Bluelight

Thread: *New Suboxone film * official thread*

Page 2 of 41 FirstFirst 1234561222 ... LastLast
Results 26 to 50 of 1003
  1. Collapse Details
     
    #26
    Quote Originally Posted by Dankycodone View Post
    ^ Nice that is pretty interesting. White ink does not sound too healthy, JB I would not shoot that until you throughly research it.
    I don't know how many different pharmaceutical white inks there are, but here is one formulation that I found (in this case used on Clindamycin capsules):

    Opacode White S-1-7085 (pharmaceutical glaze modified, titanium dioxide, isopropyl alcohol, ammonium hydroxide, propylene glycol, n-butyl alcohol and dimethylpolysiloxane).
    Source: http://www.drugstorepharmacy.ca/medi...d_name_id=4723


    And this one, from Sigma Cilicaine VK Penicillin Capsules:

    Negligible quantities of the following ingredients are present in the white ink used to write the name SIGMA: Pharmaceutical glaze USP/NF, titanium dioxide, isopropyl alcohol, ammonium hydroxide, propylene glycol, butan-1-ol and dimethicone
    Source: http://www.emedical.com.au/default.a...6&itemID=10612

    I'd imagine most white pharamceutical inks are similar in contents...they probably all have titanium dioxide as a major component. It is my guess that since the solvents are evaporated as the ink dries, you are left with the glaze, TiO2, and dimethicone. They are present in such small amounts that I would be surprised if any harm were to come from injection, especially after micro-filtering. I'd like to know a little more about the glaze though!
    Reply With Quote
     

  2. Collapse Details
     
    #27
    Bluelighter homeydontplaythat's Avatar
    Join Date
    Dec 2009
    Location
    LOS ANGELES
    Posts
    1,245
    the tablets have lemon/lime flavor. the strips have just lime.

    james, you are saying they taste exactly the same though?

    also, how quickly do hey dissolve in water when prepped for IV? did you have to use heat to expedite?
    Reply With Quote
     

  3. Collapse Details
     
    #28
    Quote Originally Posted by homeydontplaythat View Post
    the tablets have lemon/lime flavor. the strips have just lime.

    james, you are saying they taste exactly the same though?

    also, how quickly do hey dissolve in water when prepped for IV? did you have to use heat to expedite?
    Do not heat......also, im pretty sure the strips also have lemon lime. Im gonna go check my source real quick on that one....
    Reply With Quote
     

  4. Collapse Details
     
    #29
    NVM....looks like you were right, tablets have lemon lime flavor, strips have just lime. Allthough, like I said, they tasted pretty much the exact same to me. They just felt different.
    Reply With Quote
     

  5. Collapse Details
     
    #30
    My first question was what's the ba?

    Only thing I found in the 3rd link submitted by tchort:
    Because of the potentially greater relative bioavailability of SUBOXONE sublingual film compared to SUBOXONE (buprenorphine and naloxone) sublingual tablets, patients switching from SUBOXONE (buprenorphine and naloxone) sub- lingual tablets to SUBOXONE sublingual film should be monitored for over-medication. Those switching from SUBOXONE sublingual film to SUBOXONE (buprenorphine and naloxone) sublingual tablets should be monitored for withdrawal or other indications of under-dosing. In clinical studies, pharmacokinetics of SUBOXONE sublingual film was similar to the respective dosage strengths of SUBOXONE (buprenorphine and naloxone) sublingual tablets, although not all doses and dose combinations met bioequivalence criteria.
    Reply With Quote
     

  6. Collapse Details
     
    #31
    Bluelighter homeydontplaythat's Avatar
    Join Date
    Dec 2009
    Location
    LOS ANGELES
    Posts
    1,245
    awesome! makes total sense, you dont have all that gunk oozing out and you wont swallow as much of it. definetly should have a better BA. with less material they should dissolve much faster too, giving a quicker onset. man, i may just have to switch over.

    how long do they take to dissolve when you hit em with water for IV?
    Reply With Quote
     

