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5-HTP Basic Questions, The Positive v.s. Negative Effects

muie

muie

Bluelighter
Joined
Dec 18, 2008
Messages
849
There wasn't much info on this as I originally hoped so I'm asking a few questions here:

1. Are there any precautions that need to be taken when you start 5-HTP? Besides seratoninergic drugs should you avoid anything else?

2.Cannabis/hashish, benzodiazepams, alcohol, tobaco and narcotics are what I use sometimes on a daily basis so can any of those drugs do anything with the 5-HTP?

Also I should mention herbs since cat's claw I hear can potentate methadone significantly. I drink white, green, red tea and a few herbal teas as regularly as well (Mellissa, Chamomille, Linden flower, Horse Tail, Marigold, Mint, etc),

In those herbal teas is there anything I should look out for?

3. What physical effects does 5-HTP have on the body? Wikipedia says it creates jeart valve damage or disease. Even though it is natural and created in the body even, everything in excess has to do something bad! I firmly believe in that.

4. When should you take 5-HTP? Should one take it when feeling depressed?

5. In cases of seratonin depletion, I speculate that I have drained my brain out of a lot of seratonin this year and last with mdma and other seratoninergic drugs like methylone and mephedrone, how long should one take it? Would it be better to not take it at all? Does it improve memory?

What if you have used so much mdma, methylone and mephedrone that you are feeling fried for months, or at least not as bright/witty as before? However depression doesn't really happen that often.

6. Does 5-HTP act as an SSRI or a MAOi?

7. When balacing out the good results and the bad results do you feel it is worth it?

I would like to hear any experiences from people who have used it before for however long and for whatever reason! Every input is welcome!
 
It'll take a week of daily intake to truly produce the desired effects. In combination with Omega 3 i find it among the best anti depressants. SSRI class anti depressants have been reported by long term users to permanently change the brain. The fact is doctors get free lunches, gift certificates etc. to prescribes certain medications at your expense. Be very weary of anything a doctor is trying to prescribe for an unnecessary reason or condition you do not have.
 
ive been taking it for a couple of months now,they made feel great at first and now im taking less(50 mgs a night compared to 100 mgs a night)i go through some sort of withdraw.i fell worst than before i started taking 5-htp.im going to ween my self off and hope for the best...

i wish i could post more of my experiance with 5-htp but im tired,ill write more tommorow
 
i found some that come in 50mg pills
and normally take about two in the morning or two at night..
in the beginning it would give me some vivid fun dreams, would make weed feel stronger, and would make me happier and be in a good mood..
after a few days, some side effects came on that seemed to come on at random.. sometimes i would get stomach pain or headaches or sometimes both..
never took more than 200mg in a day..
and i take it before and after taking some methylone..
 
Alcohol in significant quantities is dangerous to combine with 5-HTP. Don't take 5-HTP if you plan to get boozed up, as it can cause seizures.
 
FrostyMcFailure said:
It'll take a week of daily intake to truly produce the desired effects.
Click to expand...

Not for me. I start to feel the effects the night and day after I start taking it: better sleep, less need for sleep, improved mood, lower appetite (that's unwanted for me), greater tolerance for stress, improved cognitive function.

5HTP rocks!
 
muie said:
1. Are there any precautions that need to be taken when you start 5-HTP? Besides seratoninergic drugs should you avoid anything else?
Click to expand...

As you hinted at, do not overlap 5-HTP with SSRIs or SSNIs. Or MOAIs, for that matter. Meaning, do not use it ontop of the popular anti-depressants or certain sleep-aids and OCD meds. For example, I had to cease my 5-HTP intake when I began taking Fluvoxamine to treat my OCD (an SSRI).

5-HTP works best when taken in junction with a daily vitamin, and/or a B-vitamin complex. So keep that in mind.

2.Cannabis/hashish, benzodiazepams, alcohol, tobaco and narcotics are what I use sometimes on a daily basis so can any of those drugs do anything with the 5-HTP?

Also I should mention herbs since cat's claw I hear can potentate methadone significantly. I drink white, green, red tea and a few herbal teas as regularly as well (Mellissa, Chamomille, Linden flower, Horse Tail, Marigold, Mint, etc),

In those herbal teas is there anything I should look out for?
Click to expand...

Herbs are fine. "Narcotics" is kind of a vague term when used socially. Can you expand on this? It shouldn't be a problem with popular opiates, though. Basically, think about what you would NOT want to mix with MDMA and don't mix such with 5-HTP.

3. What physical effects does 5-HTP have on the body? Wikipedia says it creates jeart valve damage or disease. Even though it is natural and created in the body even, everything in excess has to do something bad! I firmly believe in that.
Click to expand...

5-HTP is pretty subtle. If anything, it will help you feel calm and complacent (like a weak-benzo effect). Sure, I mean there's a minority of people who might get extreme side effects from it, and given that it's new it's not FDA-approved and has not been the subject of much research. But again, it's gentle compared to prescription anti-depressants.

4. When should you take 5-HTP? Should one take it when feeling depressed?
Click to expand...

It's either to be taken daily (bottles suggest before bed since it can have acute hypnotic effects for some) and/or part of a pre/post-loading regime to minimise the negative effects of drugs like MDxx. In the latter case, it's okay to take higher does, but daily use should stick between 50-100mg.

