pharmacokenitics
Greenlighter
- Joined
- Jan 25, 2017
- Messages
- 6
This will be more of a timeline of withdrawal and what I have done to mitigate the worst of the symptoms. The information contained within works for me, it could be deadly for you. Use extreme caution and do not take this method lightly. Sadly this will require a decent doctor willing to prescribe you drugs that will help you sleep, help with the restless legs, general malaise and mud butt. The single most important thing you MUST not do while using these medications is use opioids. The likely hood of death via respiratory depression is VERY HIGH! DO NOT USE ANY OPIOIDS WHILE USING THIS METHOD!
[This is for ease of use. Here is the list of medications I will be using so you don't have to scroll around:
Clonazepam (2-4mg a day)
Any benzodiazepine will work. The longer acting the better. Diazepam, Diclazepam, Flubromazepam are good alternatives.
Etizolam (easiest to obtain for most since you can buy it online currently) and lorazepam will work but have short half lifes. You are looking for long half lives with (in order of importance) anxiolytic, muscle relaxant and hypnotic properties. Here is a link to Wikipedia that may help you: https://en.m.wikipedia.org/wiki/List_of_benzodiazepines
Clonadine (.1-.2mg a day.....Yes that is one tenth of a milligram)
Gabapentin (100mg at a time over a period of 5 hours the total dose is 500mg a day)
Magnesium glycinate or glucoheptonate.
Make sure you don't just buy off the shelf magnesium pills as the oxide, citrate or most other forms have very low bioavailability, I'm talking less than 10% in some cases. Talk to a pharmacist, they will be able to help you.
Naproxen (also known as Aleve). Don't buy the brand name shit. Naproxen is naproxen, it doesn't matter who makes it. The brand name Aleve is marked up significantly. They come in 220mg pill forms. If you get a prescription from a doctor I believe the pharmacy dispenses 500+mg pills so it is realatively safe to take 440mg at a time (2 pills). NOTE: Naproxen lasts for 24 hours! Only take 440mg ONCE a day! You can split up the dose so as to take 1 pill at say 10am and another pill at 2pm.....This may be ideal if you have gabapentin as I will explain below.
Methocarbamol. This is a skeletal muscle relaxant. Not totally necessary but can help. It is always paired with either ibprofren (advil) or acetomenaphen (Tylenol). Go for the stuff with acetomenaphen if you are going to be using naproxen. The reason for this is both naproxen and ibprofren are both NSAIDs and it is bad for your kidneys to take too much, which you will if you use both naproxen and ibprofren. Same as naproxen, don't buy the brand name shit (robaxacet) buy the off brand. Save some moneys.
Dimenhydrinate (gravol) Just buy like 30 pills at 50mg each. Again, don't buy brand name gravol, dimenhydranate is dimenhydranate. Save your money! This is especially important if you don't plan on smoking any weed as it is an anti-emetic. Meaning it should help with naseua. It also is sedating so it can be combined with clonadine and clonazepam to help you sleep. BE WARNED! HIGH DOSES OF DIMENHYDRINATE WILL MAKE YOU HALLUCINATE AND IT IS NOT FUN!! Stick to a max of 150mg and no more. Normal dose is 50mg. Trust me, you don't want to trip on this with a healthy mind/body, tripping on this while in withdrawal will give a new meaning to hell on earth. I rarely take more than 100mg on a good day.
A good multivitamin. Take at least twice what the bottle tells you once a day. You will be losing a lot of nutrients in the coming days and this should help accelerate the healing process.
Cannabis. This is personal preference, if you aren't a weed smoker already this part should be mostly ignored unless you have a friend that does smoke weed and can show you how LITTLE you need to smoke so as to not have a bad time. For me personally this stuff is awesome for withdrawal. I often get a boost of energy and it seems to help with all the symptoms except mud butt.
I got a bunch of those Ensure breakfast in a bottle things. I drink one before my first gabapentin dose as I explain below. It is also about the only thing food wise I can stomach during this time. Get the high protein ones. Doesn't have to be ensure but avoid the special k brand cereal ones. They don't seem to be as nutritious.]
