The only thing that will cause pwd, is taking suboxone too soon after you dosed a full agonist opioid previously. And vice verca, taking a full agonist opioid (Heroin) after you dosed suboxone previously will not cause pwd, it may have a blocking effect on your dose though. Nothing else can cause pwd, however that's not to say that suboxone can be taken with anything else. There are alot of drugs that have a major interactions with buprenorphine and nalaxone.. Anything that depresses the CNS will be listed as a 'major interaction', i.e. Alprazolam, alcohol.
I think they synergize well together, read the first post in the link I provided..
- Hopeless Soul