Tchort
Bluelight Crew
- Joined
- Mar 25, 2008
- Messages
- 2,392
I've been wondering lately about the worst ingredients in pills (tablets, dispersibles, capsule powder, etc) and solutions and whether there are particular binders, fillers and inactive ingredients that are too small to be caught in a micron filter ('wheel filter') or are soluble themselves and thus make it through to the final solution. Many ingredients in pills are fairly benign (Lactose, confectioners sugar), but some are simply made to do damage to IDU (Injecting Drug Users).
What do you need to know about a particular chemical to know if it will carry over to the end solution if pushed through a micron filter?
A rundown from wiki:
http://en.wikipedia.org/wiki/Wheel_filter
In particular, the products I am most worried about are:
[-1-] OxyContin
[-2-] Temazepam
[-3-] Cyclizine
[-4-] MS-Contin
[-5] Methadose
[-6-] Ritalin
[-7-] Suboxone
[-8-] Subutex
[-9-] Roxanol Concentrated Oral Solution
[-10-] Methadose Concentrated Oral Solution
The inactive ingredients present in all of these products:
(1) OxyContin
ammonio methacrylate copolymer, hypromellose, lactose, magnesium stearate, polyethylene glycol 400, povidone, sodium hydroxide, sorbic acid, stearyl alcohol, talc, titanium dioxide, and triacetin.
The 10 mg tablets also contain: hydroxypropyl cellulose.
The 20 mg tablets also contain: polysorbate 80 and red iron oxide.
The 40 mg tablets also contain: polysorbate 80 and yellow iron oxide.
The 80 mg tablets also contain: FD&C blue No. 2, hydroxypropyl cellulose, and yellow iron oxide.
The 160 mg tablets also contain: FD&C blue No. 2 and polysorbate 80.
http://www.drugs.com/pro/oxycontin.html
(2) Temazepam
7.5 mg Capsules
Inactive Ingredients: FD&C Blue #1, FD&C Red #3, gelatin, lactose, magnesium stearate, red iron oxide, titanium dioxide.
May also include: n-butyl alcohol, iron oxide red, shellac, shellac glaze, SD-35A alcohol.
15 mg Capsules
Inactive Ingredients: FD&C Blue #1, FD&C Red #3, gelatin, lactose, magnesium stearate, red iron oxide, titanium dioxide.
May also include: n-butyl alcohol, FD&C Blue #1 / Brilliant Blue FCF Aluminum Lake, iron oxide red, isopropyl alcohol, propylene glycol, shellac, shellac glaze, SD-35A alcohol, SD-45 alcohol.
22.5 mg Capsules
Inactive Ingredients: FD&C Blue #1, FD&C Red #3, gelatin, lactose, magnesium stearate, red iron oxide, titanium dioxide.
May also include: n-butyl alcohol, FD&C Blue #1 / Brilliant Blue FCF Aluminum Lake, iron oxide red, isopropyl alcohol, propylene glycol, shellac, shellac glaze, SD-35A alcohol, SD-45 alcohol.
30 mg Capsules
Inactive Ingredients: FD&C Blue #1, FD&C Red #3, gelatin, lactose, magnesium stearate, red iron oxide, titanium dioxide.
May also include: n-butyl alcohol, FD&C Blue #1 / Brilliant Blue FCF Aluminum Lake, iron oxide red, isopropyl alcohol, propylene glycol, shellac, shellac glaze, SD-35A alcohol, SD-45 alcohol.
http://www.drugs.com/pro/restoril.html
(3) Cyclizine
Inactive Ingredients: Anhydrous Lactose, Hydrogenated Vegetable Oil, Magnesium Stearate, Cellulose (Powdered), Pregelatinized Starch, Silicon Dioxide
http://www.planetrx.com/shop/detail.cfm/sku/ad124
(4) MS-Contin
MS Contin® Controlled-release Tablets 15 mg, 30 mg, 60 mg, 100 mg, and 200 mg contain the following inactive ingredients: cetostearyl alcohol, hydroxyethyl cellulose, hypromellose, magnesium stearate, polyethylene glycol, talc and titanium dioxide.
MS Contin® Controlled-release Tablets 15 mg also contains FD&C Blue No. 2, lactose and polysorbate 80.
MS Contin® Controlled-release Tablets 30 mg also contains D&C Red No. 7, FD&C Blue No. 1, lactose and polysorbate 80.
MS Contin® Controlled-release Tablets 60 mg also contains D&C Red No. 30, D&C Yellow No. 10, hydroxypropyl cellulose, and lactose.
MS Contin® Controlled-release Tablets 100 mg also contains black iron oxide.
MS Contin® Controlled-release Tablets 200 mg also contains D&C Yellow No. 10, FD&C Blue No. 1, and hydroxypropyl cellulose.
http://www.drugs.com/pro/ms-contin.html
(5) Methadose
Each tablet also contains Dibasic Calcium Phosphate USP, Microcrystalline Cellulose NF, Magnesium Stearate NF, Colloidal Silicon Dioxide NF, Pregelatinized Starch NF, and Stearic Acid NF.
http://www.drugs.com/pro/methadose.html
(6) Ritalin
Inactive Ingredients. Ritalin tablets: D&C Yellow No. 10 (5-mg and 20-mg tablets), FD&C Green No. 3 (10-mg tablets), lactose, magnesium stearate, polyethylene glycol, starch (5-mg and 10-mg tablets), sucrose, talc, and tragacanth (20-mg tablets).
Ritalin-SR tablets: Cellulose compounds, cetostearyl alcohol, lactose, magnesium stearate, mineral oil, povidone, titanium dioxide, and zein.
http://www.drugs.com/pro/ritalin.html
(7) Suboxone
Each tablet also contains lactose, mannitol, cornstarch, povidone K30, citric acid, sodium citrate, FD&C Yellow No.6 color, magnesium stearate, and the tablets also contain Acesulfame K sweetener and a lemon / lime flavor.
http://www.drugs.com/pro/suboxone.html
(8) Subutex
Each tablet also contains lactose, mannitol, cornstarch, povidone K30, citric acid, sodium citrate and magnesium stearate.
http://www.drugs.com/pro/suboxone.html
(9) Roxanol Concentrated Oral Solution
Inactive ingredients: ascorbic acid, citric acid, FD&C Blue
No. 1, FD&C Red No. 40, flavors, glycyrrhizin, propylene
glycol, purified water, saccharin sodium, sodium benzoate,
sodium gluconate, sodium phosphate dibasic, and sorbitol
solution.
http://www.ethex.com/pages/pdf/58177088601_PIS.pdf
(10) Methadose Concentrated Oral Solution
Other ingredients of Methadose Oral Concentrate: Artificial cherry flavor, citric acid anhydrous USP, FD&C Red No 40, D&C Red No 33, methylparaben NF, polaxamer 407 NF, propylene glycol USP, propylparaben NF, purified water USP, sodium citrate dihydrate USP, sucrose NF.
http://www.drugs.com/pro/methadose-conc.html
When looking over commonly injected pharmaceutical products that were not meant to be injected, several ingredients overlap. Unfortunately, it seems that several of these ingredients are more harmful than the others. Specifically, the following inactive ingredients I am most concerned about passing through a micron filter:
-Silicone Dioxide
-Titanium Dioxide
-Magnesium Stearate
-Povidone
-Hydroxypropyl Cellulose
-Sorbitol
-Propylene Glycol
-Microcrystalline Cellulose
Can anyone give me some assurance that a micron filter will filter out most if not all harmful inactives (specifically those listed above) from products being prepped for injection?
We commonly recommend people buy and use micron filters, and say that they take out everything except the active chemicals (street drugs, pills, syrups, everything). I find this hard to believe without more information.
What do you need to know about a particular chemical to know if it will carry over to the end solution if pushed through a micron filter?
A rundown from wiki:
In scientific applications, the most common sizes available are 0.2 or 0.22 µm and 0.44 µm pores. These sizes are sufficient for HPLC use. Membrane diameters of 10 mm, 13 mm, 25 mm are common as well. Some syringe filters for small volumes may be not resemble a wheel at all.
. . .