Okay, onto the methods and experiences:
I had been using either poppy seed tea or poppy pod tea everyday for the last 2 years straight. At the end I was using about 1.5kg of VERY good seeds or about 50-75 pods. 160mg of oxycodone would be just enough to make me feel kind of high. I finally decided enough was enough. It is truely a wonder at how it ruins your life in the most subtle of ways. I stole pods from gardens in the summer and purchased seeds from a local bulk shop 55kg at a time. The seeds were costing me about $700 a month, not counting all the 2l bottles I had to buy to do the washes....I estimate that was another $100 a month. I have a job and good friends and a place to live....Yet I still used. I have missed out on potential relationships, potential experiences etc. etc. etc. I digress....
So cold turkeys. Currently I am on day 7. My last tea was Thursday the 19th at 5am. It is Wednesday the 25th at 8am today.
Day 1 (Thursday the 19th): I split on work after making a dumb mistake and nearly killed myself for it. I realized something had to change, and that change was to stop using opium. I nutted up and went and saw my doctor (who just so happens to be an addictions specialist) and told him everything. Only two other people knew at this point (not including my amazing boss/friend) and the fact that I was hiding it from my boss created a lot of guilt. Anyways...,.
My doctor prescribed me 2mg clonazepam twice a day, .1mg clonadine twice a day and gabapentin 100mg 5 times a day. I personally obtained about 100mg of loperamide, magnesium glucoheptonate (the glucoheptonate has a bioavailability that is much much much higher than any magnesium oxide, citrate or any other type of magnesium you can buy off the shelf. Ask a pharmacist....They should be able to help you. There is a liquid form too. I also bought a giant bottle of multivitamins and am currently taking 3 times what the bottle recommends. I also purchased a ton of dimenhydrinate (brand name is gravol but don't buy actual gravol buy the off brand stuff. Money can be better spent on other things rather than just a name. After all, dimenhydrinate is dimenhydrinate.)
I also purchased some naproxen and methocarbamol. Methocarbamol is in robaxacet but of course....Don't buy robaxacet, get the off brand stuff to save money.
The first day was fine as I was still stewing in opium alkaloids.
Day 2 (Friday the 20th....One month till my 30th birthday): Things start going downhill. It has been 24hrs from my last dose and my stomach has turned to liquid. I let my body do it's thing then I take 6mg of loperamide. My goal here is to have ONE bowl movement everyday or every other day. The reason for this is so I don't have to replenish lost nutrients or electrolytes and obviously it is far more comfortable. I start getting these weird shivers all over my body. Not like I'm cold....Like they are bad feeling. This is an overcompensation by my brain/body due to the years of norepinephrine suppression. It is going to get a lot worse very soon. This is what the clonadine is for. It binds to a2 receptors in the brain which decrease peripheral vascular resistance thus lowering blood pressure. This also binds to presynaptic a2 receptors in the brainstem which decreases presynaptic calcium levels thus inhibiting norepinephrine release. I am starting to feel incredibly fatigued, like I could sleep for weeks but that isn't gonna be easy. I spent most of my day preparing for tomorrow. Cleaning, getting things ready for being bed ridden. It isn't easy but I HAVE to do it in order to not lose my shit halfway through this. No sleep today.
Day 3 (Saturday the 21st): Today sucks. Everything hurts, my brain is screaming for tea and my stomach is doing backflips. I've thrown up a few times in the night and the diahrea still broke through my previous loperamide dose. Today is the day I go all out with comfort meds. .1mg clonadine to start alongside some naproxen. I have no tolerance (well very little, I used to take both of these drugs but it has been at least 8 months since I have) to benzodiazepines or gabapentin. I take 2mg clonazepam sublingually, and begin my gabapentin dosing. I also take 500mg acetomenaphen and methocarbamol. I forgot to mention but I also took another 6mg of loperamide to ease the stomach cramps. I don't want to take much more than that because I am looking to withdraw completely and loperamide WILL cross the blood brain barrier if taken in high enough doses.