5. In cases of seratonin depletion, I speculate that I have drained my brain out of a lot of seratonin this year and last with mdma and other seratoninergic drugs like methylone and mephedrone, how long should one take it? Would it be better to not take it at all? Does it improve memory?

What if you have used so much mdma, methylone and mephedrone that you are feeling fried for months, or at least not as bright/witty as before? However depression doesn't really happen that often.
Click to expand...

You can take 5-HTP indefinately at a daily dose. Do NOT try and overload at the start in order to speed up the effects. Just like an anti-depressant, it takes several weeks to notice a change in mood. I know this sounds antangizing to what I said about its use in junction with MDMA before, but it you plan to use it to help your life (as opposed to short-term damage control), this is how you do it.

I have not read anything about it improving memory. With binging and semi-long-term effects like you describe, really time is your best friend. Not that you won't have any permanent effects if you went nuts with the seratonin drugs, but your body/brain will heal itself in time, with or without 5-HTP.


6. Does 5-HTP act as an SSRI or a MAOi?

No and no.

7. When balacing out the good results and the bad results do you feel it is worth it?

I would like to hear any experiences from people who have used it before for however long and for whatever reason! Every input is welcome!
Click to expand...

For me, it helped with pre/post-loading in juction with MDMA (though I don't know if this was power-of-suggestion or not). I did not notice anything from taking it for 3 months a la an anti-depressant. However, I know people who love it and say it's better than prescription anti-depressants. Everybody's different, but it's not really that dangerous and therefore something I suggest you try and see for yourself!

Best of fortune :)
 
5htp.

• Made me feel sleepy and weird all day
• Made my eyes bulge out or feel like they did
• Made drugs feel worse
• No appreciable effect on the after period of drugs
 
I took a capsule earlier an hour or so after taking a small dose of gbl and now feel rather sick :( Is there anyone else that has done 5-HTP at the same time as gbl and had a similar experience?
 
An Iz said:
nope, but it made me feel sick all on its own.
Click to expand...

yup.

the specific scientific explanation is somewhere else on BL, but the basic idea is that 5-HTP supplements lead to seratonin (which makes you nauseous) in the stomach, rather than just the brain.
 
I used to preload with 5HTP when I was rolling often ( maybe once a week )

I was also using it for quite some time after I slowed my harder drug use to help me sleep and uplift my mood.

I didn't notice a change in my mood until I was about a week in.

I prefer it to Paxil, which I have also taken in the past to combat a situational depression. I didn't like the side effects of Paxil. For me these effects included physical lethargy, and a slowing of my mental state. My head always felt heavy and in a fog. Mind you I was on it for a little over a month.

I stopped taking it, because I didn't like the idea of having to use it to feel right.

I still cycle through bouts of mild depression, but I just trugde through them knowing that I will have an upswing soon after.

I recommend taking 5HTP in the 50 to 100mg range 5 or six times a week.




...
 
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When I was buying 5htp the guy at the pharmacy told me that I should take one when I'm feeling really depressed and I should feel it in 30mins to an hour and if not then take another. I usually forget to check how I feel after that time so I'm guessing it works? lol.

Also, I pop one or two after a night of mdma and 1-3 in the following days, it helps avoid the mid-week crash.

Also, vitamin B3 helps with absorption.
 
You don't really feel 5htp ..

Well you do but it's after a few days of taking It and it's a very subtle effect .

Your obviously not going to feel it in the same day you first take it cause your body has to metabolize and convert the 5htp into serotonin and more
 
Alcohol in significant quantities is dangerous to combine with 5-HTP. Don't take 5-HTP if you plan to get boozed up, as it can cause seizures.
Click to expand...

How?


the specific scientific explanation is somewhere else on BL, but the basic idea is that 5-HTP supplements lead to seratonin (which makes you nauseous) in the stomach, rather than just the brain.
Click to expand...

80 percent of your 5ht receptors reside in the gut, and 5htp readily metabolizes to 5ht outside of the brain.

Also, vitamin B3 helps with absorption.
Click to expand...

I thought it was b6. Regardless, it's an open question: while b-vitamins aid metabolism into 5ht, this might lead a greater proportion of 5htp to convert into 5ht outside of the brain, and 5ht cannot cross the BBB.

ebola
 
when I smoked weed after taking 5-HTP I get super super high... beware

also, like other people said, don't combine 5-HTP and alcohol, as it can be deadly.
 
^ really ? . Smoking weed and taking 5-htp shows no unusual effects .


Why would it ?

Lol think about how the two work in totally different ways in the brain and body
 
5HTP + Alcohol

I've been taking 100mg before bed every night for the last month. Last weekend I went out and was drinking. I got pretty drunk, a lot faster than I normally do. I mean really really drunk. I almost ended up blacking out. I have a very high natural alcohol tolerance; I can usually drink 3 double Jameseons (neat of course) without feeling the slightest buzz at all. This time after just 2 vodka rocks' I was fucked up (and kept drinking, stupid as I am)

Anyway if you're on 5HTP be careful with alcohol
 
jamesmartin said:
^ really ? . Smoking weed and taking 5-htp shows no unusual effects .


Why would it ?

Lol think about how the two work in totally different ways in the brain and body
Click to expand...

I'm not a scientist, I just know that it makes my weed sessions turn into 5 or 6 hour trip sessions...
 
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