THIS ONLY MY ANECDOTAL EXPERIENCE, NOT OFFICIAL INFORMATION. THERE IS CURRENTLY NO RESEARCH AND NO OFFICIAL DATA ON THIS DRUG, SO AVOID USING IT AT ALL COSTS AND STICK WITH WELL KNOWN PRESCRPTION BENZODIAZEPINES. I HAVE HAD NEAR-DEATH EXPERIENCES WITH RC DEPRESSANTS, AND I SUGGEST YOU FOLLOW MY ADVICE. YOU HAVE BEEN WARNED.
Flubromazolam, the triazolo analogue of Flubromazepam, a less potent, but longer lasting benzodiazepine.
There is zero legitimate information on this drug. Not even a Wikipedia page.
POTENCY AND ONSET OF ACTION
There is no official information on the potency of this benzo. So all I can share is my own experience.
From my comparison, when consumed sublingually for 20 mins and then swallowed the potency is around x4 of Alprazolam. Onset of action is always random, but rapid at the same time. It can take between 1-5hours to kick in, but once it does it's instant. Usually the first effects are strong sedation and amnesic effect (and a blackout in larger doses).
HALF-LIFE AND LENGTH OF EFFECTS
After very extensive and shady research, I have discovered that it has a 106 hour half-life, that's nothing compared to it's older brother Flubromazepam's 220 hour half-life.
Length of effects largely depends on the dosage.
0.25mg - 0.5mg - effects last for around 4-6 hours, and vanish very quickly.
Up to 1mg - Effects last up to 24 hours, with a noticeable "after glow"
2.5mg+ - Effects last for up to 3 days, followed by Amnesic after-effect
4mg + - Effects last for up to 3 days, followed by severe cognitive impairment and memory loss.
THE EFFECTS
Doses below 0.5mg are usually a very sedative and mildly euphoric benzodiazepine effect, like a rough version of Nitrazepam.
Doses above 0.5mg usually cause blackouts, memory loss, neurotoxicity and a bunch of other side effects.
I have personally consumed 10mg (equivalent to 800mg diazepam, yeah, I have enormous tolerance) and had a 3-day black out followed by extreme withdrawal symptoms.
TOXICITY, SIDE-EFFECTS, TOLERANCE, SUB-UNIT TOLERANCE AND DEPENDNACE
Thought to be just as toxic (possibly more) as Triazolam, and neurotoxicity is obvious at larger doses.
Side-effects:
0.25mg - 0.5mg Mild respiratory depression and cognitive impairment.
1mg - Respiratory depression and muscle weakness, severe cognitive impairment.
2.5mg and above - Severe respiratory depression, chest pain, heart palpitations and even stomach related problems.
Sub-unit tolerance - Instant and becomes almost permanent with repeated use, only affects a1 and a5 sub-units, and has little binding affinity for the a3 and a2 sub-units, very little cross-tolerance with Clonazepam (confirmed by personal experience). Possibly affects b2 sub-units, however, I have not experienced cross-tolerance with barbiturates, so this is unconfirmed.
Tolerance - GABA-A tolerance builds after using it only 2 times, which immediately leads to withdrawal.
SUB-UNIT SELECTIVITY
Highly selective for the a1 and a5 sub-units at the GABA-A receptor. Speculation, but this is the only way I can explain the sedative, amnesic and cognitive impairing effects of this benzo.
(Speculation) Possisble selectivity for beta(barbiturate)-subunits, as proven by respiratory depression and chest pain.
CONCLUSION
Flubromazolam is a slightly more toxic, long-lasting version of Triazolam. Certainly more recreational. I would avoid this benzo as sub-unit tolerance takes a VERY long time to reset or possibly never resets with repeated use.
Flubromazolam, the triazolo analogue of Flubromazepam, a less potent, but longer lasting benzodiazepine.
There is zero legitimate information on this drug. Not even a Wikipedia page.
POTENCY AND ONSET OF ACTION
There is no official information on the potency of this benzo. So all I can share is my own experience.
From my comparison, when consumed sublingually for 20 mins and then swallowed the potency is around x4 of Alprazolam. Onset of action is always random, but rapid at the same time. It can take between 1-5hours to kick in, but once it does it's instant. Usually the first effects are strong sedation and amnesic effect (and a blackout in larger doses).
HALF-LIFE AND LENGTH OF EFFECTS
After very extensive and shady research, I have discovered that it has a 106 hour half-life, that's nothing compared to it's older brother Flubromazepam's 220 hour half-life.
Length of effects largely depends on the dosage.
0.25mg - 0.5mg - effects last for around 4-6 hours, and vanish very quickly.
Up to 1mg - Effects last up to 24 hours, with a noticeable "after glow"
2.5mg+ - Effects last for up to 3 days, followed by Amnesic after-effect
4mg + - Effects last for up to 3 days, followed by severe cognitive impairment and memory loss.
THE EFFECTS
Doses below 0.5mg are usually a very sedative and mildly euphoric benzodiazepine effect, like a rough version of Nitrazepam.
Doses above 0.5mg usually cause blackouts, memory loss, neurotoxicity and a bunch of other side effects.
I have personally consumed 10mg (equivalent to 800mg diazepam, yeah, I have enormous tolerance) and had a 3-day black out followed by extreme withdrawal symptoms.
TOXICITY, SIDE-EFFECTS, TOLERANCE, SUB-UNIT TOLERANCE AND DEPENDNACE
Thought to be just as toxic (possibly more) as Triazolam, and neurotoxicity is obvious at larger doses.
Side-effects:
0.25mg - 0.5mg Mild respiratory depression and cognitive impairment.
1mg - Respiratory depression and muscle weakness, severe cognitive impairment.
2.5mg and above - Severe respiratory depression, chest pain, heart palpitations and even stomach related problems.
Sub-unit tolerance - Instant and becomes almost permanent with repeated use, only affects a1 and a5 sub-units, and has little binding affinity for the a3 and a2 sub-units, very little cross-tolerance with Clonazepam (confirmed by personal experience). Possibly affects b2 sub-units, however, I have not experienced cross-tolerance with barbiturates, so this is unconfirmed.
Tolerance - GABA-A tolerance builds after using it only 2 times, which immediately leads to withdrawal.
SUB-UNIT SELECTIVITY
Highly selective for the a1 and a5 sub-units at the GABA-A receptor. Speculation, but this is the only way I can explain the sedative, amnesic and cognitive impairing effects of this benzo.
(Speculation) Possisble selectivity for beta(barbiturate)-subunits, as proven by respiratory depression and chest pain.
CONCLUSION
Flubromazolam is a slightly more toxic, long-lasting version of Triazolam. Certainly more recreational. I would avoid this benzo as sub-unit tolerance takes a VERY long time to reset or possibly never resets with repeated use.
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