Syringe filters may be used to filter injectable illegal drugs such as heroin, methadone (Physeptone)*, amphetamines, ecstasy or benzodiazepines. The filter still lets the drug through, but gets rid of many impurities such as fungal spores, bacteria or 'filler' used in the drug. The use of wheel filters is strongly recommended when illicit drug users seek to inject prescription medications such as morphine and benzodiazepines that come in tablet form.
Pills like prescription opiates or benzodiazepines which are often converted by users into crude injectables, have ingredients such as chalk and wax as a 'filler', and illicit drugs are often adulterated with fillers to increase profits. Correctly used, wheel filters greatly reduce these impurities entering the blood stream and will help avoid vein problems such as collapsed veins, abscesses, infections, embolism, 'dirty tastes', disease and septicemia.
While wheel filters are the most effective filter available for injecting drug users along with luer lock syringe tip filters, other more common types of filters used include cotton wool, tampons, and cigarette filters. While these can serve as basic filters, they have a greater risk of bacterial infection or contamination from pieces of the filter itself. The condition known as cotton fever is caused by bacteria present in cotton used as a filter.
http://en.wikipedia.org/wiki/Wheel_filter
In particular, the products I am most worried about are:
[-1-] OxyContin
[-2-] Temazepam
[-3-] Cyclizine
[-4-] MS-Contin
[-5] Methadose
[-6-] Ritalin
[-7-] Suboxone
[-8-] Subutex
[-9-] Roxanol Concentrated Oral Solution
[-10-] Methadose Concentrated Oral Solution
The inactive ingredients present in all of these products:
(1) OxyContin
ammonio methacrylate copolymer, hypromellose, lactose, magnesium stearate, polyethylene glycol 400, povidone, sodium hydroxide, sorbic acid, stearyl alcohol, talc, titanium dioxide, and triacetin.
The 10 mg tablets also contain: hydroxypropyl cellulose.
The 20 mg tablets also contain: polysorbate 80 and red iron oxide.
The 40 mg tablets also contain: polysorbate 80 and yellow iron oxide.
The 80 mg tablets also contain: FD&C blue No. 2, hydroxypropyl cellulose, and yellow iron oxide.
The 160 mg tablets also contain: FD&C blue No. 2 and polysorbate 80.
http://www.drugs.com/pro/oxycontin.html
(2) Temazepam
7.5 mg Capsules
Inactive Ingredients: FD&C Blue #1, FD&C Red #3, gelatin, lactose, magnesium stearate, red iron oxide, titanium dioxide.
May also include: n-butyl alcohol, iron oxide red, shellac, shellac glaze, SD-35A alcohol.
15 mg Capsules
Inactive Ingredients: FD&C Blue #1, FD&C Red #3, gelatin, lactose, magnesium stearate, red iron oxide, titanium dioxide.
May also include: n-butyl alcohol, FD&C Blue #1 / Brilliant Blue FCF Aluminum Lake, iron oxide red, isopropyl alcohol, propylene glycol, shellac, shellac glaze, SD-35A alcohol, SD-45 alcohol.
22.5 mg Capsules
Inactive Ingredients: FD&C Blue #1, FD&C Red #3, gelatin, lactose, magnesium stearate, red iron oxide, titanium dioxide.
May also include: n-butyl alcohol, FD&C Blue #1 / Brilliant Blue FCF Aluminum Lake, iron oxide red, isopropyl alcohol, propylene glycol, shellac, shellac glaze, SD-35A alcohol, SD-45 alcohol.
30 mg Capsules
Inactive Ingredients: FD&C Blue #1, FD&C Red #3, gelatin, lactose, magnesium stearate, red iron oxide, titanium dioxide.
May also include: n-butyl alcohol, FD&C Blue #1 / Brilliant Blue FCF Aluminum Lake, iron oxide red, isopropyl alcohol, propylene glycol, shellac, shellac glaze, SD-35A alcohol, SD-45 alcohol.
http://www.drugs.com/pro/restoril.html
(3) Cyclizine
Inactive Ingredients: Anhydrous Lactose, Hydrogenated Vegetable Oil, Magnesium Stearate, Cellulose (Powdered), Pregelatinized Starch, Silicon Dioxide
http://www.planetrx.com/shop/detail.cfm/sku/ad124
(4) MS-Contin
MS Contin® Controlled-release Tablets 15 mg, 30 mg, 60 mg, 100 mg, and 200 mg contain the following inactive ingredients: cetostearyl alcohol, hydroxyethyl cellulose, hypromellose, magnesium stearate, polyethylene glycol, talc and titanium dioxide.