  7. Collapse Details
     
    #32
    Quote Originally Posted by keeb333 View Post
    I don't know how many different pharmaceutical white inks there are, but here is one formulation that I found (in this case used on Clindamycin capsules):



    Source: http://www.drugstorepharmacy.ca/medi...d_name_id=4723


    And this one, from Sigma Cilicaine VK Penicillin Capsules:


    Source: http://www.emedical.com.au/default.a...6&itemID=10612

    I'd imagine most white pharamceutical inks are similar in contents...they probably all have titanium dioxide as a major component. It is my guess that since the solvents are evaporated as the ink dries, you are left with the glaze, TiO2, and dimethicone. They are present in such small amounts that I would be surprised if any harm were to come from injection, especially after micro-filtering. I'd like to know a little more about the glaze though!
    Very interesting. Thanks for the reply dude.
    Reply With Quote
     

  8. Collapse Details
     
    #33
    My Dr was telling me the discount cards are good for six months, there is no plan to release a subutex strip in the forseeable future. I asked if they were getting rid of the pills and she said no, in fact they recommend using the pill formulation for induction, so BA must be pretty close IMO. Im not takng sub now, if I got back on a small doses Id definitely go for the strips due to the ease of cutting them up. I'm not so sure this is the future of meds or just an attempt to provide additional child proofing packaging to appease the DEA. My Dr said only one of her patients were into the strips, because of the $75 coupon, I figured all of them would want to switch, although you'd be srewed if you like to snort your bupe.
    Reply With Quote
     

  9. Collapse Details
     
    #34
    BL Ambassador Captain.Heroin's Avatar
    Join Date
    Nov 2008
    Location
    I wished with all my heart that we could just...leave this world behind. Rise like two angels in the night and magically...disappear.
    Posts
    48,418
    Quote Originally Posted by Dankycodone View Post
    ^ Nice that is pretty interesting. White ink does not sound too healthy, JB I would not shoot that until you throughly research it.
    You can avoid the white ink on the Suboxone strips (it's not homogenized into the strip), all you have to do is cut the part with the dosage indication off, or just scrape off the white ink.
    Reply With Quote
     

  10. Collapse Details
     
    #35
    I'm really interested in these, I'll post the e-mail and links I got today for everyone in a second.
    NSFW:
    f you're working to overcome opioid dependence, you know the experience can sometimes be overwhelming. That's why the formulation of your medication should help make your experience convenient. Some patients have shared their concerns about taking SUBOXONE® (buprenorphine and naloxone) sublingual tablets (CIII), such as:

    The time the tablets take to dissolve
    The difficulty of traveling with them
    Their taste

    Consider a treatment that may make your experience more comfortable and convenient.
    SUBOXONE Film

    , a new formulation of SUBOXONE, may improve your daily treatment experience. And clinical trial patients tell us they prefer SUBOXONE Film to the SUBOXONE Tablet.1a

    SUBOXONE Film is indicated for long-term treatment of opioid dependence and should be used as part of a complete treatment plan that includes counseling and support.

    SUBOXONE Film delivers:

    An evolved patient experience
    - Faster to dissolve than SUBOXONE Tablet1b
    - A favorable taste rating (more than 71% of patients scored the taste as neutral or better)1c
    - Individually wrapped in compact unit-dose pouches that are child-resistant1d and easy to carry1e
    - Once-daily dosing (just like the SUBOXONE Tablet)2
    - Clinically interchangeable with SUBOXONE Tablet, so your doctor can transition you. Your doctor should monitor you for overmedication3
    Built-in support from the Here to Help® Program that can help make treatment success more likely4

    Experience exclusive savings
    Only SUBOXONE Film offers savings on your prescription of up to $75* per month if eligible. Download your savings card

    now and take it to your next doctor appointment.
    *Click here for details



    Call for an appointment today
    To experience SUBOXONE Film—and take advantage of the savings—you will need a prescription for SUBOXONE Film. If you haven't made an appointment yet, don't wait. Ask your doctor whether you can improve your treatment experience by changing to SUBOXONE Film

    .

