I want to get information on L-Tyrosine.
Of course I found information but not exactly what I wanted...
I know how it is said to work, e.g. l-tyrosin-->l-dopa->dopamin. But in can also result in other products (L-Triiodthyronin or L-Thyroxin or Tyramin).
But this is not so interessting for me. I wanted to know what it does to the persons who ingested it. I wanted to get some experience reports because big parts of the information I found were contradictory. And I don't trust the information found on the websites of amino acid vendors...
Sometimes I read that L-tyrosin had a calming effect. But others wrote that it gave them new power.
I read that it really helped some people during opiate withdrawal. Some people claimed that it helped them when they had absolutely no power during withdrawal.
Other wrote how splendidly it helped after acute withdrawal when PAWS was really dreadful.
So I tried to find some more experience reports. Especially because I still did not know it it acts more calming or more powerful.
Usual dosage was 300-1000mg daily for most people who experimented with tyrosine.
I cannot really believe that it is possible to feel an effect from that dosage. I don't know the persons who tried that but it seems for me, that some of those people felt something what actually wasn't there. It really looks like lots of placebo effects.
There are some foods that are high in tyrosine, e.g. Gruyere cheese. 100g shall contain around 1776mg tyrosine. That is really a lot, because usual tyrosine supplement capsules contain 500-1000mg. If some people felt an effect from only 1-2 capsules, I should also felt an effect after I ate more than 100g Gruyere cheese. But I never felt anything from eating old, ripe cheese.
And then L-tyrosine is also sold as bodybuilding supplement. Bodybuilders sometimes take a lot larger doses - up to 3-5 gram a day. I searched bodybuilding forums where they discussed tyrosine as supplement. But noone of those bodybuilders ever reported any mental effects.
So does tyrosine really work? - Yes, probably it "works" but is it also possible to feel an effect after ingestion of 1 or 2 capsules?
For me l-tyrosine would be interessting as supplement for opiate withdrawal. If it would calm me down a little bit when I am all churned up inside, that would be great. If it would help when I feel totally powerless and have absolutely no motivation to get up from my couch, that would be great, too.
And maybe it could really increase my dopamine levels in the brain during withdrawal. Perhaps it could help during PAWS time with depression, anxiety, cravings, ...
Who took this stuff? How much did you take? And what did you feel? Nothing? Or did you feel an effect that was for sure more than placebo effect?
And how should tyrosine be ingested?
When it is converted to L-Dopa, L-Dopa cannot cross the blood brain barrier. This is why persons who suffer from Parkinson's disease don't get only L-Dopa. They also get a decarboxylase inhibitor. This is responsible for that L-Dopa does not gets converted to dopamine in the body. It first crosses the blood brain border and then gets converted to dopamine.
But what is with tyrosine? When it gets converted to L-Dopa, I probably have the same problem. L-Dopa must not get converted before it crosses the blood brain barrier...
Some vendors sell L-tyrosine combined with vitamin b6. I know that vitamin b6 and ascorbic acid are said to be cofactors for the conversion.
Vitamin b6 is probably needed for conversion from tyrosin to l-dopa, I think. But I don't know what exactly is the role of vitamin c.
I also don't know if the combination with vitamin b6 is so desirable.
In case of 5-HTP (which is often combined with vitamin b6 by the vendors) it is absolutely not desirable because I don't want the 5-HTP to be converted to serotonin in the body. This shall only happen in the brain.
So what with tyrosine and vitamine b6 and/or vitamin c?
Of course I found information but not exactly what I wanted...
I know how it is said to work, e.g. l-tyrosin-->l-dopa->dopamin. But in can also result in other products (L-Triiodthyronin or L-Thyroxin or Tyramin).
But this is not so interessting for me. I wanted to know what it does to the persons who ingested it. I wanted to get some experience reports because big parts of the information I found were contradictory. And I don't trust the information found on the websites of amino acid vendors...
Sometimes I read that L-tyrosin had a calming effect. But others wrote that it gave them new power.
I read that it really helped some people during opiate withdrawal. Some people claimed that it helped them when they had absolutely no power during withdrawal.
Other wrote how splendidly it helped after acute withdrawal when PAWS was really dreadful.
So I tried to find some more experience reports. Especially because I still did not know it it acts more calming or more powerful.
Usual dosage was 300-1000mg daily for most people who experimented with tyrosine.
I cannot really believe that it is possible to feel an effect from that dosage. I don't know the persons who tried that but it seems for me, that some of those people felt something what actually wasn't there. It really looks like lots of placebo effects.
There are some foods that are high in tyrosine, e.g. Gruyere cheese. 100g shall contain around 1776mg tyrosine. That is really a lot, because usual tyrosine supplement capsules contain 500-1000mg. If some people felt an effect from only 1-2 capsules, I should also felt an effect after I ate more than 100g Gruyere cheese. But I never felt anything from eating old, ripe cheese.
And then L-tyrosine is also sold as bodybuilding supplement. Bodybuilders sometimes take a lot larger doses - up to 3-5 gram a day. I searched bodybuilding forums where they discussed tyrosine as supplement. But noone of those bodybuilders ever reported any mental effects.
So does tyrosine really work? - Yes, probably it "works" but is it also possible to feel an effect after ingestion of 1 or 2 capsules?
For me l-tyrosine would be interessting as supplement for opiate withdrawal. If it would calm me down a little bit when I am all churned up inside, that would be great. If it would help when I feel totally powerless and have absolutely no motivation to get up from my couch, that would be great, too.
And maybe it could really increase my dopamine levels in the brain during withdrawal. Perhaps it could help during PAWS time with depression, anxiety, cravings, ...
Who took this stuff? How much did you take? And what did you feel? Nothing? Or did you feel an effect that was for sure more than placebo effect?
And how should tyrosine be ingested?
When it is converted to L-Dopa, L-Dopa cannot cross the blood brain barrier. This is why persons who suffer from Parkinson's disease don't get only L-Dopa. They also get a decarboxylase inhibitor. This is responsible for that L-Dopa does not gets converted to dopamine in the body. It first crosses the blood brain border and then gets converted to dopamine.
But what is with tyrosine? When it gets converted to L-Dopa, I probably have the same problem. L-Dopa must not get converted before it crosses the blood brain barrier...
Some vendors sell L-tyrosine combined with vitamin b6. I know that vitamin b6 and ascorbic acid are said to be cofactors for the conversion.
Vitamin b6 is probably needed for conversion from tyrosin to l-dopa, I think. But I don't know what exactly is the role of vitamin c.
I also don't know if the combination with vitamin b6 is so desirable.
In case of 5-HTP (which is often combined with vitamin b6 by the vendors) it is absolutely not desirable because I don't want the 5-HTP to be converted to serotonin in the body. This shall only happen in the brain.
So what with tyrosine and vitamine b6 and/or vitamin c?
. After maybe a week or being on 2mg's of risperidone in the morning and 300mg's of seroquel at night (i think that was the cocktail i was on) i could finally sit still for 5 minutes.
).