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    will lyrica help with opiate withdrawal? 
    #1
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    Well yaa so my question is pretty basic. I've never taken Lyrica but I have access to it. I'm going to start my detox today (2-5 bag a day). I don't know if Lyrica works on other receptors like Tramadol does or even if Lyrica is an opiate at all. One time I took a bunch of benadryl (can't remember how much exactly) to combat opiate withdrawals, that was a bad idea because it just threw me in a hazey hell hole that did more damage than good. If anyone is familiar with Lyrica tell me a good dose too, I mean I've read up on it here and 600mg sounds good???
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    #2
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    Can you not try tapering your dose down a little before you detox.

    When I realise its time to get back on subutex, I always go 3-4 days on just 1 - 1.5 bags a day. I find it seems to help quite a lot rather than just jumping off at 5 bags a day.
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    #3
    Bluelighter woamotive's Avatar
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    I don't think it's an opiate. However, I do believe it can make opiate withdrawal a bit more do-able. Kind of like a benzo would. In other words, it'll make you feel a little better and forget (not forget-as that's impossible, but loosen up a bit and tend not to focus as much on) about the w/d's. I think it's worth a shot trying.
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    #4
    Bluelighter thelung's Avatar
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    It isn't an opiate. It will help some of the withdrawl though. I quite like Lyrica myself.
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    #5
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    Thanks for the help guys. Ya I have been tapering last two days I've only done a bag just to scrape by.
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    #6
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    Works on similar recptors to benzos so the anxiety will be lower. Physical WD will be the same though cause its not an opiate. Start low, like 25mg-50mg three times a day and taper up the lyrica as the WD gets worst. Try not to go over 300mg a day and space your doses every 4-6 hours but if they help you could probably push it up to 600mg a day. Make sure you taper down the lyrica when you start to feel better. Best of luck mate, hope you get through it.
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    #7
    I have access to a lot of lyrica, and have been trying to quit opioids for a while. I use Oxymorphone and morphine. I went from 200mgs im of morphine to nothing about 3 days ago. I have been taking 150mg of lyrica every 8 hours religously. I have not thrown up, had the chills or night sweats or that overall feeling of ickyness. I usually have really bad withdrawls from the stuff so i can say that the lyrica is definately working on me. Will have to see how it goes from here. I am just a little shakey, but i would be moreso without it!
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    #8
    wow, that's great to hear opana man! i'm sure anyone here addicted to opiates or potentially facing w/ds likes to hear encouraging experiences about using other meds to effectively decrease the symptoms.
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    #9
    Bluelighter K'd-OUT-in-AZ's Avatar
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    Lyrica DOES help opioid withdrawals. It reduces the anxiety symptoms and even though it isn't an opiate, it does help with some of the pain. Also helps for insomnia. Doses like 450-600mg are helpful.
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    #10
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    I Love Lyrica and yes it helps with the opiate withdrawals. Lyrica is a schedule V controlled substance. while it is not an opiate be careful with higher doses. This drug will put you in a blackout if you take enough. One note I would like to make that I feel is extremely important. Do not mix Lyrica with methadone. And do not mix Lyrica with Benzo's. These are deadly combinations. My wife died from mixing a relatively small dose of klonopine and lyrica. Methadone users are familiar with the paper you sign not to mix methadone with xanax right? Well I am a firm beliver that that same form should exist with Lyica and methadone. A deadly combination.
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    #11
    Yes lyrica is a miracle drug and helps with both opiate and benzo withdrawls, I would say it cures the dope sickm it is truely amazing, i was on a bundle a day and then about 20 percocets a day for 2 weeks and just quit because SWIM has a urine test coming up and i took about 600 mg of lyrica and i cant even tell im dope sick SWIM is not puking or shitting and in any pain.
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    #12
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    I love taking Lyrica,but I find taking it 5 or so days in a row you build a tolerance very quick, for me it's one of those drugs that after a while you can't tell you are taking it,but you can sure tell if you miss a dose. I have a close friend who always says higher doses like 300 mgs and up help with his methadone withdrawels. I am rx'ed 900 mg's a day for nerve pain but do not take it everyday. I try to take it about once a week and have a "happy day". If I hurt and can't sleep I will take it but my nerve pain seems to be getting better on it's own. I also take methadone daily and am thinking of stock piling m lyrica if it really does help in case there ever comes a day I have to stop the methadone.I take 85 mg's of methadone a day.That may by why I don't have leg pains anymore too I am glad I found thid thread because my buddy has been telling me they help methadone w/d's forever!
    Last edited by ganeal; 08-02-2012 at 12:58. Reason: error
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    #13
    Bluelighter Ohayou's Avatar
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    Lyrica? I'll have to try this. What effects does it usually have? Are benzos still better?
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    #14
    Greenlighter Swim 1211's Avatar
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    Lyrica absolutely helps if not completely eliminates opiate withdrawal symptoms.. I kind of have a high tolerance to it so I take 1000-1200mgs at night to sleep and 500-600 mgs during the day.. But for first time users I'd think 300 mgs during the day and 700-800 mgd at night would be good...but keep I'm mind high doses of lyrica makes you very intoxicated feeling, you lose control of motor skills and get a deep body buzz..pretty damn cool actually .. As long as you have nothing to do lol
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    #15
    Greenlighter Swim 1211's Avatar
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    I forgot to add that it takes about 1 1/2 hours for the lyrica to start to kick in and it lasts a good 12 hours..
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    #16
    Be careful using Lyrica..... Especially if not tapering up. People have literally blacked out and fallen like a board onto the cement if they didnt taper up. Last time the dosage was 200mg's (The largest made single unit). The 135 pound guy literally was fine then BOOM.......
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    #17
    Bluelighter travisr's Avatar
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    It works pretty good for opiate withdrawals. I was on 15-50mg of oxy ir for a long time, switching between hydrocodone whenever I couldn't get the oxys. I'm rx'ed 200mg of lyrica twice a day. I stopped a few times with the lyrica, but relapsed a few times. I stopped the oyxs on Friday, took 400 mg, because I have a tolerance, stopped all the withdrawal!! Today is Saturday night, and I took about 600mg today, and still feel fine, no physical withdrawal just some back pain, I do stretching and take some Advil, and Tylenol it helps. It really makes me tired, keep yawning all day, and feels "drunky" but much better than the withdrawal from the pills. Hopefully this is the final time I do this to myself, its gonna be rough but manageable with the lyrica!!
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    #18
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    yes it works. It istn magic, is not going the WD to disappear, but it lows the WD, like if, from 0 to 10 you are on a 7 WD, after lyrica you may feel it like 4 or 5 . Catapresan also works, and Codeine also works even thats an oppie so a fast "coming down" with codeine is smart, unless you want your WD coming longer

