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    Chocolate: Opiate Potentiator? 
    #1
    Sorry if this has been posted before, but i did try to use the search feature and really didnt find anything.


    On an empty stomach i ate a little less than half a bar of hersheys dark chocolate. Probably took a 10mg lortab about 30 minutes later. 3 hours go by and the effect is wearing off. Then after about another hour when im sitting in traffic, BAM! The pill starts to come on again. This was 3 hours ago and im still feeling it. So 7 hours total.

    I have never experienced a pill like that come on again so strong. In fact, i have never had a second rush from an opiate before.. ever. And i am amazed it happened 4 hours after i took it.

    It took me some time to figure out what happened as i just put 2+2 together. Note: this is not placibo effect. I have never heard of or even thought of the possibility of chocolate making opiates stronger. I did do a internet search and while there are some hints that it might, there is no definite clearification on it like there is for grapefruit juice and opiates.

    I have taken grapefruit juice to potentate pain killers before but i can tell you now, dark chocolate is MUCH better at doing it. At least it was tonight. If anybody else has had an experience like this with chocolate and opiates i would like to know.
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    #2
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    Chocolate has been linked to changes of serotonin levels...It's possible that it could add to the opiate high, though I wouldn't have thought it'd be anything noticeable at all.

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    #3
    Bluelighter Znegative's Avatar
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    NO I actually immediately clicked on this link cause I know what the OP is talking about. Every morning when I take my .5 mg of suboxone, I eat a small piece of chocolate, because I swear it potentiates it (doesn't make me nod out, but it is noticeable.) It's kind of like how all the people at methadone clinics drink coffee to feel the methadone work, and i think its kind of a similar thing here. Chocolate contains caffeine and IME caffeine does affect opiate use. Speaking of which i better eat that chocolate now (if you take it rectally, you get 40% better BA by the way)
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    #4
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    I don't think chocolate contains any caffeine, unfortunately.

    Here's why

    Unless of course the brand of chocolate you're eating has caffeine added.

    The delicious Hershey's chocolate that the OP is eating doesn't contain any caffeine, so we can rule caffeine out as the cause.

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    #5
    Bluelighter Znegative's Avatar
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    I read somewhere that chocolate also weakly attaches itself to THC receptors, though you would have to eat 25 pounds of it to get a marijuana like buzz, perhaps this is the mild stimulus that the OP talks of
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    #6
    Bluelighter ErgicMergic's Avatar
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    Chocolate releases dopamine, and norepinephrine, because of the phenethylamine in it. Letting a piece of dark chocolate melt on or under your tongue (sublingual?) relaxes some people.

    Why do you think some women are addicted to chocolate? It tastes good and releases a bunch of dopamine (as much as food can, anyways).

    EDIT: edited serotonin -> norepinephrine
    Last edited by ErgicMergic; 18-12-2011 at 12:59.
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    #7
    Bluelighter Opiates4lyfe's Avatar
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    If caffeine potentiates opiates why the heck have I not felt any different when gulping down pop?
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    #8
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    I take 400mg of caffeine every morning with my oxycodone dose. It DEFINITELY helps out a lot. The I potentiate my second dose with a high fat meal I'm gonna try this chocolate thing tonight.... maybe that will be my third dose potentiator.
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    #9
    definetely not.
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    #10
    Quote Originally Posted by lowdo View Post
    I take 400mg of caffeine every morning with my oxycodone dose. It DEFINITELY helps out a lot. The I potentiate my second dose with a high fat meal I'm gonna try this chocolate thing tonight.... maybe that will be my third dose potentiator.
    Thats a lot of caffeine.


    Anyway just to be more precise. It was a little less than half a king size bar. So about a normal size bar of chocolate. I also forgot that i took a multivitamin right before as well.
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    #11
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    Chocolate contains theobromine and theophylline, if I'm not mistaken - two closely related dimethylxanthines that are metabolites of caffeine. They're all adenosinergic stimulants. There's significant levels in dark chocolate, and I'm sure they'd potentiate opiates to some extent. (Wasn't the freebase Heroin #3 mixed 50/50 with caffeine for smoking?)

    I don't think I'd go so far as to say that chocolate, or any compound therein, releases dopamine, serotonin, etc like an amphetamine. that's just plain silly. The release is porbably more from the delicious taste of the cocoa
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    #12
    Chocolate does infact contain caffeine, most dark chocolates don't but milk chocolate does, I have to avoid chocolate when my pain is causing migraines for that exact reason, caffeine makes my pain and migraines much worse.



    QUOTE=JSPete;10179536]I don't think chocolate contains any caffeine, unfortunately.

    Here's why

    Unless of course the brand of chocolate you're eating has caffeine added.