[Side note on gabapentin: this is a weird drug. If you take say 500mg all at once your body is not going to absorb most of it. The key here is staggered dosing with protein. Here is how I use it and this is from years of reading people's experiences on bluelight. First I drink a protein drink. Ensure is the brand. Then I take 100mg and note the time. Every 45 minutes for the next 4 hours I will take 100mg. When I take the second 100mg dose I take a naproxen. This supposedly helps absorption but it may be bullshit. In the next hour and a half I take another 200mg gabapentin. When I take my last 100mg I also take my last 220mg naproxen. This will equal 500mg of gabapentin and 440mg of naproxen in 5 hours time, and trust me.....This is by far the best way to take gabapentin in my experience.]
Now I suffer haha. Actually it isn't SO bad. I cold turkeyed a year long 16mg Suboxone run without ANY meds. This is a cake walk comparatively. I spend my day just trying to take my mind off the ick. Smoke some weed and just watch some TV. I downloaded black mirror so I am working my way through that.....Bawling my eyes out at certain points as my emotions are no longer dulled by opium. I got about 4 hours of sleep this day, surprisingly.
Day 4 (Sunday the 22nd): I dose everything the exact same as the day before except the loperamide. Untill I start getting real bad mud butt I'm gonna hold off. Today I'm in a daze from all the gabaergic drugs in my system but it is preferable to feeling the full brunt of withdrawal. Not much has changed symptom wise but I know tomorrow will be better than today. The timeline for opium withdrawal is extended compared to short acting opioids like heroin or oxycodone. It isn't as intense but it still sucks a thousand bags of firery rotten dicks.
Day 5 (Monday the 23rd): Slept a solid 6 hours last night since I ended up cheating a bit and took an extra 1mg of clonazepam before I went to bed. I feel better today but I still have a ways to go. I was able to play some hearts of iron 4 today for the first time since I bought it. Poland is nothing more than lebensraum for the great Aryan race. (I joke, I know Hitler was evil incarnate and what he did in the east was a tragedy the likes of which is rarely seen in this world. I have no love for facism or anti-Semitic people, I just like to role play) The chills and general malaise are slowly going away. I get bursts of energy and a general feeling of well being but it goes away fast. This is good though...it shows I am making progress. I slept around 5 hrs this night.
Day 6 (Tuesday the 24th) I wake up and am able to do things. I did dishes, laundry and even took my doggo for a short walk. I still feel like ass but it is important to get moving as soon as possible. I plan on going swimming in a few days just to get my endorphins going. I mostly played hearts of iron for most of the day, smoking a lot of weed. A great day for the world as the third Reich is crumbling under the combined weight of the Soviet Juggernaut and the ungodly and seemingly impossible production capabilities of the United States. Lebensraum is nothing more than a faint memory in the German people's minds as the Soviets have finally crossed into Germany proper. I am feeling better and better by the day, although I know I'm not out of the woods yet. This night I slept for 14 hours! Thank god for sedative hypnotics.
I am currently on day 7 and debating on going swimming. It is an hour of driving but it may be worth it. I dunno yet. We will see.
I walked my dog but no swimming because of lack of funds. It is 130am right now and I am wide awake. Most likely because I went to sleep around 730pm. 6 hours ain't bad but fuck me I hate being awake at this time. I am certainly constipated right now due to the loperamide which is bothering me. I won't be taking anymore of that till I have another bowel movement. I may have over done it on that end. This is obviously going to turn more into a journal than a conversation which is okay I guess. I hope some of this helps someone somewhere sometime!
