Lacquerman Steve
Greenlighter
- Joined
- Apr 23, 2016
- Messages
- 45
A question for those using Melanotan II:
Most of what I've read about MT II suggests that a "normal" dosing schedule is .5mg/day for about 2 weeks, then .5mg/wk for tan maintenance. Then, at about day 5, begin adding UV dosing (sun tanning, whether in a tanning bed/booth or in natural sun, to "develop" the melanin crystals and create a nice, dark bronze tan). I've also read that MT II has a biological half-life of 33 hours or so - using that number, I see that the "normal" dosing schedule results in a slow buildup of MT II over two weeks to a near steady-state range of 0.76mg(pre dose) to 1.26mg(post dose) every day.
The reason for waiting 5 days to commence UV dosing seems to be twofold - first, it takes a little time to make new melanin after introduction of MT II, and second, once UV dosing starts, it develops(i.e., darkens/"bronzes") the melanin that has already formed... and then the developed melanin begins to inhibit the development of subsequently formed melanin.
So... my question: Given the dynamics of tanning and its dependence on / reaction to UV exposure, is frontloading still a bad idea with respect to MT II? I mean, it looks like the "normal" dosing schedule is a frontloaded schedule anyway... I don't know if there is a "right" answer here, I'm just interested in opinions, observations and experiences...
In any case, I'll find out soon enough - based on the half-life and accumulation calcs I did, I decided to frontload MT II at 1.25mg, then finish the first week at .25mg/day, then going to .25/wk for maintenance, with UV dosing beginning on day 3.
(FWIW, I'm injecting subQ, not IM or IV. I experienced one NRB (no-reason boner) along with much yawning and stretching about 4 hours after the first dose. None of that since (this is day 3), but appetite is suppressed somewhat, and I am feeling slightly more energetic overall. Also, my vision actually seems slightly improved, in contrast to all reports I've seen of vision sides. I never experienced any nausea at any time except when a needle was actually in me (which is my normal reaction to any hypodermic needle...))
Most of what I've read about MT II suggests that a "normal" dosing schedule is .5mg/day for about 2 weeks, then .5mg/wk for tan maintenance. Then, at about day 5, begin adding UV dosing (sun tanning, whether in a tanning bed/booth or in natural sun, to "develop" the melanin crystals and create a nice, dark bronze tan). I've also read that MT II has a biological half-life of 33 hours or so - using that number, I see that the "normal" dosing schedule results in a slow buildup of MT II over two weeks to a near steady-state range of 0.76mg(pre dose) to 1.26mg(post dose) every day.
The reason for waiting 5 days to commence UV dosing seems to be twofold - first, it takes a little time to make new melanin after introduction of MT II, and second, once UV dosing starts, it develops(i.e., darkens/"bronzes") the melanin that has already formed... and then the developed melanin begins to inhibit the development of subsequently formed melanin.
So... my question: Given the dynamics of tanning and its dependence on / reaction to UV exposure, is frontloading still a bad idea with respect to MT II? I mean, it looks like the "normal" dosing schedule is a frontloaded schedule anyway... I don't know if there is a "right" answer here, I'm just interested in opinions, observations and experiences...
In any case, I'll find out soon enough - based on the half-life and accumulation calcs I did, I decided to frontload MT II at 1.25mg, then finish the first week at .25mg/day, then going to .25/wk for maintenance, with UV dosing beginning on day 3.
(FWIW, I'm injecting subQ, not IM or IV. I experienced one NRB (no-reason boner) along with much yawning and stretching about 4 hours after the first dose. None of that since (this is day 3), but appetite is suppressed somewhat, and I am feeling slightly more energetic overall. Also, my vision actually seems slightly improved, in contrast to all reports I've seen of vision sides. I never experienced any nausea at any time except when a needle was actually in me (which is my normal reaction to any hypodermic needle...))
