You are just asking for serotonin syndrome mixing zoloft and benzedrex
I'm thinking that this particular risk is actually relatively minor. SAR suggests p-hex to function like meth, albeit with drastically reduced binding affinity and efficacy, and with prominent adrenergic effects. The serotonin syndrome risk conferred by combining SSRIs with meth is actually pretty low (but non-zero, and somewhat greater than amp + SSRIs).
...
As a reminder for everyone:
beginning with 500 mg (2 cottons) is recklessly dangerous, a lengthy and unpleasant experience at
best, but possibly physically dangerous. Also, very few people have fun on that dose. Hell, I'm not sure if it's even safe to "work up" to 500 mg.
I mean, this compound has induced severe migraines, vasoconstriction and extremely high pluse and BP warranting medical attention at such doses, and even below. And depending on what noname1's dosage was, stroke-risk could be significant. One can compare with amphetamine and methamphetamine, where you have a wide enough therapeutic index to make acute overdose leading to fatality directly quite rare (with an estimated LD50 of 300-500 mg via IV, with experienced users accruing tolerance to those effects potentially fatal).
To compare, highly experienced stimulant users often have quite alarming physical symptoms in response to 2-4x a 'moderate' dose of p-hex (let's call 125 mg and under at the higher end of that level).
Please be careful, guise.
while I'm not 100% sure that propylhexedrine acts on serotonin I'm pretty confident
Why do you expect it to?
ebola