Day 8 (Thursday the 26th): I am feeling pretty down today. I assume this is the start of PAWS. I had posted a bunch of stuff on a couple of Reddit subs in hopes of garnering some responses but the one post that was approved was up for 2 days and no comments, while the other post was never approved. Kinda depressing to be honest. I put a lot of effort into the above method but I guess I am no doctor so perhaps I will delete this too. There are better and smarter people out there than me who can create much better and easier to understand information than I ever could. To think otherwise is just delusional. Just lonely now, which is what drove me to this shit in the first place. It's gonna be really hard not to use today.
[This is for ease of use. Here is the list of medications I will be using so you don't have to scroll around:
Clonazepam (2-4mg a day)
Any benzodiazepine will work. The longer acting the better. Diazepam, Diclazepam, Flubromazepam are good alternatives.
Etizolam (easiest to obtain for most since you can buy it online currently) and lorazepam will work but have short half lifes. You are looking for long half lives with (in order of importance) anxiolytic, muscle relaxant and hypnotic properties. Here is a link to Wikipedia that may help you: https://en.m.wikipedia.org/wiki/List_of_benzodiazepines
Clonadine (.1-.2mg a day.....Yes that is one tenth of a milligram)
Gabapentin (100mg at a time over a period of 5 hours the total dose is 500mg a day)
Magnesium glycinate or glucoheptonate.
Make sure you don't just buy off the shelf magnesium pills as the oxide, citrate or most other forms have very low bioavailability, I'm talking less than 10% in some cases. Talk to a pharmacist, they will be able to help you.
Naproxen (also known as Aleve). Don't buy the brand name shit. Naproxen is naproxen, it doesn't matter who makes it. The brand name Aleve is marked up significantly. They come in 220mg pill forms. If you get a prescription from a doctor I believe the pharmacy dispenses 500+mg pills so it is realatively safe to take 440mg at a time (2 pills). NOTE: Naproxen lasts for 24 hours! Only take 440mg ONCE a day! You can split up the dose so as to take 1 pill at say 10am and another pill at 2pm.....This may be ideal if you have gabapentin as I will explain below.
Methocarbamol. This is a skeletal muscle relaxant. Not totally necessary but can help. It is always paired with either ibprofren (advil) or acetomenaphen (Tylenol). Go for the stuff with acetomenaphen if you are going to be using naproxen. The reason for this is both naproxen and ibprofren are both NSAIDs and it is bad for your kidneys to take too much, which you will if you use both naproxen and ibprofren. Same as naproxen, don't buy the brand name shit (robaxacet) buy the off brand. Save some moneys.
Dimenhydrinate (gravol) Just buy like 30 pills at 50mg each. Again, don't buy brand name gravol, dimenhydranate is dimenhydranate. Save your money! This is especially important if you don't plan on smoking any weed as it is an anti-emetic. Meaning it should help with naseua. It also is sedating so it can be combined with clonadine and clonazepam to help you sleep. BE WARNED! HIGH DOSES OF DIMENHYDRINATE WILL MAKE YOU HALLUCINATE AND IT IS NOT FUN!! Stick to a max of 150mg and no more. Normal dose is 50mg. Trust me, you don't want to trip on this with a healthy mind/body, tripping on this while in withdrawal will give a new meaning to hell on earth. I rarely take more than 100mg on a good day.
A good multivitamin. Take at least twice what the bottle tells you once a day. You will be losing a lot of nutrients in the coming days and this should help accelerate the healing process.
Cannabis. This is personal preference, if you aren't a weed smoker already this part should be mostly ignored unless you have a friend that does smoke weed and can show you how LITTLE you need to smoke so as to not have a bad time. For me personally this stuff is awesome for withdrawal. I often get a boost of energy and it seems to help with all the symptoms except mud butt.
I got a bunch of those Ensure breakfast in a bottle things. I drink one before my first gabapentin dose as I explain below. It is also about the only thing food wise I can stomach during this time. Get the high protein ones. Doesn't have to be ensure but avoid the special k brand cereal ones. They don't seem to be as nutritious.]
