• TDS Moderators: AlphaMethylPhenyl | Eligiu | deficiT

⫸STAFF⫷ A place to keep commonly used links Vs sik & tired of looking for this

updated links when possible. Crazy format is due to originally being behind the scenes. Anybody has good links please add.
 
Methadone, a potent opioid agonist, has many characteristics that make it useful for the treatment of pain when continuous opioid analgesia is indicated. Although available for decades, its use has gained renewed interest due to its low cost and potential activity in neuropathic pain syndromes. Unlike morphine, methadone is a racemic mix; one stereoisomer acts as a NMDA receptor antagonist, the other is a mu-agonist opioid. The NMDA mechanism plays an important role in the prevention of opioid tolerance, potentiation of opioid effects, and efficacy for neuropathic pain syndromes, although this latter impression is largely anecdotal.

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Fast Fact and Concept #75: Methadone for Pain
 
Liver function and Opioids



I see you guys unapproved this again, I searched for it on google and the was able to read and post for some reason. This thread was originally kept just for TDS staff as a place to share and easily find commonly used info.
 
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