Established drug designer? did you go to study under a hillbilly for that?
Or do you do it all by magic? Sorry but make claims like that and you, given your prior activity have to be called out on that.
I for one, reckon you are talking shite. And established drug designer? go on? for who? because I think you are lying.
'established drug designer' doesn't mean some idiot drawing random rubbish and giving it airy fairy names, and in plenty of cases ripping off the work of Sasha Shulgin (for fucks sake! Shulgin! you are one tasteless piece of odious garbage to do that!) and giving it a new name what with your special magic powers and that.
It means someone who goes to work, studies molecules and how they may interact with clinical targets, much of the time running screenings of a great many permutations of molecules, and thousands of tiny chemical variations on such a base molecule possible drug candidate for some purpose, and then doing so for the next molecule in a huge set, along with all the 'replace this hydrogen with fluorine, change a chalcogen or halogen here, lengthen or shorten THIS alkyl group, change an ester for an ether for a thioether for a......'
And using molecular modelling software, using it to pick your candidates based on steric, van der waals, salt-bridge, halogen bonding,hydrogen bonding etc. interactions and how docking a molecule with the protein target may alter the 3D conformation of the protein, giving the drug-protein complex a whole new lot of studies needing to be calculated in energy-minimized conformation.
And of course there are the 'orbitals are for mathematicians, chemistry is for those who love to COOK!' actual real chemists. Those who are smart, intelligent, but don't work for big pharma. You are neither. You. Are. Garbage. And a liar.