Chiming in here!
Since this is turning into the one of the wierdest, most disparate and at-times-combative threads I've ever seen on BL, I wanna chime in on a couple of things that are bothering me. From the recent looks of it most folks here are phoning in their partially thought out posts from waystations located in the hinterland limbo that is also known as "not-quite-baseline".
1)
And for the blessed knights of light not to attack you in such foolish manner.
Wow, Erny can you please recognize that it is not only you who is capable of offering timely and deep advice on tolerance, dose and experience? Cynicism will get you nowhere here. And more importantly, there is no need to rile up and rally the up-n-comers in some kinda "us vs them mentality" so that they view the Harm Reduction messages in a negative light (e.g. your "Blessed Knights of the Light who attack n00bs in a foolish manner]. Sure some responders go overboard, some give helpful details, and some help the young 'uns plot a course for future action and enlightenment.
It's all part of the community of BL, and each plays a role... Sometimes we even trade costumes and reverse roles. e.g. I like to give a heartfelt measured response, but sometimes I blast off on someone who is surely going to ruin a newly available and potentially world-changing molecule by doing stupid things and bringing it to the attention of the jack-booted thugs in black helicopters. Its all good man. Intricate the n00bs with us, don't extricate them to mordor.
2)
so my friends have 120mg of 25I-nbome freebase dissolved in 30ml of isopropyl alcohol.
they are now wondering what best to do with this.
they have a dropper which drops consistently pure isopropyl alcohol at 40 drops per ml.
since 1 ml of the solution contains 4mg of 25I-nbome, one drop should contain 100 micrograms of 25I-nbome. so 5 drops should be a reasonable 500 ug dose.
the question is how best to administer this.
Can you all please start presenting your inquiries and dilemnas in dimensional analysis form? Please? Pretty please with a cherry on top? It *really* provides a context-free way to see what the issue is and how to resolve it.
I'm not trying to dictate the mode of posting here, but it really and truly helps evolve the whole community towards a more succinct, less ambiguous form of communication.
Can we all try it please? The Key is that all extraneous details drop out, and all units except the final desired ones are eliminated.
So, accepting the volumetrics of your tools, we have:
(120mg 25I/30ml iPrOH)*(ml iPrOH/40 Drops) = 0.1 mg 25I/drop iPrOH
Ok, now that the plea for standardization of communicating dosages/volums and masses is out of the way... I'd like to give my opinion on the three options you developed.
Go with Number 1 (drop on blotter and use psykap's upper buccal ROA). This should get you there, and the idea of 0.5 mg (5 drops) per blot is a good starting place.
In formal form it looks like this:
(120mg 25I/30ml iPrOH)*(1ml iPrOH/40 Drops)*(5 drops/Blotter) = 0.5 mg/ Blotter
Frankly though, if it were me, I'd
dry down ~10 drops of the 25I-iPrOH solution (sol'n) in a small tube, leaving a residue that can be taken up/dissolved into a water/vinegar sol'n. This enables you to not dilute the overall sol'n further by adding water/vinegar sol'n to the 25I-iPrOH sol'n.
So, [PER USE @ 1 mg] dry down the 10 drops of 25I-iPrOH sol'n and take it back up/dissolve in 0.1 ml of 1:1 diluted vinegar (NOTE: 0.1 ml of 1:1 diluted vinegar = 4 of your drops using your calibrated dropper, which I calculate as 0.025 ml/drop, given your saying that you can count on 40 drops/ml). You can scale this up accordingly.
Formally [PER USE @ 1 mg]:
(0.1mg 25I/drop 25I-iPrOH sol'n)*(10 drops 25I-iPrOH/tube)[insert dry step here]*(1/0.1ml 1:1 vinegar water sol'n) = 1mg 25I-acetate in 0.1 ml 1:1 vinegar water sol'n. This is suitable for liquid insufflation of ~0.03 to 0.05 ml sol'n delivering 300-500 mcg 25I.