasons. Firstly, that trip was a beautiful success. But I also wanted to make a controlled comparison between the two molecules, as 4-HO-MPT and 4-HO-DET are closely related, being roughly equipotent positional isomers. Well, let me start by saying that I was shocked by just how much can change with a simple rearrangement of the nitrogen tail.
In the spirit of science, I measured out 26 mg 4-HO-MPT fumarate, the molar equivalent of 30 mg 4-AcO-DET fumarate, the dosage of my last trip. The physical characteristics of my sample were somewhat unusual: it was dense, clumpy, and difficult to get into solution. Eventually I got it to dissolve in a glass of orange juice, dosed at about 9:00 P.M., and headed outside for a nighttime stroll through my neighborhood. The first definite effect occurred at only T+0:10. I'm going to borrow a sentence from Hamhurricane's report on base MPT from 2011 here:
As the drug kicked in, the scenery of my environment, without morphing in any obvious way, nonetheless became a sort of cartoony caricature of itself. Additionally, everything was rendered in richly saturated technicolor. Believe it or not, 4-HO-MPT's visual effects resembled methoxetamine more than any psychedelic I've taken. This outrageous Looney Tunes visual style was in stark contrast to 4-AcO-DET, which created more of a dignified, 19th century impressionism with a sepia color palette.
Like with many psychedelics, my social inhibitions were lowered. I walked past a group of kids hanging out and smoking weed by the side of the road, and instead of ignoring them like I usually would, I made eye contact, waved and said hello, and we had a little friendly exchange. It was heartwarming to have some small kinship with these complete strangers, with whom I probably had very little in common. I had a fleeting vision in which I saw humanity as one continuous ocean, and death as waves lapping over the shore.
T+0:40 -- I get back home, and play the piano for about twenty minutes, jamming in a spontaneous stream-of-consciousness flow. I played with spacey, trippy, almost tongue-in-cheek chords: a fitting soundtrack to the living animation that I had entered.
T+1:00 -- I'm now peaking, and I head into my bedroom. When I check the time, I'm startled that only an hour has passed. By this point, the full character of the drug is apparent. My mood was simply cheerful and lucid; for contrast, I find that 4-AcO-DMT presents some combination of awe, terror, and rapture; 4-AcO-DET creates a dreamlike, distant apathy. Beside the cartoon effect, open-eye visuals were minimal, consisting of only some minor pareidolia, and I didn't notice anything in the way of closed-eye visuals or auditory hallucinations.
However, by far the most bizarre and memorable aspect of the entire trip was the bodily sensation -- or lack thereof, I should say. From head to toe, simply put, I was numb. When I closed my lips, or touched my tongue against my palate, I felt like I'd just gotten a shot of novocaine at the dentist. If I crossed my legs, I couldn't feel them pressed up against one another. My whole body felt like it was made of clay, which was especially true if I tried to get up and walk around, as movement was somewhat stiff and effortful. While I enjoyed the music I was listening to (Savant - Vario), my hearing was slightly muffled, as if there were cotton balls stuffed in my ears -- I recall something similar happening on 1P-LSD.
T+1:05 -- I take my blood pressure, which reads 138/78 (typically I'm around 110/70). Significantly elevated, but nothing terribly alarming. My pulse had risen from its usual ~80 to 88.
I continue to enjoy the music, while deeply contemplating the nature of the drug, and my relationship with psychedelics in general.
T+1:50 -- I notice that the effect is now slightly diminished. It very smoothly and gradually wanes over the next few hours.
T+6:00 -- As I'm lying in bed to fall asleep, I'm pleasantly surprised by some nice closed-eye visuals: colorful, three-dimensional, abstract geometry. Apparently the hypnagogic state helped to kick in the visual aspect of 4-HO-MPT for me, despite having come down for the most part.
T+~12:00 -- I wake up having slept reasonably well, however I have a sore neck, apparently from sleeping in a poor posture. My body still feels partially numb in the morning. It could be a coincidence, but I can't help but wonder if the analgesic aspect of the drug blunted the physical sensations that would have otherwise signaled me to properly adjust my bodily position during the night. No other negative after-effects persist into the following day.
Summary
In retrospect, after now trying every combination of methyl, ethyl, and propyl 4-substituted tryptamines, I'm led to conclude that extending the alkyl chains on the nitrogen tail seems to have a largely subtractive effect, with the dimethyl substitution having more or less the full spectrum of activity, and bulkier molecules being more selective in various ways. However, I should stress that this is not to say that psilocin is the superior drug, because sometimes these subtractions are very useful. For example, the subdued emotional tone of 4-AcO-DET offers a fascinating opportunity to experience its powerful mind-bending and sensory effects in a rather calm and objective way. The methyl-propyl substitution is a stencil which occludes quite a bit, but what does manage to shine through is very cerebral, as illustrated by the visual aspects, which were't strictly visible, but simply known for no apparent reason. However, 4-HO-MPT does introduce something completely unexpected for me, which is an anaesthetic numbing and motor paralysis.
I think 4-HO-MPT's cerebral focus and cheerful, colorful mood could make for a potentially fantastic trip at higher dosages, but at 26 mg, I found it a bit lacking. I suspect that I'd probably need at least 50 mg, if not more, to really push the psychedelia to a point of satisfying fullness. I'd love to explore the substance at higher dosages, but I have a couple concerns about that. First, the bodily anaesthesia was already quite strong, and frankly I found it unpleasant as it was, let alone at double the dose. Second, I'm uncertain how the hypertension will scale with increasing dosage. If this compound had a more thorough history of human use with a reassuring safety record, I would be much more adventuresome about it, but I'm not one to play guinea pig, so I take these physical factors seriously. I think, if I continue to experiment, I will push forward in small increments, perhaps 5 milligrams at a time.
Until then, I eagerly await any forthcoming reports on the drug from other psychonauts. Stay safe and have fun!
substancecode_4hommt
substancecode_tryptamines
explevel_firsttime
roacode_oral
exptype_positive
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This one really does hold a special place in my heart... and I really am increasingly thinking that it really is related to that dissociative psychedelic effect that I and others seem to consistently get. I really can't wait to see it be explored a bit more thoroughly....
