invegascrewed
Greenlighter
- Joined
- Jul 12, 2015
- Messages
- 46
By better- do we know if people get back to their original selves - reading a lot of articles- it seems widespread disconnect of neural networks is observed in short term use, but no body is measuring the withdrawal period to see if people revert back to what is considered baseline normal:
"A 2-week withdrawal is likely not enough to allow medication-induced brain changes to fully revert to a baseline condition. However, the potent rCBF increase observed in the dorsal and ventral striatum by APDs in this study strongly suggested that DA receptors were not blocked by residual medication."
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515723/
"Overall, the current study revealed that short-term antipsychotic treatment in schizophrenia leads to increased regional synchronous neural activity while at the same time causing attenuated functional integration across widely distributed neural networks. "
http://archpsyc.jamanetwork.com/article.aspx?articleid=210850
Assumption is physical effects do disappear after short-term use after discontinuation might indicate things do return to some level of baseline; disappearance of parkinsonism, akathesia, etc. and other physical side effects.
"A 2-week withdrawal is likely not enough to allow medication-induced brain changes to fully revert to a baseline condition. However, the potent rCBF increase observed in the dorsal and ventral striatum by APDs in this study strongly suggested that DA receptors were not blocked by residual medication."
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515723/
"Overall, the current study revealed that short-term antipsychotic treatment in schizophrenia leads to increased regional synchronous neural activity while at the same time causing attenuated functional integration across widely distributed neural networks. "
http://archpsyc.jamanetwork.com/article.aspx?articleid=210850
Assumption is physical effects do disappear after short-term use after discontinuation might indicate things do return to some level of baseline; disappearance of parkinsonism, akathesia, etc. and other physical side effects.