    Keep in mind that physical dependence is just one part of the story. Your relationships, thoughts, and daily routines are all tied together. That's why counseling

    is such a critical part of your treatment. And why the Here to Help Program may be too. Here to Help has been shown to increase the likelihood you'll stay in medication-assisted treatment, which can help lead to better treatment success.4

    You should know: As with other opioids, buprenorphine can be abused. It's essential that your doctor monitor your use of SUBOXONE Film to help you achieve and maintain stability. You should also expect to make regular follow-up visits, especially if your doctor prescribes multiple refills.

    The Here to Help Program

    is only for people who are in treatment with SUBOXONE Film.

    Share
    Know someone who is opioid dependent? Help them start their own treatment story. Tell them

    about SUBOXONE Film.

    Best regards,

    The Here to Help Team

    866-973-HERE (4373)

    Important Safety Information

    SUBOXONE® (buprenorphine and naloxone) Sublingual Film (CIII) is indicated for maintenance treatment of opioid dependence as part of a complete treatment plan to include counseling and psychosocial support. Treatment should be initiated under the direction of physicians qualified under the Drug Addiction Treatment Act.

    SUBOXONE® (buprenorphine HCl/naloxone HCl dihydrate sublingual tablets) (CIII) is indicated for the treatment of opioid dependence.

    SUBOXONE Sublingual Film and SUBOXONE Sublingual Tablets should not be used by patients hypersensitive to buprenorphine or naloxone.

    SUBOXONE Sublingual Film and SUBOXONE Sublingual Tablets can be abused in a manner similar to other opioids, legal or illicit. Clinical monitoring appropriate to the patient's level of stability is essential.

    Chronic use of buprenorphine can cause physical dependence. A sudden or rapid decrease in dose may result in an opioid withdrawal syndrome that is typically milder than seen with full agonists and may be delayed in onset.

    SUBOXONE Sublingual Film and SUBOXONE Sublingual Tablets can cause serious life-threatening respiratory depression and death, particularly when taken by the intravenous (IV) route in combination with benzodiazepines or other central nervous system (CNS) depressants (ie, sedatives, tranquilizers, or alcohol). It is extremely dangerous to self-administer nonprescribed benzodiazepines or other CNS depressants while taking SUBOXONE Sublingual Film or SUBOXONE Sublingual Tablets. Dose reduction of CNS depressants, SUBOXONE Sublingual Film and SUBOXONE Sublingual Tablets, or both when both are being taken should be considered.

    Liver function should be monitored before and during treatment.

    Death has been reported in nontolerant, nondependent individuals, especially in the presence of CNS depressants.

    Children who take SUBOXONE Sublingual Film or SUBOXONE Sublingual Tablets can have severe, possibly fatal, respiratory depression. Emergency medical care is critical. Keep SUBOXONE Sublingual Film and SUBOXONE Sublingual Tablets out of the sight and reach of children.

    Intravenous misuse or taking SUBOXONE Sublingual Film or SUBOXONE Sublingual Tablets before the effects of full-agonist opioids (eg, heroin, hydrocodone, methadone, morphine, oxycodone) have subsided is highly likely to cause opioid withdrawal symptoms.

    Neonatal withdrawal has been reported. Use of SUBOXONE Sublingual Film or SUBOXONE Sublingual Tablets in pregnant women or during breast-feeding should only be considered if the potential benefit justifies the potential risk. Caution should be exercised when driving vehicles or operating hazardous machinery, especially during dose adjustment.

    Adverse events commonly observed during clinical trials and postmarketing experience for SUBOXONE Sublingual Tablets are headache, nausea, vomiting, sweating, constipation, signs and symptoms of withdrawal, insomnia, pain, and swelling of the limbs.

    Adverse events commonly observed with the sublingual administration of SUBOXONE Sublingual Film are numb mouth, sore tongue, redness of the mouth, headache, nausea, vomiting, sweating, constipation, signs and symptoms of withdrawal, insomnia, pain, swelling of the limbs, disturbance of attention, palpitations, and blurred vision.

    Cytolytic hepatitis, jaundice, and allergic reactions, including anaphylactic shock, have been reported.

    This is not a complete list of potential adverse events associated with SUBOXONE Sublingual Film and SUBOXONE Sublingual Tablets. Please see full Product Information for a complete list.

