N&PD Moderators: Skorpio | thegreenhand
From wikipedia : "Drugs known to be sigma agonists include cocaine,diacetylmorphine, PCP, fluvoxamine, methamphetamine, dextromethorphan, and the herbal antidepressant berberine. "
I wonder if DMT is also a sigma agonist. You may be on to something...
-lenses
ITT: what is a "bell-ringer"? To what extent is that induced by rapid administration of cocaine similar to or different from other drugs with strong auditory effects?
ebola
PCP’s bellringer is the opposite of a ringing in the ear, it is a wave of silence, then mass anesthesia...
would shooting heroin produce any momentary rise in blood pressure? cuz i have gotten tunnel vision and a feeling of silence kind of like a bellringer after shooting dope. i was thinking the rise in blood pressure could be a few-second stress response from the anticipation and physical stress of poking one's self with a needle.
I wonder if it's from sigma agonism?
I always get a ringer from smoking DMT, another sigma agonist.