Okay, onto the methods and experiences:
I had been using either poppy seed tea or poppy pod tea everyday for the last 2 years straight. At the end I was using about 1.5kg of VERY good seeds or about 50-75 pods. 160mg of oxycodone would be just enough to make me feel kind of high. I finally decided enough was enough. It is truely a wonder at how it ruins your life in the most subtle of ways. I stole pods from gardens in the summer and purchased seeds from a local bulk shop 55kg at a time. The seeds were costing me about $700 a month, not counting all the 2l bottles I had to buy to do the washes....I estimate that was another $100 a month. I have a job and good friends and a place to live....Yet I still used. I have missed out on potential relationships, potential experiences etc. etc. etc. I digress....
So cold turkeys. Currently I am on day 7. My last tea was Thursday the 19th at 5am. It is Wednesday the 25th at 8am today.
Day 1 (Thursday the 19th): I split on work after making a dumb mistake and nearly killed myself for it. I realized something had to change, and that change was to stop using opium. I nutted up and went and saw my doctor (who just so happens to be an addictions specialist) and told him everything. Only two other people knew at this point (not including my amazing boss/friend) and the fact that I was hiding it from my boss created a lot of guilt. Anyways...,.
My doctor prescribed me 2mg clonazepam twice a day, .1mg clonadine twice a day and gabapentin 100mg 5 times a day. I personally obtained about 100mg of loperamide, magnesium glucoheptonate (the glucoheptonate has a bioavailability that is much much much higher than any magnesium oxide, citrate or any other type of magnesium you can buy off the shelf. Ask a pharmacist....They should be able to help you. There is a liquid form too. I also bought a giant bottle of multivitamins and am currently taking 3 times what the bottle recommends. I also purchased a ton of dimenhydrinate (brand name is gravol but don't buy actual gravol buy the off brand stuff. Money can be better spent on other things rather than just a name. After all, dimenhydrinate is dimenhydrinate.)
I also purchased some naproxen and methocarbamol. Methocarbamol is in robaxacet but of course....Don't buy robaxacet, get the off brand stuff to save money.
The first day was fine as I was still stewing in opium alkaloids.
Day 2 (Friday the 20th....One month till my 30th birthday): Things start going downhill. It has been 24hrs from my last dose and my stomach has turned to liquid. I let my body do it's thing then I take 6mg of loperamide. My goal here is to have ONE bowl movement everyday or every other day. The reason for this is so I don't have to replenish lost nutrients or electrolytes and obviously it is far more comfortable. I start getting these weird shivers all over my body. Not like I'm cold....Like they are bad feeling. This is an overcompensation by my brain/body due to the years of norepinephrine suppression. It is going to get a lot worse very soon. This is what the clonadine is for. It binds to a2 receptors in the brain which decrease peripheral vascular resistance thus lowering blood pressure. This also binds to presynaptic a2 receptors in the brainstem which decreases presynaptic calcium levels thus inhibiting norepinephrine release. I am starting to feel incredibly fatigued, like I could sleep for weeks but that isn't gonna be easy. I spent most of my day preparing for tomorrow. Cleaning, getting things ready for being bed ridden. It isn't easy but I HAVE to do it in order to not lose my shit halfway through this. No sleep today.
Day 3 (Saturday the 21st): Today sucks. Everything hurts, my brain is screaming for tea and my stomach is doing backflips. I've thrown up a few times in the night and the diahrea still broke through my previous loperamide dose. Today is the day I go all out with comfort meds. .1mg clonadine to start alongside some naproxen. I have no tolerance (well very little, I used to take both of these drugs but it has been at least 8 months since I have) to benzodiazepines or gabapentin. I take 2mg clonazepam sublingually, and begin my gabapentin dosing. I also take 500mg acetomenaphen and methocarbamol. I forgot to mention but I also took another 6mg of loperamide to ease the stomach cramps. I don't want to take much more than that because I am looking to withdraw completely and loperamide WILL cross the blood brain barrier if taken in high enough doses.
