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    Non prescription anti-anxiety drugs? 
    #1
    Anyone know of non-prescription/OTC anti-anxiety drugs? Not for recreational use.
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    #2
    Depending on your anxiety level, St. John's Wart or melatonin are probably the most effective. But that are nothing compared to a benzo. The only OTC drug comparable to a benzo for anxiety is alcohol.
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    #3
    Bluelighter laCster's Avatar
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    l-tyrosine and sublingual GABA supps work well.

    kava kava and valerian root do a pretty good job at suppressing my anxiety, and kratom is the shit, but it isnt OTC but it is legal
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    #4
    Quote Originally Posted by SPC123 View Post
    Depending on your anxiety level, St. John's Wart or melatonin are probably the most effective. But that are nothing compared to a benzo. The only OTC drug comparable to a benzo for anxiety is alcohol.
    Melatonin!? That's a natural sleep aid supplement. It's used mostly for people with jet lag, and have problems sleeping. I fail to see how that might help anxiety at all, besides making the user sleepy.

    I think the best drug for anxiety, is fresh food and eating healthy. Simple as that. Also, plenty of exercise. Don't be so quick to resort to substances.
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    Bluelighter the_ketaman's Avatar
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    I tried phenibut a few years ago and remember it helping considerably but I only tried it once so it may have been placebo, it was a long time ago. I dont know much about phenibut but I know it works on the GABA receptors and it has a pretty bad withdrawal if overused so if you go this method be very careful. Im considering getting some as it is legal.
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    #6
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    L-Theanine is the best OTC anti-anxiety drug that I have taken.
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    #7
    Quote Originally Posted by J.Wallace View Post
    Melatonin!? That's a natural sleep aid supplement. It's used mostly for people with jet lag, and have problems sleeping. I fail to see how that might help anxiety at all, besides making the user sleepy.

    I think the best drug for anxiety, is fresh food and eating healthy. Simple as that. Also, plenty of exercise. Don't be so quick to resort to substances.
    Yes, melatonin. Studies show it has anxiolytic properties. Also, fresh food and healthy eating might help with stress and anxiety that is not clinically disordered, but it won't be of much help to someone with an anxiety disorder. I should know; I used to work out 6 days per week and eat very healthful foods, keeping track of every calorie, and its source. This made me feel better overall, but did nothing to remedy my anxiety, nevermind mitigating panic attacks.
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    #8
    L-tryptophan, L-tyrosine, Taurine, Valerian root, Magnesium, Kava Kava, Ginko Biloba, Phenibut, Melatonin

    Sometimes I feel like tackling anxiety at different angles other than benzos or beta-blockers is the best bet.
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    #9
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    GABA supplements work amazing. Look into them.
    The problem that I found was when I was using GABA daily and then I used MDMA - the MDMA did not work nearly as much.
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    #10
    Do you need a prescription for beta-blockers?
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    #11
    And what about phenibut? Can you pick those up at a local retail store?
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    #12
    Beta blockers are prescription only. They are an early blood pressure and cardiac arrhythmia medication. Note that beta blockers will alleviate the physical symptoms of anxiety (sweating, trembling, stuttering) but won't reduce mental anxiety. In other words you'll still be anxious, you just won't look like you are. The easing of physical symptoms can help you relax though, especially in the case of social anxiety and/or performance phobia.
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    #13
    Quote Originally Posted by wiggi View Post
    L-Theanine is the best OTC anti-anxiety drug that I have taken.
    I agree..when I was on probation i picked up a bottle cheap...and it helped me not want to violate my terms of probation!

    Local Stores sale concauctions called Nerve Tonic.. they make me feel less anxious.
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    #14
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    The good stuff you have to get from your doctor. Sad but true.
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    #15
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    There is some evidence for hydroxyzine (1st gen antihistamine but with low anticholinergic activity and some serotonin/alpha-adrenergic antagonist action which may be resplosible for it's anxiolysis) but this is not OTC everywhere. I have a paper but I can't access it here - it shows promise in generalised anxiety disorder, but it doesn't work for everyone.

    Beta blockers are indeed prescription only - they work on the physical symptoms of anxiety (primarily racing heart but also tremor and nausea) and some people find them very effective, leading to a calmed mind with improved physical symptoms - others less so. Pregabalin (Lyrica) and gabapentin can sometimes work too, but again prescription.

    Some people find Valerian root to have a calming effect but I don't have any evidence or experience to support this..

    Have you tried breathing exercises and therapy such as CBT?
    Last edited by effie; 13-04-2012 at 02:30.
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    #16
    Quote Originally Posted by J.Wallace View Post
    I think the best drug for anxiety, is fresh food and eating healthy. Simple as that. Also, plenty of exercise. Don't be so quick to resort to substances.
    Im 32 years of age, i have always had an extremely well balanced healthy diet and i ride a pushbike a minimum of over 50 miles (80 kilometres) per week yet i still suffer from crippling/life controlling Anxiety and have done for many years.

    It may work for some but not for me :/
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    #17
    Bluelighter weekend addiction's Avatar
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    Kava kava. Or alcohol.
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    #18
    Quote Originally Posted by effie View Post
    There is some evidence for hydroxyzine (1st gen antihistamine but with low anticholinergic activity and some serotonin/alpha-adrenergic antagonist action which may be resplosible for it's anxiolysis) but this is not OTC everywhere. I have a paper but I can't access it here - it shows promise in generalised anxiety disorder, but it doesn't work for everyone.
    Damn right it doesn't work for everyone!

    I tried this on recommendation from a pharmacist in South-East Asia (Brand name Atarax) and i found this to be an horrific experience! I wont go into detail as this may unfairly influence the reader but i followed the instructions and eer'd with the side of caution (which is something i rarely do when it comes to illicit substances)

    The next 48 hours were the worst of my life without going into detail, this aside taking more than the recommended dose of this Anti-Histamine is a very bad idea

    I would not wish it on my worst enemy.

    IME it most definately does not possess any Anxiolytic properties, infact on the contrary ive never felt so anxious in all my life, aswell as sweaty, restless, nauseas and just generally awful.

    On top of this i was stuck on a 747 waiting on the runway to take off!

    A nightmare experience of epic proportions... especially for someone like me who originally wanted the meds for flight anxiety and now had all these symptoms brought on by the Hydroxyzine aswell as my usual extreme flight anxiety symptoms add to that the fact i had a 12 hour non-stop flight ahead off me.

    So not wanting to dismiss this 'wonderdrug' (Hydroxymine) ive tried using it on different occassions using different doses in different settings and my opinion has not changed at all.

    Maybe im one of the unlucky few who it doesnt seem to work on, yet all the other 1st Generation Anti-Histamines ive tried (and use) work just perfect.
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    #19
    Bluelighter ErgicMergic's Avatar
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    -600mg Chelated Magnesium Glycinate (try this first)
    -400-600mg L-Theanine
    -Kava-Kava tincture in glass bottles, 40-80 drops
    -Beta Blockers for the physical symptoms of anxiety, these are so effective and so easy to get from doctors

    Also,
    -A normal, restorative sleep every night
    -Good meals every 4 hours (complex carbs, protein, good fats)
    -No caffeine, stimulants, or sugar
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    #20
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    Bach's Rescue Remedy works extremely well also. It is a tincture you place under your tongue. Relora is pretty good too
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    #21
    St. John's Wart has been reported to do quite a nice job with depression and anxiety, exhibit effects similar to rx anti-depressants. Valerian Root is very good IME with anxiety and sleep trouble. It is GABAergic, and really shouldn't be underestimated. Magnesium helps with some in a calming. I believe Kava Kava has some anxiolytic properties, but can be stimulating, too, and has varied effect. Other serotonergic supplements like pre-cursors are reported to help some.
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    #22
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    Quote Originally Posted by J.Wallace View Post
    I think the best drug for anxiety, is fresh food and eating healthy. Simple as that. Also, plenty of exercise. Don't be so quick to resort to substances.
    I also have to take issue with this kind of generalised statement and not for the first time this evening, yet again we have people not thinking very carefully about what they post regarding this MEDICAL condition and how it may make thee OP feel.