MS Contin® Controlled-release Tablets 15 mg also contains FD&C Blue No. 2, lactose and polysorbate 80.
MS Contin® Controlled-release Tablets 30 mg also contains D&C Red No. 7, FD&C Blue No. 1, lactose and polysorbate 80.
MS Contin® Controlled-release Tablets 60 mg also contains D&C Red No. 30, D&C Yellow No. 10, hydroxypropyl cellulose, and lactose.
MS Contin® Controlled-release Tablets 100 mg also contains black iron oxide.
MS Contin® Controlled-release Tablets 200 mg also contains D&C Yellow No. 10, FD&C Blue No. 1, and hydroxypropyl cellulose.
http://www.drugs.com/pro/ms-contin.html
(5) Methadose
Each tablet also contains Dibasic Calcium Phosphate USP, Microcrystalline Cellulose NF, Magnesium Stearate NF, Colloidal Silicon Dioxide NF, Pregelatinized Starch NF, and Stearic Acid NF.
http://www.drugs.com/pro/methadose.html
(6) Ritalin
Inactive Ingredients. Ritalin tablets: D&C Yellow No. 10 (5-mg and 20-mg tablets), FD&C Green No. 3 (10-mg tablets), lactose, magnesium stearate, polyethylene glycol, starch (5-mg and 10-mg tablets), sucrose, talc, and tragacanth (20-mg tablets).
Ritalin-SR tablets: Cellulose compounds, cetostearyl alcohol, lactose, magnesium stearate, mineral oil, povidone, titanium dioxide, and zein.
http://www.drugs.com/pro/ritalin.html
(7) Suboxone
Each tablet also contains lactose, mannitol, cornstarch, povidone K30, citric acid, sodium citrate, FD&C Yellow No.6 color, magnesium stearate, and the tablets also contain Acesulfame K sweetener and a lemon / lime flavor.
http://www.drugs.com/pro/suboxone.html
(8) Subutex
Each tablet also contains lactose, mannitol, cornstarch, povidone K30, citric acid, sodium citrate and magnesium stearate.
http://www.drugs.com/pro/suboxone.html
(9) Roxanol Concentrated Oral Solution
Inactive ingredients: ascorbic acid, citric acid, FD&C Blue
No. 1, FD&C Red No. 40, flavors, glycyrrhizin, propylene
glycol, purified water, saccharin sodium, sodium benzoate,
sodium gluconate, sodium phosphate dibasic, and sorbitol
solution.
http://www.ethex.com/pages/pdf/58177088601_PIS.pdf
(10) Methadose Concentrated Oral Solution
Other ingredients of Methadose Oral Concentrate: Artificial cherry flavor, citric acid anhydrous USP, FD&C Red No 40, D&C Red No 33, methylparaben NF, polaxamer 407 NF, propylene glycol USP, propylparaben NF, purified water USP, sodium citrate dihydrate USP, sucrose NF.
http://www.drugs.com/pro/methadose-conc.html
When looking over commonly injected pharmaceutical products that were not meant to be injected, several ingredients overlap. Unfortunately, it seems that several of these ingredients are more harmful than the others. Specifically, the following inactive ingredients I am most concerned about passing through a micron filter:
-Silicone Dioxide
-Titanium Dioxide
-Magnesium Stearate
-Povidone
-Hydroxypropyl Cellulose
-Sorbitol
-Propylene Glycol
-Microcrystalline Cellulose
Can anyone give me some assurance that a micron filter will filter out most if not all harmful inactives (specifically those listed above) from products being prepped for injection?
We commonly recommend people buy and use micron filters, and say that they take out everything except the active chemicals (street drugs, pills, syrups, everything). I find this hard to believe without more information.