    To report an adverse event associated with taking SUBOXONE Sublingual Film or SUBOXONE Sublingual Tablets, please call 1-877-782-6966. You are encouraged to report adverse events of prescription drugs to the FDA. Visit www.fda.gov/medwatch

    or call 1-800-FDA-1088.

    Please see full Product Information

    and Medication Guide

    for SUBOXONE Film

    For more about SUBOXONE Tablet, please see full Product Information

    Questions: When sniffing something does it have to be in the nostrils, or are the membranes further back. Because it would be easy to put the strip in your nose, and it would dissolve, but if it had to be far back it might cause a problem.

    This seems great for IV, I haven't looked at all the ingredients, but so far this is looking promising, I might ask to switch if I can still sniff.
    Reply With Quote
     

  11. Collapse Details
     
    #36
    Bluelighter homeydontplaythat's Avatar
    Join Date
    Dec 2009
    Location
    LOS ANGELES
    Posts
    1,245
    i wonder if you could put them on a wet band aid on your balls. i kid, i kid.
    Reply With Quote
     

  12. Collapse Details
     
    #37
    Quote Originally Posted by JamtasticX View Post
    I'm really interested in these, I'll post the e-mail and links I got today for everyone in a second.

    Questions: When sniffing something does it have to be in the nostrils, or are the membranes further back. Because it would be easy to put the strip in your nose, and it would dissolve, but if it had to be far back it might cause a problem.
    This seems great for IV, I haven't looked at all the ingredients, but so far this is looking promising, I might ask to switch if I can still sniff.
    I think it would be simpler to make liquid nasal spray solution out of the strips in order to administer them intranasally. I think this would also be much easier on your nostrils membranes, as well as your lungs.....becuase the drug will be dissolved inside a liquid, therefore it is less likely to float through the air and end up in your lungs, and more likely to stay inside the water, stuck to your noses membranes. Allthough, sticking the strip in your nose may work a well, but I think making a "nasal spray" solution would be more efficient. Just make sure you use anti-bacterial water.

    Also....yes, the strips do work well for IV. They have MUCH less fillers and binders in them to worry about. Allthough that shouldnt be much of an issue if you use a micron filter like you should. But for most of us who dont have easy access to micron filters, these strips may prove to be a much healthier alternative to the "talc filled" pills.
    Reply With Quote
     

  13. Collapse Details
     
    #38
    Bluelighter lightofmeaning's Avatar
    Join Date
    Jun 2010
    Location
    7 1/2 floor
    Posts
    4,524
    ive been on sub for a long time. i have a fairly simple question. i dislike the buzz from sub so i snort a very small amount in the am and before bed, just enuff to kill the wd's. one pill will last me around a week. since these come in sealed packs will they degrade or dissolve once they are open.

    if i take the same dose and have the strip out of the pack for a week will it lose potency or will i have any other problems. i was told they degrade once open. i didnt know if it was true or b/s.

    thanks
    Reply With Quote
     

  14. Collapse Details
     
    #39
    They more than likely degrade much quicker than the tablets would because there is MUCH less fillers and binders to protect the active chemicals from the elements. The strips dont really have much protecting them from heat, moisture, light, etc....so it would be best to try to "seal" them up in something else(or even back in the same package) in order to prevent any decomp. They were made to be used all at once so I doubt there are any "preservatives" in place to help prevent decompostion once opened.

    Just do your best to keep them away from the elements and im sure you will not notice any degredation in the quality of the suboxone.