    but yeah, lyrica works with some of the WD symptons. I feel my anxiety comes down with lyrica, pe
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    #19
    Bluelighter Tryptamite's Avatar
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    Lyrica is amazing for opiate WDs in high doses, like 450-600mg +. Nearly makes all the symptoms disappear for me. But not so good for long WDs like methadone. The lyrica is addictive in itself and should not be used consequetively for more than a week. Also tolerance builds fast and the effect becomes less and less helpful each day.

    Use for the worst of the WDs and discontinue use. Use benzos for a couple of days after and finish med regime.

    I used lyrica too much to come off a Xanax binge. Now I am nearly at the end of a taper. I can tell you it is definately addictive physically,
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    #20
    I know this post is years old but my pain mgmt has me on oxy, opana, lyrica and xanax. I've never had a problem at all other than it does get me tired at ten pm but after working all I find that normal. That is just my experience so be carefull!
    robcr11@gmail.com
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    #21
    Hello,I am currently 5 days off 10/325 Hydroncodone and 50 mg (2 pills 2x day) I am using Lyricia and it seems to be helping. I wa prescribed 75 mgs 2x day. Obviously, I am taking more. Good Luck!
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    #22
    Random bump.

    Just coming off 24mg buprenorphine been taking 300mg pregabalin twice daily and my prescribed lofexidine and the withdrawal has been almost nil so far. Just waking up for day four (really early) and bumped the dosage up to 600mg probably three times a day (due to the short half life) as I approach the point where I essentially have none of the bupe in me (5 half lives). So far I'm completely fine though really.

    Surely this drug is going to be licensed and used for opiate withdrawal at some point.
    Last edited by omen_owen mk2; 31-05-2014 at 08:15.
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    #23
    It depends on your tolerance, but yeah, it certainly helps.