[Side note on gabapentin: this is a weird drug. If you take say 500mg all at once your body is not going to absorb most of it. The key here is staggered dosing with protein. Here is how I use it and this is from years of reading people's experiences on bluelight. First I drink a protein drink. Ensure is the brand. Then I take 100mg and note the time. Every 45 minutes for the next 4 hours I will take 100mg. When I take the second 100mg dose I take a naproxen. This supposedly helps absorption but it may be bullshit. In the next hour and a half I take another 200mg gabapentin. When I take my last 100mg I also take my last 220mg naproxen. This will equal 500mg of gabapentin and 440mg of naproxen in 5 hours time, and trust me.....This is by far the best way to take gabapentin in my experience.]
Now I suffer haha. Actually it isn't SO bad. I cold turkeyed a year long 16mg Suboxone run without ANY meds. This is a cake walk comparatively. I spend my day just trying to take my mind off the ick. Smoke some weed and just watch some TV. I downloaded black mirror so I am working my way through that.....Bawling my eyes out at certain points as my emotions are no longer dulled by opium. I got about 4 hours of sleep this day, surprisingly.
Day 4 (Sunday the 22nd): I dose everything the exact same as the day before except the loperamide. Untill I start getting real bad mud butt I'm gonna hold off. Today I'm in a daze from all the gabaergic drugs in my system but it is preferable to feeling the full brunt of withdrawal. Not much has changed symptom wise but I know tomorrow will be better than today. The timeline for opium withdrawal is extended compared to short acting opioids like heroin or oxycodone. It isn't as intense but it still sucks a thousand bags of firery rotten dicks.
Day 5 (Monday the 23rd): Slept a solid 6 hours last night since I ended up cheating a bit and took an extra 1mg of clonazepam before I went to bed. I feel better today but I still have a ways to go. I was able to play some hearts of iron 4 today for the first time since I bought it. Poland is nothing more than lebensraum for the great Aryan race. (I joke, I know Hitler was evil incarnate and what he did in the east was a tragedy the likes of which is rarely seen in this world. I have no love for facism or anti-Semitic people, I just like to role play) The chills and general malaise are slowly going away. I get bursts of energy and a general feeling of well being but it goes away fast. This is good though...it shows I am making progress. I slept around 5 hrs this night.
Day 6 (Tuesday the 24th) I wake up and am able to do things. I did dishes, laundry and even took my doggo for a short walk. I still feel like ass but it is important to get moving as soon as possible. I plan on going swimming in a few days just to get my endorphins going. I mostly played hearts of iron for most of the day, smoking a lot of weed. A great day for the world as the third Reich is crumbling under the combined weight of the Soviet Juggernaut and the ungodly and seemingly impossible production capabilities of the United States. Lebensraum is nothing more than a faint memory in the German people's minds as the Soviets have finally crossed into Germany proper. I am feeling better and better by the day, although I know I'm not out of the woods yet. This night I slept for 14 hours! Thank god for sedative hypnotics.
I am currently on day 7 and debating on going swimming. It is an hour of driving but it may be worth it. I dunno yet. We will see.
I walked my dog but no swimming because of lack of funds. It is 130am right now and I am wide awake. Most likely because I went to sleep around 730pm. 6 hours ain't bad but fuck me I hate being awake at this time. I am certainly constipated right now due to the loperamide which is bothering me. I won't be taking anymore of that till I have another bowel movement. I may have over done it on that end. This is obviously going to turn more into a journal than a conversation which is okay I guess. I hope some of this helps someone somewhere sometime!
Day 8 (Thursday the 26th): I am feeling pretty down today. I assume this is the start of PAWS. I had posted a bunch of stuff on a couple of Reddit subs in hopes of garnering some responses but the one post that was approved was up for 2 days and no comments, while the other post was never approved. Kinda depressing to be honest. I put a lot of effort into the above method but I guess I am no doctor so perhaps I will delete this too. There are better and smarter people out there than me who can create much better and easier to understand information than I ever could. To think otherwise is just delusional. Just lonely now, which is what drove me to this shit in the first place. It's gonna be really hard not to use today.
Last edited:
