Do not shoot APAP. You could use a micron filter (actually, you would have to) to filter out all the APAP and other binders and shoot the oxycodone but it wouldn't be worth it at all if you ask me. Oxycodone has a crazy high oral bio-availability anyway.
What's been said. It's extremely risky to shoot these pills and not really worth it anyway.
If you must, please follow correct (and safe) HR procedure and use a micron filter (refer to this thread/FAQ for information on how to go about doing this...again...if you absolutely must shoot it in the first place).