Deacetylation of heroin into morphine when taken orally occurs during presystemic metabolism which is completely bypassed when taken nasally. So not the same but stronger snorted than eaten. Hence why dope is often snortedWhen comparing heroin to other opioids through the oral or intranasal routes, look at the morphine conversions. Heroin when taken orally is morphine, they are equipotent because heroin is a morphine prodrug (6-MAM is not even formed through the oral route, and it's only a minor metabolite through the IV route). I think it's the same intranasally (same as oral), but I could be wrong.
Deacetylation of heroin into morphine when taken orally occurs during presystemic metabolism which is completely bypassed when taken nasally. So not the same but stronger snorted than eaten. Hence why dope is often snorted
^ha, I like that analogy - propellers. It creates an adorable image in my head of junk in little tiny biplanes in the brain
hey guys, a quick questions about post-injection site inflammation. (sorry if this isn't the right place to post this, but i figure a post in an existing thread is better than starting a new one).
anyways, almost, but not every time i shoot i get worse than usual sting and swelling around the injection site, even after registering and taking plenty of time during the injection process. i use tar heroin, about 40 units in a 27 gauge syringe. i of course make sure to aim the needle point inwards, but i wonder... does the nasty sting and swelling occur because i'm shooting AGAINST the flow of blood through the vein?
again, sorry if this isn't the appropriate place to post this, i'm just curious as to a possible solution to my post-IV difficulties as i basically use alone and don't really have anyone to compare notes with.