If it's dirty dope, or generally any type of anhydrous dope that you're smoking, it can make you sick. Trust me, nothing makes me gag worse than taking a hit of some fire anhydrous that hasn't been prepared by a pro...bleccch!! Just thinking about it makes me nauseous. So yeah, smoked methamphetamine can make you feel that way...not just because of the smell, taste, poor quality or whatever, but as mentioned above nausea is a common side effect with methamp / amps.