Cloudy
Bluelight Crew
- Joined
- Aug 9, 2005
- Messages
- 5,659
Yeah rectal administration can have as fast if not faster than nasal depending on the drug, of a come up time (alot faster than oral), it also avoids being metabolized through a first pass metabolism, it doesn't have to deal with stomach contents and its pH, etc. This basically means it can come up pretty fast with a decently high bioavaliability (depends on the drug to what % it may be), maintain a similar duration as if taken orally, and can limit the number of side-effects like intense nausea that oral administration can some times have. Rectal administration for the win. I love doing MDMA rectally, some opiates rectally, 4-meo-pcp rectally, etc.