Is DMT the only psychedelic that tolerance cannot develop with? From my experience 5-meo-DMT seems to have this property as well.
Does this happen with MET, DET, DPT or DiPT?
I know tolerance doesn't develop with oral DMT, would this be the same for other tryptamines + MAOI? Are there any other drugs that do not develop tolerance at all? Maybe salvia?
And lastly, how does this work? Is it dependent on the metabolism of the drug or does it have to do with 5HT-2a receptors?
I know this is more than one topic, but it seems very odd and unique to me, seems like a worthwhile discussion.