It is a serotonin receptor antagonist among others, so I wouldn't risk it. Wait until you know it's out of your system, a half life of 6 hours is quite a long time.
Unless people can contest to successful rolls after using seroquel, I just highly doubt it since it blocks serotonin from working. I know it can kill lsd and shrooms trips, both of which are serotonin based. Then again, E works on completely different receptors, so you never know.