TheManFromRlyeh
Greenlighter
- Joined
- Oct 7, 2017
- Messages
- 15
I do not believe it does. I take mirtazapine and have no interactions. A friend of mine is on Prozac and he hasn't run into any problems either. We are both daily kratom users. This is just a guess, but if anything, I think kratom may lesser the efficacy of antidepressants. Kratom tends to come with a "rebound" depression, so to speak, just as other opioids do.
As far as adderall/amps with kratom, as was mentioned... I find they do not mix well together, at all. Increased anxiety being the #1 problem. Just my experience, though.
Good to know.
Here's some word of mouth I've read from other BLers over the years. Again, I have no expertise in chemistry or pharmacology, I only mean to pass this on in hopes somebody will refute or explain it further:
From one user in 2011: "Some alkaloids of kratom do affect certain monamines such as serotonin, dopamine, epinephrine, etc. It's not so much a SSRI as a non-selective reversible MAOI similar to how specific kavalactone in kava is a non-selective reversible MAO-B I."
And, as a reply to the above comment in the same thread from another user:
"Kratom does have some monoaminergic amines but I don't think it has any MAO compounds (or SSRI)."
EDIT: My god, I didn't see the OP was in 2013. Sorry if I've contributed to reviving a dead thread.