DevilSmile
Greenlighter
- Joined
- Oct 27, 2011
- Messages
- 33
All I want to know
This chart indicates that chlorpromazine (CPZ) will reduce the effects of LSD, and CPZ is a good indicator of how other phenothiazines might interact with LSD. However, I have heard that this effect does not extend to the atypical antipsychotics such a quetiapine (seroquel) -- which would most likely be designated as <--> if it were included in the chart above.
As an aside, I found it interesting that methamphetamine (MA) reduces the effects of LSD while amphetamine and methylphenidate increase the effects. This must be due to MA's significant 5-HT releasing effects, because 5-HT is a better agonist at 5-HT2A than LSD is.