Do you mean by shooting into the groin, injection into the femoral vein? Please dont do this, this is a very dangerous practice! I have personaly seen a a picture of someone dying this way (he bleeded to death). I have also spoken to folks who lost or almost lost limbs because of infections or collapsed veins in ther groin region. I was desperate for the needle for years and i have shot up almost everywhere in my body, but i was always too scarred of using the deep veins of my body. If you ever had an abcess or missed shot, you really dont want such cenario happening deep down in your body. You should really consider using your veins in your forearm. If your veins aren't visible, look on a vein map and try to find a vein with hit and luck. This probably doesnt qualify as harm reduction but its still safer in my opinion!