I notice that most opiates are excreted renally, does this mean that there is a lot of strain put on your kidneys by using opiates?
I have two questions:
1) If a healthy person indulged in large doses of opiates each day, would this have an adverse affect on their kidneys?
2) If a person (or animal) was in pain due to kidney failure, would opiates be used to treat them for the pain, or would this cause unnecesarry strain on the kidneys? If opiates weren't used, what would be used for pain relief for someone suffering from kidney failure, if anything?