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Thread: Methadone and Ambien

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    Methadone and Ambien 
    #1
    Dosed Methadone for first time about 4 hours. Total dose 15mg. Can definitely feel it, but only very subtly. I take Ambien CR 12.5mg everynight (I have a high tolerance so I usually take 2-3 of them and chew them up rather than taking them whole). Question is, is it safe for me to take just 1 Ambien CR tonight after dosing the Methadone?
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    #2
    Never heard anything back so I just went ahead and took one Ambien CR 12.5mg. I'll report back in half an hour unless I have some sort of awful reaction. Maybe it will be a nice combo. Fingers crossed.

    On a side note, the methadone has completely relieved the pain from my ruptured disc so that's a plus.
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    #3
    Bluelight Crew BrokedownPalace's Avatar
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    While mixing benzos and z-drugs such as ambien with methadone is a bad idea, chances are if you keep the dose really low, you should make it through alright. It is just that the respiratory depression from the methadone will be exacerbated by other sedatives, so sleeping could prove to be fatal. not trying to scare you, but it is possible. you should be alright though since you took a relatively small dose of methadone. I assume you're sleeping by now? R e []D 0 R T back in the morning.
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    #4
    Quote Originally Posted by BrokedownPalace View Post
    While mixing benzos and z-drugs such as ambien with methadone is a bad idea, chances are if you keep the dose really low, you should make it through alright. It is just that the respiratory depression from the methadone will be exacerbated by other sedatives, so sleeping could prove to be fatal. not trying to scare you, but it is possible. you should be alright though since you took a relatively small dose of methadone. I assume you're sleeping by now? R e []D 0 R T back in the morning.
    Well, I survived. I took one Ambien CR 12.5 (chewed up) with 2 sudafed to help the resp depression. Waited about an hour and was still fine so I took another. Went to sleep about 30 minutes after that. Only a slight nod before I went to bed. (I WOULD NOT SUGGEST THIS TO ANYONE ELSE WHO DOESN"T HAVE A TOLERANCE TO ZOLPIDEM. I HAVE A VERY HIGH TOLERANCE)

    I think my opiate tolerance is quite a bit higher than I realized. I ended up taking a total of 15mg of methadone yesterday evening. I would say somewhere around the 2.5 to 3 hour mark I definitely felt it kick in. I would equate the feeling to taking maybe 4 Perc 10's on an empty stomach with some aspirin. After an hour or two that subsided to just a mild sedative feeling.
    Back pain is all gone though. It worked well for that. This morning I can still feel it a bit, but back pain is back. Considering taking another 10mg of methadone (that would be roughly 18 hours since first dose) to try to hit the back pain again. You think that would be ok? The pain management info I researched suggested 10mg q8h for someone with my tolerance, but I also don't want to get too much of this stuff in my system since I'm getting Perc 10's tomorrow and I don't want to block those out.

    By the way, thanks again for all your responses Brokedown. You've been very helpful.
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    #5
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    You can certainly take another 10mg methadone. I was about to say the same thing about you most likely having a tolerance to zolpidem, but it's probably best coming from the horse's mouth, as they say.

    10mg of methadone is a good starting dose for someone without opiate tolerance or with a small amount of tolerance. But since you took 15mg and didn't have a problem, 10mg should be fine. If you want to be extra careful about it, I recommend taking 5mg methadone, waiting two hours (methadone takes a LONG time to reach full effect) and if you're still in pain, taking the other 5mg.

    That low of a dose of methadone won't block the effects of your percocet's oxycodone. Based upon what I've read from others on this board...methadone doesn't really start blocking the effects of other opiates until the 50-70mg range. Myself personally I have very little methadone experience, I find it lasts a bit too long for my liking. Although it is ideal for pain management for that exact reason.

    Best of luck man, and keep us posted/let us know if you have any other questions.
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    #6
    Bluelighter StaySedated's Avatar
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    Touch the boys!


    Touch the boys!
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    #7
    Bluelight Crew BrokedownPalace's Avatar
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    Neighborhood pretty much covered it all, you should be good to go. No problem helping you out my dude. If you need anything else don't hesitate and ask.
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    #8
    Bluelighter StaySedated's Avatar
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    Touch the boys!


    Touch the boys!
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    #9
    Thanks Neighborhood and Brokedown. I took the 10mg not too long ago. We'll see how that goes. I'll report back in at the 2-3 hour mark. I posted a question on another thread related to the Methadone. If you get a chance give it a read. I'd appreciate your feedback.

    By the way, what the hell is up with this "TOUCH THE BOYS" guy?
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    #10
    Bluelighter StaySedated's Avatar
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    Quote Originally Posted by john3434 View Post
    By the way, what the hell is up with this "TOUCH THE BOYS" guy?
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    #11
    Quote Originally Posted by StaySedated View Post
    Thanks for inserting meaningless, nonsensical posts into a thread where I'm asking for answers to some serious questions. Really appreciate that man.
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