I must admit I'm deeply sceptical of anybody selling two seperate products whilst also saying they need to be taken together to be worthwhile. Seems a very odd decision. Perhaps a step-up (of sorts) from branded mixtures where you have no idea of content though. Albeit rather smacking of profiteering.
Any more specfics on effects? Sounds like mostly a straight(ish) stim kinda jobby from what you said. Also, I do believe you know a thing or two about chemistry stuffs so can you shed any more light on the suggestion that one of these compounds probably isn't active orally? Is the combo advice cos one activates t'other, perhaps?
Ok, the last 5 paragraphs contain lots of science stuff that defends the possibility that the combo works like dmt. Quite possibly of no interest to anyone but I enjoy writing this stuff anyway and if you're interested or better still want to expand on it, correct errors etc.. then that's great for me as I just love learning new stuff.
Shambles your logic is sound and I feel the sense that I have been bamboozled - along with a funny feeling that I may not be receiving much in the way of further free samples. Not that I want any if I'm being duped anyway. I'm bluelight til the end and thats all there is too it. Not in the foot ball supporter kinda way, though thats sort of starting to kick in anyway as I get to know people better. Thats a shit analogy but most of you guy's that know me know that me heads sort of screwed on backwards so can probably read between the lines. Friends, loyalty, unconscious bias even when attempting to be fair. Where was I, yeah I feel that bluelight and the whole harm reduction imperative is really important. I joined during the mxe ban and so much of what I and others wrote was about the dangers of mixing mxe and alcohol. Unfortunately the problem with alcohol is that it makes you forget what you know - however, I still like to think we saved a few lives.
Back to topic, while it does sound a little sceptical, there are a few notable combo's that spring to mind. Anyone ever tried mixing ambien and dxm? Even smallish doses of each are dicey as fuck. In fact I strongly recommend no one ever try this without a sitter. And that includes me. Ofcourse ambien gets a little hazy, but dxm isn't like that. I got the hang if it pretty quick and used to drop about 3 5mg zolpidems during a session, accompanied by moderate doses of dxm, and a nice methylone mephedrone combo. Need to go rewatch a bloodied marquez KO the Pacman now I think. I'll try and think of some more extreme synergy examples though.
Science shit starts here on. I guess I wrote this thing backwards - like what I was saying about my head I guess. Strange.
Yeah what I wrote early on about the analagy with dmt is basically one activating the other / needing to work. The actual mechanism for dmt working orally only in the presence of an MAOI is that the liver breaks down dmt so effectively that there is no dmt to enter the blood stream (this is the gist off the top of my head - certain particulars I'm not aware of but they're irrelevant to the bigger picture ie getting high off dmt ). The reason it works by inhalation is that the dmt gets absorbed along with oxygen into your blood stream which travels straight to your brain getting you high. The reason the old business mans trip last for such a short time is that the blood flowing away from the brain soon reaches the liver where it is broken down just like the stuff you ate on its own that didn't work.
So if this stuff works like dmt taken orally along with an MAOI its not that the maoi activates the dmt exactly, it actually does the opposite, it binds to whatever enzyme in your liver breaks down dmt and stops the enzyme from working properly. Maoi stands for mono amine oxidase inhibitor. Dmt is a mono amine, the liver enzyme that stops you getting high works by a process called oxidation, and the inhibitor is whatever you took eg.harmaline. ( may not be an example, like I said, off the top of my head: vader, sekio or any of the top guys could certainly expand this out but this isn't AD so I'm not gonna get into details any more than I have done ).
Anyway, the reason I did that little break down is that if this 50 50 combo thing works like that, then one of the two needs to play the role of the drug while the other needs to play the role of the enzyme duffer-upper ie the maoi type thing, that settles in your liver and stops it from breaking down the drug.
Now I intend to edit this post quite a bit if I can to try and get to the bottom if this. However, I'll freely admit that I dont know what the structure of a standard maoi looks like, though I can get to work on it. Incidently, as I'm sure most have already thought yourselfs, if this works this way then whichever one is the drug compound ought to work when smoked.
Anyway I thought I'd do that little break down of the dmt since I know, speaking to shambles, that you know a lot more about this stuff than sometimes I think you realise yourself. I see you writing things about tramadol and it being a prodrug so why shoot it up before so i know you know the biology stuff pretty good. So the dmt case is sort of like the opposite of tramadol. Tramadol is pretty shit as far as your brain is concerned, fortunately for us, god inserted something called a CYP2D6 enzyme that sees useless tramadol and duffs it up into o-desmethyl tramadol which gets us high. Unfortunately, in the case of God's drug, dmt, the liver recognises a divine compound and grinds it down into erm something sekio would know that is no good for the likes of those wishing to get high.