    The delicious Hershey's chocolate that the OP is eating doesn't contain any caffeine, so we can rule caffeine out as the cause.[/QUOTE]
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    #13
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    I take back everything.

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    #14
    Lol hey most people wouldn't have thought it contained caffeine but it does, hence the buzz mixed in with the natural products that boost dopamine.

    I love chocolate but I shouldn't really eat it. I am definitely going to try this out with my next dose of medication though

    That with everything else I am taking to potentiate my medication may help but I should really do it on it it's own so I can tell which product is doing the work. I sense I science project coming on hehe.
    Last edited by Doomed2pain; 17-12-2011 at 21:59. Reason: Added
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    #15
    i agree with whoever said it relases serotonin and stuff like that also ive done it a few times but i just thought it was more of a placebo effect maybe they both play a little role in making it better
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    #16
    Bluelighter Fire&Water's Avatar
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    [QUOTE=Znegative;10179523]NO I actually immediately clicked on this link cause I know what the OP is talking about. Every morning when I take my .5 mg of suboxone, I eat a small piece of chocolate, because I swear it potentiates it (doesn't make me nod out, but it is noticeable.) It's kind of like how all the people at methadone clinics drink coffee to feel the methadone work, and i think its kind of a similar thing here. Chocolate contains caffeine and IME caffeine does affect opiate use. Speaking of which i better eat that chocolate now (if you take it rectally, you get 40% better BA by the way)[/QUOT
    Last edited by Fire&Water; 13-02-2012 at 03:35.
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    #17
    Bluelighter lenses's Avatar
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    Chocolate contains barely ANY caffeine , no more than 15mgs . As for any significant alkaloids or chemicals in chocolate that would potentiate an opiate high , milk chocolate is not going to contain any appreciable amount of anything to effect you. Dark chocolate , maybe, but it would have to be a big amount. I think you're feeling a placebo my friend...

    Its like trying to get jacked up on pepsi or mountain dew. Sure it has caffeine, but not a lot. I think its funny when people say "oh man I got a lot of work to do today, I need a coke to wake me up.". Ooooh 34mgs of caffeine.

    Hah, don't mean to rant, but people still believe chocolate will keep you awake with its caffeine. No.

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    #18
    hah, people and there mind drugs
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    #19
    Bluelighter ErgicMergic's Avatar
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    Lenses, I pretty much agree. Chocolate definitely does not have enough caffeine to be stimulatory on its own. However, cocoa also contains theobromine and theophylline, which are methylxanthines like caffeine, that act as stimulants. This would have to be dark chocolate (has more cocoa), and I'm not sure how much of it, but combine that with the fact that chocolate has phenethylamine, which breaks down in to DA and NE, and you can see how chocolate can be stimulatory in some people.

    I can say phenethylamine definitely has noticeable effects when you just need that extra dopamine boost, or that extra analgesia from opiates, when I drink a couple packets of Aspartame, which contains it, with a couple cups of tea.
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    #20
    I think the reason is the fat solubility that the chocolate brings to the table.

    Essentially, the chocolate helped draw more of the opiate into your bloodstream.

    Chocolate is psychoactive, but only to a very minor degree.
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    #21
    Quote Originally Posted by lenses View Post
    Chocolate contains barely ANY caffeine , no more than 15mgs . As for any significant alkaloids or chemicals in chocolate that would potentiate an opiate high , milk chocolate is not going to contain any appreciable amount of anything to effect you. Dark chocolate , maybe, but it would have to be a big amount. I think you're feeling a placebo my friend...

    Its like trying to get jacked up on pepsi or mountain dew. Sure it has caffeine, but not a lot. I think its funny when people say "oh man I got a lot of work to do today, I need a coke to wake me up.". Ooooh 34mgs of caffeine.

    Hah, don't mean to rant, but people still believe chocolate will keep you awake with its caffeine. No.

    -lenses
    Im sorry but the fact you say people dont get jacked up on mountain dew really lowers your credibility.
    Placebo? Go back and re-read my post. You obviously did not.
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    #22
    Quote Originally Posted by ambigroove View Post
    Im sorry but the fact you say people dont get jacked up on mountain dew really lowers your credibility.
    Placebo? Go back and re-read my post. You obviously did not.

    Good flame ambi I'm gonna post a pic of ingredients tonight when I get some chocolate
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    #23
    Bluelighter
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    Hmm intresting... I have some dark chocolate 70% cocoa around but I hate the taste! ;/

    I will eat some before my next morphine dose and see if it potentiated it.
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    #24
    Dairy milk would be better for the caffeine. And tastier too
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    #25
    Bluelighter ErgicMergic's Avatar
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    Quote Originally Posted by OnCloud9 View Post
    Hmm intresting... I have some dark chocolate 70% cocoa around but I hate the taste! ;/
    mmmm dark chocolate

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