Bluelight

Thread: Ace/Ibuprofen Plugging Q.

Results 1 to 6 of 6
  1. Collapse Details
    Ace/Ibuprofen Plugging Q. 
    #1
    Bluelighter
    Join Date
    Mar 2007
    Location
    OZ land
    Posts
    1,353
    Would plugging codeine with ibuprofen (I know the bio orally is higher) be safe? I remember reading somewhere that anal absorption of ace/paracetamol is inneffective as the drug is very poorly absorbed into the anal wall.

    What about ibuprofen? I'm just feeling like changing things up a bit, and am feeling lazy (cbf the CWE! )

    Thanks.
    Reply With Quote
     

  2. Collapse Details
     
    #2
    Bluelighter 'medicine cabinet''s Avatar
    Join Date
    Jun 2006
    Location
    Baltimore
    Posts
    7,028
    For gods sake please dont do this. just take the pills orally. besides i am pretty sure codeine is a prodrug, so you would need to take it orally for your liver to metabolize it on 1st pass. So yeah, just stick to taking them orally.
    Reply With Quote
     

  3. Collapse Details
     
    #3
    Bluelighter
    Join Date
    May 2009
    Location
    Canada
    Posts
    323
    ^ This dude is right codeine is a pro drug so take it orally. Who wants tylonel up the bum anyway.
    Reply With Quote
     

  4. Collapse Details
     
    #4
    Moderator
    Neuroscience and Pharmacology Discussion
    sekio's Avatar
    Join Date
    Sep 2009
    Location
    Seat of Power, Constantinople
    Posts
    17,648
    APAP and ibuprofen diffuse quite well across the rectum, the mfg's even sell Tylenol/Panadol suppositories. Codeine rectally is a waste of time as others have pointed out, however.
    Reply With Quote
     

  5. Collapse Details
     
    #5
    Bluelighter
    Join Date
    Apr 2009
    Location
    Toxic Wasteland
    Posts
    935
    this will BURN. In fact i think its the main contributing factor to the hemmorhoid I had several months ago. DO NOT DO THIS!!! unless you want a hemorrhoid or chemical burn feeling in your anus. (this was with 100 mg ibuprofen in the form of vicoprofen).
    Reply With Quote
     

  6. Collapse Details
     
    #6
    Bluelighter
    Join Date
    Mar 2007
    Location
    OZ land
    Posts
    1,353
    Haha...all right I get your message ...oral it remains
    Reply With Quote
     

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •