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4aco-dmt how to make it stronger?

ros1816

ros1816

Bluelighter
Joined
Mar 11, 2014
Messages
106
I've taken 4aco 8 times in the past 5 months. Ive clearly built a big tolerance to tryptamines on top of an inborn high tolerance. The tolerance would go down a bit with a few months off but will stay with me largely my whole life i reckon

200mg of 4aco fumarate isnt that strong. Its alright tho.

I was pondering ways to make it stronger.

I could take an oral maoi with it - would i need to take maoi 45 minutes before dosing the 4aco?? (as i would have to do with a pharmahuasca experience)

Ive also considered Intramuscular injection - would this be stronger than swallowed orally?

And then after that there's IV 4aco. Plus a maoi.
 
Ive clearly built a big tolerance to tryptamines
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Sorry to disappoint you, but tolerance lasts 1-2 weeks at most.

200mg of 4aco fumarate isnt that strong.
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That should be the equivalent to ~28g Mushrooms. Your product is clearly degraded/bunk.
 
Other people are reporting very intense trips from 50mg. I guess a natural tolerance is possible, but 4x the amount? Have you been overdoing it or other psychedelics, done anything else in the last week or two?
 
I took 4-AcO-DMT.fumarate once a week for about 6 months straight. Zero tolerance.

Genetic abnormality on OP's part or degraded/bunk substance.

Tom
 
I have taken as much as 240mg freebase (which ive read is about 1.5* as strong as the salt/fumarate form so I guess equates to 300mg+ of the fumarate). I gave others 40mg doses of the same product on the same evening

I have also measured doses of 200mg fumarate for myself and given others 40-90mg doses and observed the effects over a number of occasions.

I seem to have a naturally high tryptamine tolerance. DMT i find hard to 'get working'. Although 5meodmt at doses of 15mg is overwhelmingly intense (so not all tryptamines are light).

Ive definitely not been using psychedelics every week and have had periods of a month away from them. MDMA has been involved in perhaps 75% of my weekends. I see 4aco as an alternative on a night out to MDMA - i can still have fun on it. The 2C family and Nbome familly i find it hard to socialise on. And LSD often doesnt work at all.

Anyway ...

I could take an oral maoi with it - would i need to take maoi 45 minutes before dosing the 4aco?? (as i would have to do with a pharmahuasca experience)

Ive also considered Intramuscular injection - would this be stronger than swallowed orally?

And then after that there's IV 4aco. Plus a maoi.

Cheers guys
 
MDMA counts, there's some cross tolerance, if you're doing MDMA every week that's the reason, you need some serotonin to trip. Have a few weeks away from all phenethylamines or tryptamines & then you'll trip harder, mdma will seem better too.
 
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A number of factors in play here. A: tolerance. B: over use of various serotonin releasing agents or selective serotonin releasing agents (Nbome's) resulting in Tolerance. C: Possible mild degradation of product. Fuck an MAOI off. Just combine a dissociative and your 4 aco dmt. The OEV's will blow your mind. Just do some research. Dose low start slow with the combo's. Less dangerous with a dissociative vs MAOI. IMI injection of both dissociative and tryptamine subtype will blow your mind but be careful with dose.

No way I'd advise 200 mg 4 aco dmt combined with say 80 mg MXE or 100 mg K. I'd start at 20-30 mg 4 aco dmt and a similar amount of dissociative drug. Say 40-50 mg MXE to 20 mg 4 aco dmt. I'd also take a couple weeks break to lower my tolerance. Also have some kind of anti-anxiety med on hand if shit gets to crazy and a sober sitter who knows whats what. Be safe and enjoy. :) Try 4 aco dpt or dipt/mipt/met/det etc. All are similar but different.
 
5 meo subtype tryptamines seem to have more adverse effects vs 4 aco/ho subtypes IME at any rate. The difference between enjoyable dose of 5 say meo mipt and a train-wreck can be just a few mg's more. So 8 mg was awesome but 12 mg's feel more than a tad sketchy. The 5 meo tryptamines are IME a bit nasty, 5 meo malt, 5 meo dalt, 5 meo dmt all nasty. 5 meo dipt and 5 meo mipt are ok but just a few extra mg's can be the difference between fun and fuck up.
 
I would obviously start with low dosages if injecting

Im intrigued by the idea of adding a dissociative into the mix but am not a massive fan of them (although I gel much better with MXE than K)

What would be the problem of mixing an oral MAOI with 4acodmt - ive ordered a pharmaceutical maoi called moclobemide [brand name "Aurorix" (reccommended by someone on here). Apparently it's a third generation Maoi with little dietary interactions [see wikipedia "No significant rise in blood pressure occurs when moclobemide is combined with amines such as tyraminecontaining foods or pressor amine drugs, unlike the older non-selective irreversible MAOIs which cause a severe rise in blood pressure with such combination"] (and allegedly no purging). It's not going to cause an 'adrenal surge' because im only taking it with a tryptamine. Also, according to Wikipedia - "Unlike the irreversible MAOIs there is no evidence of liver toxicity with moclobemide". To be honest tho, I dont really know what the fuck im doing and am asking for sensible help!?