    Since these strips are so new, only time will tell how well they do outside of there packaging for relatively long periods of time.
    Reply With Quote
     

  15. Collapse Details
     
    #40
    So do you all think they ARE safe to shoot?
    Reply With Quote
     

  16. Collapse Details
    Subs/shoot=NO! 
    #41
    No they are not safe to shoot because they contain Naloxone so if you shoot them it will send you in to full withdrawl. Any body who has a sub film perscription ask your doctor for the 75$ off card or print it on the suboxone website. it will be much cheaper.Also, you can cut the 8mg strips into pieces and they last and still work just fine.
    Reply With Quote
     

  17. Collapse Details
     
    #42
    Quote Originally Posted by leahD View Post
    No they are not safe to shoot because they contain Naloxone so if you shoot them it will send you in to full withdrawl. Any body who has a sub film perscription ask your doctor for the 75$ off card or print it on the suboxone website. it will be much cheaper.Also, you can cut the 8mg strips into pieces and they last and still work just fine.
    HAHHA...thr nalaxone doesnt do ANYTHING. You CAN Inject these strips just like you can inject the pills. Ive been injecting the pills 3 times a day for months now and not once have I gone into withdrawals. In fact, it ives me a euphoric rush. I think you need to do some reading about suboxone on BL before you start making posts like that. Im not trying to be rude but that is just blatantantly false.

    There are MANY MANY people on this website that inject there suboxone on a daily basis, which proves what you are saying wrong. I really am not trying to be rude here its jsut that I can tell by what you said that you have done VERY LITTLE research on whether or not that statement you made is true or false.....and I think its important before you post, to make sure what your saying makes sense, as to not spread false information, especially through the BL community, which is full of people looking for answers to questions, and they expect those answers to be truthfull.
    Last edited by jamesBrown; 02-10-2010 at 06:35.
    Reply With Quote
     

  18. Collapse Details
     
    #43
    Greenlighter
    Join Date
    Oct 2010
    Location
    around the sun
    Posts
    28
    I'm Rather stoked I am on subutex I really feel bad for you guys with these films they prolly gonnan suck anyway./.. GEt on subutex if you can its cheaper and better all around wont make you sick or depressed like Suboxone does cuz of shitty Naloxone

    Good luck to everyone
    Reply With Quote
     

  19. Collapse Details
     
    #44
    Quote Originally Posted by SubutexMan View Post
    I'm Rather stoked I am on subutex I really feel bad for you guys with these films they prolly gonnan suck anyway./.. GEt on subutex if you can its cheaper and better all around wont make you sick or depressed like Suboxone does cuz of shitty Naloxone

    Good luck to everyone
    Actually, the suboxone gives me euphoria, energy, and acts as an anti-depressant......i am more than happy taking my suboxone. Of course I dont take it as prescribed. I only take 0.5mg doses so that bupernorphines full agonist metabolite norbupernorphine can bind to my brains open receptors and give me all these euphoric and beneficial effects. the nalaxone is comletely inactive and i have never had any problems with it.
    Reply With Quote
     

  20. Collapse Details
     
    #45
    Bluelighter homeydontplaythat's Avatar
    Join Date
    Dec 2009
    Location
    LOS ANGELES
    Posts
    1,245
    dont you mean euphorical effects? haha, sorry, couldnt help it.
    Reply With Quote
     

  21. Collapse Details
     
    #46
    BL Ambassador Captain.Heroin's Avatar
    Join Date
    Nov 2008
    Location
    I wished with all my heart that we could just...leave this world behind. Rise like two angels in the night and magically...disappear.
    Posts
    48,418
    Quote Originally Posted by SubutexMan View Post
    I'm Rather stoked I am on subutex I really feel bad for you guys with these films they prolly gonnan suck anyway./.. GEt on subutex if you can its cheaper and better all around wont make you sick or depressed like Suboxone does cuz of shitty Naloxone

    Good luck to everyone
    Not everyone reacts negatively to Suboxone.
    Reply With Quote
     

  22. Collapse Details
     
    #47
    Bluelighter homeydontplaythat's Avatar
    Join Date
    Dec 2009
    Location
    LOS ANGELES
    Posts
    1,245
    yeah naloxone does suck ass, but its really not that noticeable with suboxone. sometimes if you take too much you do get a headache. wow, im fucked up.
    Reply With Quote
     

