cannibalsnail
Bluelighter
- Joined
- Sep 18, 2011
- Messages
- 320
Is it orally active?
N&PD Moderators: Skorpio | thegreenhand
I'm sorry but your pharmacological understanding is woefully lacking. MDMA exerts the majority of its effects by releasing/preventing the reuptake of Serotonin, Dopamine and Norepinephrine. Its less pronounced effect is to agonise 5HT1-x receptors. It also has non-relevant activity at several other receptor types.
5-HT receptors are not implicated in hallucination. D2/anticholinergic system are the relevant ones here.
Wanted to add some data:
knowing what 5ht1a agonism feels like for the most part(much experience with dpt and lsd and along with 5-meo-dmt I'm almost certain I know what 5ht-1a in general feels like, to simplify how it feels a lot while still giving an idea: meditative/timeless feeling, interesting kind of relaxed euphoria with paradoxical rough edges to it, contentedness)
lol thanks for the caution man