Light: 25 - 150 mg
Medium: 150 - 350 mg
Strong: 250 - 500 mg
Very Strong: 400 - 800 mg
Dangerous: 800+ mg
As far as dosing and effects go,
100mg: sleepiness, maybe some audio hallucinations. It'll be tough to stay awake.
200mg: sedation and mild delirium, mild hallucinations like bugs flying across visual field and things of the like. They'll pop up and be gone before you really catch whats going on
300mg: Same as 200mg except more intense. Definite delirium and difficulty motivating yourself to stay awake. Visuals are more present. You might see bugs crawling in your skin and be able to comprehend some things like bugs before you fall asleep. Things that are really there might have different facial expressions. Audio hallucinations. Intense drymouth and uncomfortable.
400mg: Intense delirium. Symptoms are very similar to schizophrenia. You'll see people pass by that don't exist. If you close your eyes you'll think your in a different place. Difficulty speaking and restlessness occurs. Heart rate increases and it's difficult to get comfortable. Staggering and depth perception will occur
500mg: Very intense delirium. Walking is increasingly difficult. Walls will have patterns, random things will pop up and fake people will be seen and will converse with you. Speech and motor function is extremely difficult, and not much more than mumbling will come out at most. You will think your in one place at a different time of day, then quickly flash to another place. Staying at one place at a time for roughly a minute. It becomes very uncomfortable and falling asleep will be difficult. You won't know if your awake or dreaming, and if not lying in bed "sleepwalking" may occur, but you'll be bumping into walls and cannot comprehend where your going. Drymouth seems uncurable, no matter how much water. Possible sickness
Anything over 600mg may cause blackouts and dangerous for the heart, especially without a tolerance. Although people have taken over 1g and have survived, but remember very little of their trip, and cannot recall what was reality or hallucinations.
Note: The aforementioned list are general effects. Everyone reacts differently to diphenhydramine, but after reading multiple trip reports these are the most common effects.
Effective dosages vary greatly from person to person, based on factors such as body weight, tolerance, and other unknowns. There have been people taking doses higher than 800 mg and have been fine, but once someone gets to dosages that high, it begins to put strain on his or her heart. Some may take 500mg one night and not reach the desired effects, and then on a different night take the same dose and become overwhelmed. This chemical tends to be on the darker side and extremely random and is part of the reason why its popularity is low.
Tolerance develops extremely fast for diphenhydramine and seems to disappear slowly, so it is a good idea to space out diphenhydramine trips rather than increasing one's dosage to compensate for this tolerance. Compensation can become dangerous, because it is impossible to tell at exactly what dose diphenhydramine will become dangerous to one's health.
Dimenhydrinate dosages are roughly twice those of diphenhydramine dosages, as there are 29 mg of diphenhydramine per 50 mg of dimenhydrinate.
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