  23. Collapse Details
     
    #48
    I just switched to the strips yesterday after seeing my doctor. The topic of the new formulation film was brought up almost immediately, and I was given a choice to try them out. Including the $75 discount card and no insurance I paid ~$35 for 10 strips. I found them to dissolve in about 1/4 of the time it takes for me when taking suboxone tablets, less than 5 minutes. To my disappointment the film was exactly the same taste as the tablets. Either way I was much happier; it look a lot less time to dose and created hardly ANY residual "fluid" in ones mouth as the tablets do. I do not, in my experience, feel that the BA for the film is really much higher than the tablets. Hope this helps
    Reply With Quote
     

  24. Collapse Details
     
    #49
    Quote Originally Posted by scarletbegonias View Post
    I just switched to the strips yesterday after seeing my doctor. The topic of the new formulation film was brought up almost immediately, and I was given a choice to try them out. Including the $75 discount card and no insurance I paid ~$35 for 10 strips. I found them to dissolve in about 1/4 of the time it takes for me when taking suboxone tablets, less than 5 minutes. To my disappointment the film was exactly the same taste as the tablets. Either way I was much happier; it look a lot less time to dose and created hardly ANY residual "fluid" in ones mouth as the tablets do. I do not, in my experience, feel that the BA for the film is really much higher than the tablets. Hope this helps
    im glad that you are happy about switch to the strips. And I know exactly what you are talking about with the whole having a shitload of saliva in your mouth from letting the tablets dissolve. Allthough, I found that if I crushed the pill up before I put it under my tounge, it would dissolve extremely quickly, and that would be much less of an issue.

    As far as the bioavailability goes......im pretty sure the strips for some reason actually DO have a slightly higher BA, but since most people are taking such high doses of suboxone, any increase in the BA wouldnt result in you noticing any different effect from the drug. Just like taking more and more sub than your prescribed dose will not increase the effects.
    Reply With Quote
     

  25. Collapse Details
     
    #50
    Bluelighter
    Join Date
    Mar 2010
    Location
    Minneapolis, Middlewest
    Posts
    254
    Quote Originally Posted by scarletbegonias View Post
    I just switched to the strips yesterday after seeing my doctor. The topic of the new formulation film was brought up almost immediately, and I was given a choice to try them out. Including the $75 discount card and no insurance I paid ~$35 for 10 strips. I found them to dissolve in about 1/4 of the time it takes for me when taking suboxone tablets, less than 5 minutes. To my disappointment the film was exactly the same taste as the tablets. Either way I was much happier; it look a lot less time to dose and created hardly ANY residual "fluid" in ones mouth as the tablets do. I do not, in my experience, feel that the BA for the film is really much higher than the tablets. Hope this helps
    My doc gave me the exact same thing. The $75 discount card! Haha!


    Here's my reaction to the strips:

    As some of you may know, I've been binging on H for a good two months, going on two and a half. So as I talk myself into going back on Subs I think, "and this time I have the strips!"

    It becomes fairly apparent that the strips are far more convenient than anything. It takes them about one minute to fully dissolve (if I've taken a sip of water beforehand) and after that I leave them in there for about the same amount of time as I would with the pills (5-10 minutes), to make sure that I get it all absorbed. I was still feeling like shit despite taking around 8mgs over a four hour period, so I decided to booty-bang (rectal ROA) another 4mgs. When I prepared the strips in my modified syringe, it would seem that they didn't want to dissolve as quickly as they did in my mouth. It took a full 10 minutes before they were dissolved enough to administer. I don't know if a whole lot of bupe even ended up in the water in my modified rig.

    I used to snort my bupe occasionally, which is kind of a downer with these new strips. I didn't really do it enough to the point where I'm really disappointed with the strips. Overall it seems that the strips are simply a matter of convenience for people who choose to use the sublingual ROA. They certainly do trump the tablets in that respect, and I do notice a slight difference in the "feel" of 2mg sublingually on the films vs 2mg sublingually with the pills. The bioavailability does feel higher. However, I think if the cost of the strips isn't equal to the cost of the pills after I use up my discount, I'll probably just go back to the pills as a matter of cost.

    And oh yes. . . the flavor is exactly the same, to those who've been discussing and bickering about it. The only thing a little different is the after taste, which is slightly 'chemical.'
    Reply With Quote
     

Page 2 of 41 FirstFirst 1234561222 ... LastLast

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •