Does not matter much WHAT fluorine is bonded to, metabolically speaking. There ARE a few things that release the toxic fluoride ion, such as the inhalational anaesthetic halothane, where it can end up causing kidney damage if prolonged use is required.
But fluorine is a vicious bastard as far as elements go, in the elemental state, once it bonds, it really doesn't like to let go, highest electronegativity of any element, and just hungers for those valence bonding electrons, even in the case of otherwise near enough inert atoms with full valence shells, the autistic atoms out there, who really do not feel the need to bond with others, as their capacity for 'wanting' to form covalent bonds with another atom, is all but full, such as the noble gases, argon, krypton, neon, xenon, etc, not sure if a helium fluoride, or compound of any kind yet exists, but usually, those inert last period gases, the first compounds known of them, were fluorides, occasionally oxides, but usually no, it is usually the fluorinated derivatives of various kinds and made through exotic modes of synthesis, that is all due to the tremendous reactivity of fluorine.
(and in the elemental state, extreme toxicity, gaseous F2 in even extremely dilute concentrations will literally ignite flesh, and burn right through it thermally, not just corrosively, the corresponding hydrohalic acid, HF, is a weak acid, in the sense of PKa, as the reactivity of F means it doesn't dissociate nearly as well into its ionic species, in aqueous solution as does HCl, HBr, and HI, which get less electronegative as you move down the halogens, it stays tightly bound to its counterpart atom, H, shielding the acidic proton from being able to exist out in the open, so to speak, and lessening acidity.
That, results in something much much nastier than HCl, I have spilled concentrated HCl on me a good few times, and the absolute worst thing I have ever felt, is a little stinging, as it was promptly noticed and removed, and that is if it gets to sit on you, without being noticed for a few, although it will bleach and ruin your favourite clothes just perfectly, it doesn't cause severe burning easily via skin contact.
Contrast with an HF burn, which I have never experienced, but which is apparently incredibly painful, as whilst a weak acid, it gets to travel easily right through the skin, where it begins to react, and sequester calcium, mainly, but to a lesser degree other electrolytes, both from the blood, tissue and bones, yup, thats right, HF will seep through you, and leach the Ca2+ from your bones, causing an immense amount of pain in the process, causing the sludging out of the formed CaF2, which is quite insoluable in water and all the problems attending the sudden massive drop in serum calcium levels.
Working with HF in anything but the most diluted solutions, one must have intravenous and IM injectable forms of calcium gluconate, alongside a topical wash solution of the same, to be used if contact occurs, to provide a source of Ca2+ cation for the hydrofluoric acid to react with, that isn't the calcium in your blood and bones, and thus mitigate the toxicity by ensuring that less HF is left un-sated, to chew on one's tender, delicious bones
The carbon-fluorine bond is very, very strong however, and presents no such risks as attended by F2, or HF, the F in a fluorocarbon has sunk its teeth right in, and like a pitbull, won't let go, and it sure as hell isn't coming off as HF/fluoride ion in vivo.