Can't say i know many stories of people coming of methadone.
The question is what causes the withdrawals and the sickness of addiction i.e. the anxiety, discomfort and pain that drive us to use. I know people would argue that we're chasing the high but I would argue we're chasing a life free of pain (with a bit of fun thrown in). Its a question of pain relief hence why most people accept the methadone program because it avoids most of the pain that we've suffered when going straight.
As many in aus:drugs will note I have a fairly radical theory on the root cause of addiction i.e the chemicals that cause it and how they are pretty much the same chemicals in play when we're going through "withdrawals" which is a fairly big misnomer in my theory.
See opioids, opiates and pretty much anything that makes it through the blood brain barrier freaks the brain out into activating this thing called TLR4 - Toll Like Receptors (number 4). TLR4 when its turned on makes these toxic chemicals that are responsible for pretty much most of the symptoms you have when you feel sick i.e. headaches, joint pain, muscle/tissue pain, diarrhoea, fevers and so on are all caused by a class of chemicals called proinflammatory cytokines. All of these reactions are the very same that we experience we stop taking heroin/methadone/suboxone/oxy - why because these drugs are activating TLR4 either directly or indirectly. See you have to imagine our body full of opiate receptors. They aren't neccessarily there for opiates but they and the cytokines are battling to bind to them.
So the pain and discomfort of withdrawals is about the absence of opiates which allows these cytokines to flood our body especially the receptors in our brain the Ku an Mu that are responsible for the pain relieving effects we feel from opiates. Its the literal equivalent of pouring acid onto the pleasure centre of our brain.
That is why once I have the funds I plan to buy a drug that disables TLR4 and see if I can get of methadone and stop taking opiates altogether (i have already quit all other drugs). The trials of this drug (already used for other purposes) have shown great results in helping addicts quit taking meth, opiates and even alcohol which in my mind is validation of the theory I've espoused.
So on that note make sure you have a clear program with your doctor about dealing with health issues. Eat healthy (something that I have ignored to my recent peril), and get exercise whilst making sure you find some a new non-drug activity to work on or do that you enjoy.
That said I would suggest you look at trying ibudilast. This is the drug that deactivates TLR4 which due to physical and emotional abuse i believe is malfunctioning (from when you were in the womb and in early childhood).
For further reading -
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783351/ The “Toll” of Opioid-Induced Glial Activation: Improving the Clinical Efficacy of Opioids by Targeting Glia
