I agree and disagree with that. I see your reluctance for stimulants and CNS depressants as well as opiates. On the other hand SSRI's and SNRI's are relatively new compared to those. Just recently is science able to examine people who have been on such drugs for a lifetime. I understand how the new generation of antidepressants works, but science has never proven that serotonin being absorbed by cells in too large amounts is the cause of depression. They have many indicators, but, like all science it is a theory, and theories are constantly shifting. I have O.C.D., I feel I have to be perfect, I count and divide, multiply everything, many rituals, I had a nervous breakdown my first time in college when I was pre-med because I missed a final. I also have ADD and panic disorder. They are all debilitating. I went through all types of the antidepressants, SSRI, tri, SNRI...they did not work. I could tell they were effecting me, but not in a way that improved my life. I take benzo's for the panic disorder, and take the long term. I take Adderall for the ADD. As far as my OCD, not that I would recommend you do this, I do this on my own, I take opiates. Everyone's brain chemistry is different, this combination has literally saved my life. Basically all of these drugs pose risks, so yes, what does more harm? Your ability to enjoy life, or potential effects? It's awful but sadly many people have to play test monkey until they find something that works. I have taken the benzo class of drugs for 10 years, and I so far have no loss of short term memory. Yet many people do, and quickly. And stimulants are not meant to grow brain cells, they change the chemicals in your brain enhancing chemicals they believe help you concentrate. I know many people who use marijuana, it's legal around here, and it really helps them. So I suppose all I can say is find a balance, and if you meet a shrink who doesn't listen to your valid concerns, maybe it is time for a new one.