Basically what are the dangers of a pharmaceutical maoi and 4aco?
 
What are the dangers of any MAOI. DO some research into pharmaceuticals and there properties. Moclobemide is a reversible MAOI but still... Now what your taking, possible contra indications, adverse effects. Wiki is just a starting point. Try having a look at the pamphlet provided in the meds. It's a RIMA (reversible inhibitor of Mono amine) does not mean it's automatically safe. Far from it. Read up MIMS or another source vs Wiki. It will increase the effects but... It works by preventing the breakdown of neurotransmitters. As your reading Wiki...

"The most significant risk associated with the use of MAOIs is the potential for interactions with over-the-counter and prescription medicines, illicit drugs or medications, and some supplements (e.g., St. John's Wort, tryptophan)" here is the other bit "MAOIs should not be combined with other psychoactive substances (antidepressants, painkillers, stimulants, both legal and illegal etc.) except under expert care. Certain combinations can cause lethal reactions, common examples including SSRIs, tricyclics, MDMA, meperidine,[30] tramadol, and dextromethorphan.[citation needed] Agents with actions on epinephrine, norepinephrine, or dopamine must be administered at much lower doses due to potentiation and prolonged effect."

Pretty simple. Contra indications are things like taking an SSRI and taking a MAOI. Adverse reaction would be serotonin syndrome for example from taking an MAOI and a serotonin releasing agent. Dissociatives and psychedelics are less risky IME than psychedelics and MAOI's. Take MXE and 4 aco DMT and tell me if your not blown out the water. Have a benzo or similar on hand (lower heart rate, vasoconstriction, and BP by relaxing the smooth cardiac muscles and vascular walls). Good luck with whatever you try and just dose low and go slow.

Dissociatives gel with psychedelics much better than MAOI's in my opinion/experience.
 
200 mg 4-aco-dmt is ridiculous... I have railed 60 mg with a tolerance, but 200 mg oral or railed is outrageous. 20 mg after a tolerance break with MAOI left me barely remembering the experience, which was pretty positive besides not really recollecting it.

Do not IV this stuff in case it is not pure at all... 4-aco-dmt IV is intense enough, but with impurities in it that can hurt you it is just asking for trouble.
 
lovepsychadelics said:
5 meo subtype tryptamines seem to have more adverse effects vs 4 aco/ho subtypes IME at any rate. The difference between enjoyable dose of 5 say meo mipt and a train-wreck can be just a few mg's more. So 8 mg was awesome but 12 mg's feel more than a tad sketchy. The 5 meo tryptamines are IME a bit nasty, 5 meo malt, 5 meo dalt, 5 meo dmt all nasty. 5 meo dipt and 5 meo mipt are ok but just a few extra mg's can be the difference between fun and fuck up.
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I like 5-meo-dalt at 20mg oral, or 10mg smoked, more than that messes it up. I'd agree there's not much difference between fun & fuck up, but I'd have to do 40mg oral to start feeling bad.

Mushrooms are always gentle, which this is supposed to be a little similar too, but they definitely have cross tolerance with MDMA.
 
OP; I just read the bit about MDMA on 75% of your weekends, so that's 15/20 times and add in the 8 times for 4-AcO-DMT. That is a fair bit. What about a tolerance break for a while and then the drugs will always be there when you come back to them.

When you started with 4-AcO-DMT, how much did you need, or was it always like this with this compound?

Tom
 
DrGreenthumb said:
I like 5-meo-dalt at 20mg oral, or 10mg smoked, more than that messes it up. I'd agree there's not much difference between fun & fuck up, but I'd have to do 40mg oral to start feeling bad.

Mushrooms are always gentle, which this is supposed to be a little similar too, but they definitely have cross tolerance with MDMA.
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Well the 5 meo mipt was not taken via oral administration, it was administered via insufflation. Mushrooms are always a winner. That and what Thomas Davie said.
 
ros1816 said:
Ive definitely not been using psychedelics every week and have had periods of a month away from them. MDMA has been involved in perhaps 75% of my weekends. I see 4aco as an alternative on a night out to MDMA
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MDMA downregulates 5-ht2a receptors, which is the primary target of the classic psychedelics. This would be one explanation for your tolerance.
 
I would rather take a nootropic like phenylpiracetam with it than an MAOI. That would definitely increase the strength for you. But you definitely should look into getting better 4ACO because 200 mg is a hysterical dose even for someone with a natural tolerance, that shouldn't be happening. maybe try washing it and see if and how many impurities wash off..
 
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