    I would like to add that gabapentin itself(which pregabalin, aka lyrica is derived from) also helps opioid withdrawals, mainly because it helps RLS, and high doses can (somewhat) relax you, though of course, lyrica is better.
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    #24
    I have been on a very low dosage of methadone for 2 years. Today I am cutting down from 7.5 to 5mg a day. I took 2.5mg of methadone and .5mg of xanax this morning at the same time. I can feel the effects of the xanax so far. Took both about 45 min ago. I obviously have a tolerance to methadone. But I am new to taking benzos. I was taking 1 or 1.5mg of ativan for a few days before I ran out so I switched to xanax. Is this an Ok combination considering I have a tolerance to methadone but not so much with benzos. I'm kinda paranoid and want to make sure 2.5mg of methadone and .5mg of xanax is ok.
    Thanks for your Help.
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    #25
    I have been doing the opiate thing for about 7 years now and after some time you really put a lot of effort into finding things to help with withdrawal, although it always ends up just being a bridge to help me along until I can do opiates again I have found some things that work. Some of these things could probably help somebody quit if they really wanted to / needed to. I won't cover all of them, just the ones that pertain to this thread. I'll address Gabapentin (neurontin) and Pregabalin (Lyrica). I have used both and find these two drugs to be the most effective drugs to treat withdrawal. I'm not counting things like suboxone, tramadol, or codeine because that is retarded because they are all opiates (or partial opiates) so you might as well just be doing oxys or hydros and saying that they are helping your withdrawal. Well no shit, thats because they are opiates.

    Okay so to get to my point. Lets talk about Gabapentin first. This drug has limited effectiveness when it comes to treating opiate withdrawal. They come in 100, 300, and 400 mg capsules and 600 and 800 mg extended release tablets. In order for Gabapentin to help with withdrawal you need to take high doses. (at least 900 mg, but 1500-3000) for maximum effectiveness. I want to add that for me, for whatever reason the capsules dont work worth a crap. I can take 2-3 grams of capsules and it helps a little bit but Ill still have the runs, the sneezes, the hot flashes. It helps with the appetite a little and helps with the other symptoms I mentioned marginally. The 600 and 800 mg tablets seem to work better for whatever reason. Over all though lets say you are in full blown opiate withdrawal from a decent habit lets go with 80-100mg of oxy a day. You are at a 10 on a scale of 1-10 on the opiate withdrawal scale. The Gabapentin will take you from a 10 to like a 5 on the first day you use them, but tolerance builds fast after a few days gabapentin barely works and might bring you from like a 10 to an 8.

    Now lets talk about Lyrica. I fucking love lyrica! it comes in 25, 50, 75, 100, 150, 225 and 300 mg capsule. Lyrica works great for withdrawal. The first 3 days of withdrawal always are the worst IMO and the first is always pretty bad and when the anxiety is the worst because you know all hell is about to break loose. Lyrica has taken me from a 10 on the opiate withdrawal scale to like a -5. I will go from feeling like dog crap to feeling high as a kite. Unfortunately this is only the case for one day for me. I will usually take about 500 mg of lyrica in order to achieve this effect. However, if I take 500 mg for the second day in a row it kind of just makes me sleepy and works on about the same level as gabapentin (well a little better) but youll wanna double your dose each day to get continuous help from the lyrica.

    After about 3 or 4 days help from either of the drugs in minimal, but you should be through the worst of your withdrawal anyways (or have found some smack), if you dont have a huge benzo tolerance you could pick up some xanax, klonopin or valium to help out as they are similar and work on the same (GABA) receptors as the lyrica and gabapentin. With my gigantic benzo tolerance (10mg of xanax doesnt even effect me ) I find benzos to be not helpful at all besides to help sleep during detox.

    As others have mentioned it takes about 2 hours for Lyrica to start working (same goes for gabapentin) and lyrica can really fuck you up. I got fired for going to work on lyrica once because I was falling into things and slurring my speech (oopsy daisy). Doses of higher than 800 mg can be excessive and will probably just lead to you passing out for 16+ hours.

    Lyrica is the best drug for opiate withdrawal. I am coming to the end of a pretty good H binge right now. Just got up and did a vicodin. I have 20 of the 100 mg lyricas right now so I'm going to take 4 or 5 of them and enjoy my day.
    Last edited by blazequietly; 10-04-2015 at 17:22. Reason: typos
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