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get high on vivitrol?

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Naltrexone doesn't antagonise learning. Learning is rooted in the dopamine/cholinergic pathways of the hippocampus. I was naltrexone for 4 months and I learned just fine. As for the natural highs from exercise, you're right, that was antagonised by naltrexone
 
Thats not true.

Its suppossed to be around 12mg bupe that TOTALLY blocks heroin.

If your on lower doses then you will start to feel H more and more.

Your on the same dose as me right? (around 1.5mg) - if you were to shoot a bag of brown it would blow your fucking head off.

Doses at 2mg or less seem to have absolutely no blocking effect at all.

I take around 0.3mg of buprenorphine at a time, so yeah, I'm sure IVing a bag of heroin would blow my head off.

However, the lingering buprenorphine in ones system competes for the receptor too, so you have to "shoot past" the buprenorphine.

And if you're taking heroin and then take buprenorphine, you'll go into precipitated WD's, if you're taking mu-agonists, you can take methadone while still feeling the effects.

He is obviously very careful with it and he is fine, I am willing to bet that he will never get in situation that resembles anything comparable to what we read in case studies.
This is true.

other then utilizing higest amount there is no benefit to inject bupe when you are on maintenance doses.
I definitely think there's a better effect when done this way, typically only when your opiate tolerance has lowered significantly. With a high opiate tolerance, it's pointless to inject it as you said, I agree. When one has a low opiate tolerance, the feeling is really pleasant and relaxing.
 
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That's not what I meant. Learning produces a mild opioid 'high' which is likely a part of the reason why we find learning rewarding.
 
I take around 0.3mg of buprenorphine at a time, so yeah, I'm sure IVing a bag of heroin would blow my head off.

However, the lingering buprenorphine in ones system competes for the receptor too, so you have to "shoot past" the buprenorphine.

And if you're taking heroin and then take buprenorphine, you'll go into precipitated WD's, if you're taking mu-agonists, you can take methadone while still feeling the effects.

.

When I go on heroin binges - I still take my subutex every day, about 1mg. It doesn't put me into WD, nor does it effect the high. It just makes it *much* easier to go back to just bupe when the smack runs out.
 
That's not what I meant. Learning produces a mild opioid 'high' which is likely a part of the reason why we find learning rewarding.

I see your point, and I'm sure it's possible that endorphins are involved in learning to some degree, the reward system is defnitely dopaminergic. I see what you're saying though; naltrexone does fuck with your endogenous neurotransmitter and endocrine systems
 
I dont know if I would say the health care system here is fucked. I have health insurance, and im fine paying a 5$ copay for my medications. For the ones who aren't this lucky: We dont have a socialist government like canada and the AU.
word dude.
 
I dont know if I would say the health care system here is fucked. I have health insurance, and im fine paying a 5$ copay for my medications. For the ones who aren't this lucky: We dont have a socialist government like canada and the AU. We run with the "In the US, you can do whatever you want to do...".

It is fucked b/c healthcare shouldn't be something that only the rich can afford. Why should it be that only people with $300 cash can afford suboxone. There is absolutely nothing wrong with a socialist health system. I have private health insurance so can get whatever surgery/treatment I need whenever I need it, but if I couldn't afford it I surely wouldn't want a corporation like an HMO deciding when/if I can get surgery. If it was as simple as a $5 copay for everything like it is here then that'd be fine, but what about the people who need to pay huge sums of cash to get on bupe maintenance; how is that fair?
 
US healthcare seems really fucked up, I recently saw Sicko by Michael Moore and if half of whats in the movie is true, situation is more then HORRIBLE. Movie is REALLY worth watching.

I wouldn't know about the movie but my cat was playing with the keyboard and this page came up, cat pressed download link too and opened it in movie player, so accidentaly I saw the movie. Ofcourse, I reported my cat for downloading copyrighted material and deleted the torrent


This is exactly what I'm arguing though, it's these people - the ones who bounce from bupe to heroin and back - who need to be supervised the most. It's these patients who can't control their opiate use who need supervised dosing, because in those 1 or 2 months where a high can be obtained from bupe, you can bet your ass it will be obtained at the expense of daily dosing. I'm not for a second saying bupe maintenance shouldn't ever be takeaway, but I do think certain people trying to get clean from an opiate habit need at least a month or 2 of supervised dosing, be it from a pharmacist or a guardian. And b/c it's so hard to separate those who can successfully dose at home from those who can't, I think the Australian system is done very well.

I agree with you as long as there is choice. Why would someone who has available guardian (a parent, relative, trusty friend) be forced to have his life revolving around going to clinic every morning.

I am myself on bupe and I work and travel a lot. Being forced to go to clinic to get my dose would make me choose to stay on fent/h or whatever opiate I could get.

I simply don't have time to go to clinic every morning (not to mention that closest clinic is faaaaaar away, but lets pretend it's in my town for the sake of discussion) because I am very busy person. Bupe gave me my life back, but by having that life back I am now burried with responsibilities and having my well-being revolving around being at clinic EVERY day at RIGHT time would simply make that impossible.

On the other hand, I understand your point. Some people are just out of control,. At beginning of maintenance I chose to have a guardian who will take care of my supply - even though I wasn't forced to do that.
Right now my wifey is taking care of subs and dividing the pills, however I take multiple doses per day and stock of "packages" enough for 2-3 days is always accessible to me.

I mean I know where the rest of stash is, but I feel better when someone else is taking care of my dosage, (I am slowly tappering), I just take the dose without questioning how much is in it, and I take it as often as it's required to feel normal. I am on 4-5mg a day now, slowly decreasing average dose.
 
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It is fucked b/c healthcare shouldn't be something that only the rich can afford. Why should it be that only people with $300 cash can afford suboxone. There is absolutely nothing wrong with a socialist health system. I have private health insurance so can get whatever surgery/treatment I need whenever I need it, but if I couldn't afford it I surely wouldn't want a corporation like an HMO deciding when/if I can get surgery. If it was as simple as a $5 copay for everything like it is here then that'd be fine, but what about the people who need to pay huge sums of cash to get on bupe maintenance; how is that fair?

I agree that there needs to be improvements, but what about the advancement in healthcare and pharms in the US?

We're attempting to do something about it now, but generally a non-socialist country isn't "big brother" with everything.

US healthcare seems really fucked up, I recently saw Sicko by Michael Moore and if half of whats in the movie is true, situation is more then HORRIBLE. Movie is REALLY worth watching.

I wouldn't know about the movie but my cat was playing with the keyboard and this page came up, cat pressed download link too and opened it in movie player, so accidentaly I saw the movie. Ofcourse, I reported my cat for downloading copyrighted material and deleted the torrent




I agree with you as long as there is choice. Why would someone who has available guardian (a parent, relative, trusty friend) be forced to have his life revolving around going to clinic every morning.

I am myself on bupe and I work and travel a lot. Being forced to go to clinic to get my dose would make me choose to stay on fent/h or whatever opiate I could get.

I simply don't have time to go to clinic every morning (not to mention that closest clinic is faaaaaar away, but lets pretend it's in my town for the sake of discussion) because I am very busy person. Bupe gave me my life back, but by having that life back I am now burried with responsibilities and having my well-being revolving around being at clinic EVERY day at RIGHT time would simply make that impossible.

On the other hand, I understand your point. Some people are just out of control,. At beginning of maintenance I chose to have a guardian who will take care of my supply - even though I wasn't forced to do that.
Right now my wifey is taking care of subs and dividing the pills, however I take multiple doses per day and stock of "packages" enough for 2-3 days is always accessible to me.

I mean I know where the rest of stash is, but I feel better when someone else is taking care of my dosage, (I am slowly tappering), I just take the dose without questioning how much is in it, and I take it as often as it's required to feel normal. I am on 4-5mg a day now, slowly decreasing average dose.

Please don't look at Michael Moore's movies as fact. He raises good point, but generally a lot of what he has to say is one-sided.
 
The fact that drug addicts don't get FREE substitute perscribing is shocking imo.

Its hardly suprising that those often in the most dire need of help have no insurance and no money.

The US is the richest country on earth, yet it apparantly can't afford to look after it own people.

Anyway, who the FUCK would want an insurance company to have their life in their hands. Its bad enough having to insure my car through the cunts. Fuck that.

Their primary concern is making money - not paying out and looking after people.

Completely fucked.
 
So is the UK.

In fact, so the rest of EUROPE.

Doesn't stop us getting free health care and prescriptions.
 
I find this pathetically cruel. They're lowering your "base" of well being by fucking with your endogenous opioid system.

I guess it isn't as bad as in China where they're surgically removing the pleasure centers. :(

This.

That is why I was so horrified upon reading the initial post. Disabling a person's ability to feel any "normal" pleasure sounds not only cruel, but counterproductive to me. I did a cold turkey when I finally got clean, and I could actually feel it when my endogenous opiates began to fire up and take hold again. Opiate withdrawals are bad enough, but not to be able to anticipate any relief even after the (3/5/7/10 however many days)? That sounds like the stuff nightmares are made of!

Obviously, I am neither the OP's parent nor her doctor, so I don't know her history, but a controlled, supervised administration of bupe seems to me like it would have been not only more humane, but also maybe more likely to help her maintain her sobriety, going forward.
 
God Damn i feel you man ive been on the shot for 10 days forced by my parents(senior at pennstate need the help) now im just sitting here typing staring at 10 opana 40s ers wanting to shoot myself i really want to get high but oxymorphone is so precious i dont wna waste it its not just your average street dope....any advice?
 
God Damn i feel you man ive been on the shot for 10 days forced by my parents(senior at pennstate need the help) now im just sitting here typing staring at 10 opana 40s ers wanting to shoot myself i really want to get high but oxymorphone is so precious i dont wna waste it its not just your average street dope....any advice?

You're just going to have to ride it out, they aren't going to do anything for you right now. The best advice is to use this time to your advantage and get off of opioids, but thats your call.

I'm going to go ahead and close this thread because its really old and frankly probably would not be allowed to stay open under the current rules.
 
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