    I absolutely agree that for everybody including those with mental health issues a healthy diet and a moderate bit of exercise can do wonders for your over all health. I'm well aware that exercise release chemicals into the brain which may well help with anxiety and depression and make you feel better in general, mental health issue or not.

    However for many people their condition may be to acute to be able to effectively make those changes and those changes alone are very unlikely to resolve the underlying problems that led to the mental health issue in the first place, the issue may be much more complex, at this stage the OP seems to be self diagnosing anxiety as well as wanting to self medicate. I'm not saying that's wrong but they are the facts we are working with.

    This is just another example of blaming the patient for their condition, in this case what is being said is that "you eat a shitty diet and don't take enough exercise" so it's your fault you have anxiety.....Ronald McDonald always seems pretty chirpy to me.

    For all we know know the OP east a fantastic diet and runs a marathon every month.

    I'm going to stop now as my blood is likely to approach boiling point
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    #23
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    it's not OTC, but any doctor will prescribe it as it is not addictive or dangerous in any way... hydroxyzine (Atarax) wworks for mild anxxiety dissorders
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    #24
    atm, you'd be hard pressed to find someone who eats healthy and runs a marathon every month who haa sever anxiety or depression... that doesn't mean those behaviors will cure the condition though. People constantly confuse correlation with causation... people who are anxious and depressed are less likely to be concerned with their diet and exercise if they're consumed with feelings of dread or hopelessness!

    It would certainly be beneficial for anyone to try to put more emphasis on taking care of themselves but this alone is unlikely to 'cure' someone who meets the clinical criteria for any mental health condition.

    With that said, I also think many (especially around here) over-rely on substances to treat many conditions, especial mental health problems. Most anxiolytics quickly become counterproductive when used regularly and are more appropriate in the short-term while the cause of the malady is explored with qualified professionals and healthy, sustainable means of addressing the problem and finding lasting resolution (or at minimum, avenues for amelioration) are sought out.
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    #25
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    ^^^

    I understand what you are saying, however I still challenge the statement "I think the best drug for anxiety, is fresh food and eating healthy. Simple as that. Also, plenty of exercise. Don't be so quick to resort to substances."

    I admit to using an extreme to try and make the point, apathy and a lack of interest in exercise or socialising are both symptoms of anxiety and depression, I do not believe it is the other way around.

    I did make it clear that it is important, as it is for all, depressed or not eat a healthy diet and ensure they use moderate exercise although this can be very hard when you find just eating out of bed in the morning a significant issue.

    My concern is that a view is not presented that suggests that those that do not exercise and eat the greatest diet are to blame for their depression, that may not have been the OPs intention but I think it is very important not to lay the blame for such a condition at the sufferers door, it can only be counter productive in such a situation, given the almost inevitable guilt and and low esteem they will already be suffering.

    All of that said I do not believe that drugs alone can "fix" depression or anxiety issues in the vast majority of cases, I would say all but I'm in no position to make such a statement. I believe that drugs can offer some stability and breathing space for treatments such a CBT or whatever your psychiatrist deems suitable for your individual needs.

    For me a combination of ADs (in my case Vanlafaxine) and CBT along with some moderate exercise, I walk the dog twice a day, I've stopped drinking alcohol and am on my way to stopping benzos has made a massive difference to my outlook.

    I stand my statement, if you believe you are suffering from anxiety or depression get yourself to a doctor ASAP, do not wait whilst you join the lpcal gym, which you probably won't go to or change to a raw vegetable diet that your going to give up in a week....again extremes, but having had more than one condition where the where both the medical profession and others seem to want to blame the patient I have strong feeling on the subject so my apologies if this has come over a little harshly, its close to my heart.
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